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Find clinical trials for Heart Disease in Birmingham, AL

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Aortic Valve Stenosis

Heart Disease trials near Birmingham, AL, USA:

Harmony TPV Post-Approval Study

The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...

Enrolling
Congenital Heart Disease
Tetrology of Fallot
Device: Harmony TPV System
Covidien
Covidien

Birmingham, Alabama, United States and 20 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

Birmingham, Alabama, United States and 82 other locations

open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Birmingham, Alabama, United States and 74 other locations

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

Birmingham, Alabama, United States and 103 other locations

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling
Cardiovascular Diseases
Heart Failure Preserved Ejection Fraction
Drug: Placebo
Drug: Tovinontrine (CRD-750

Phase 2

Cardurion Pharmaceuticals

Birmingham, Alabama, United States and 58 other locations

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling
Cardiovascular Diseases
Heart Failure With Reduced Ejection Fraction
Drug: Tovinontrine (CRD-750)
Drug: Placebo

Phase 2

Cardurion Pharmaceuticals

Birmingham, Alabama, United States and 70 other locations

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

Birmingham, Alabama, United States and 84 other locations

To establish the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve (THV) in patients with severe, calcific aortic s...

Active, not recruiting
Aortic Stenosis
Procedure: SAVR
Device: SAPIEN 3 THV
Edwards Lifesciences
Edwards Lifesciences

Birmingham, Alabama, United States and 76 other locations

2nd generation DES for the treatment of subjects with ischemic heart disease (NSTEMI, recent STEMI (\>24 hours from initial present...

Active, not recruiting
Coronary Artery Disease
Device: 2nd generation DES (XIENCE family, Promus family, Resolute/Onyx family/Endeavor, and Orsiro stent)
Device: Microport Firehawk stent
MicroPort

Birmingham, Alabama, United States and 56 other locations

The purpose of this study is to establish the safety and effectiveness of pulsed field ablation as a first-line ablation treatment for subjects with...

Enrolling
Persistent Atrial Fibrillation
Device: FARAPULSE™ Pulsed Field Ablation (PFA) System
Drug: Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Boston Scientific
Boston Scientific

Birmingham, Alabama, United States and 66 other locations

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