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is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...
Phase 2
Rock Hill, South Carolina, United States and 64 other locations
The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Dr...
Charlotte, North Carolina, United States and 10 other locations
The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...
Charlotte, North Carolina, United States and 20 other locations
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failin...
Charlotte, North Carolina, United States and 50 other locations
To establish the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve (THV) in patients with severe, calcific aortic s...
Charlotte, North Carolina, United States and 76 other locations
This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with c...
Charlotte, North Carolina, United States and 76 other locations
2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...
Charlotte, North Carolina, United States and 131 other locations
This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults wi...
Phase 3
Charlotte, North Carolina, United States and 851 other locations
This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...
Phase 3
Statesville, North Carolina, United States and 584 other locations
The primary objective of this study is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease...
Phase 3
Charlotte, North Carolina, United States and 736 other locations
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