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Find clinical trials for Heart Disease in Montréal, QC

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Myocardial Ischemia
Heart Failure
Coronary Disease
Hypertension

Heart Disease trials near Montréal, QC, CAN:

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

of MAS825, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 28 people with known coronary heart...

Enrolling
Coronary Heart Disease
Clonal Hematopoiesis of Indeterminate Potential (CHIP)
Drug: DFV890 placebo
Drug: DFV890

Phase 2

Novartis
Novartis

Montreal, Quebec, Canada and 1 other location

is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...

Enrolling
Heart Failure
Pulmonary Hypertension (World Health Organization Group 2)
Drug: AZD3427
Drug: Placebo

Phase 2

AstraZeneca
AstraZeneca

Montreal, Quebec, Canada and 63 other locations

A multicenter, randomized clinical trial to assess whether catheter ablation or antiarrhythmic drug therapy provides the most effective control of im...

Active, not recruiting
Ventricular Tachycardia (VT)
Procedure: Catheter ablation
Drug: Antiarrythmic Drug Therapy

Phase 4

John Sapp

Montreal, Quebec, Canada and 20 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

Montréal, Canada and 71 other locations

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Montreal, Quebec, Canada and 467 other locations

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

Montreal, Quebec, Canada and 84 other locations

reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart F...

Active, not recruiting
Heart Failure
Other: Placebo
Drug: Finerenone (BAY94-8862)

Phase 3

Bayer
Bayer

Montreal, Quebec, Canada and 663 other locations

This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...

Enrolling
Cardiovascular Disease
Drug: Semaglutide
Drug: Cagrilintide

Phase 3

Novo Nordisk
Novo Nordisk

Montreal, Quebec, Canada and 521 other locations

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults wi...

Active, not recruiting
Coronary Heart Disease (CHD)
Drug: Evolocumab
Drug: Placebo

Phase 3

Amgen
Amgen

Montreal, Quebec, Canada and 851 other locations

multicentre, unblinded, randomised-controlled trial. The primary aim is to assess a targeted screening strategy to detect undiagnosed heart ...

Enrolling
Cardiovascular Diseases
Heart Failure
Diagnostic Test: NT-proBNP
NHS Trust
NHS Trust

Montréal, Quebec, Canada and 6 other locations

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