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This is a randomized, double-blind (DB), placebo controlled, crossover study with a two-period, two-sequence (2x2) design evaluating the efficacy and...
Phase 2
Louisville, Kentucky, United States and 43 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Louisville, Kentucky, United States and 195 other locations
This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized, double blind, placebo controlled study. Part 1 (phase 2b) is a do...
Phase 2, Phase 3
Louisville, Kentucky, United States and 160 other locations
of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...
Phase 3
Louisville, Kentucky, United States and 744 other locations
(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...
Phase 3
Louisville, Kentucky, United States and 950 other locations
The ALIGN Study is a phase 3, double-blind, placebo-controlled study to compare the efficacy and safety of atrasentan to placebo in patients with IgA...
Phase 3
Louisville, Kentucky, United States and 135 other locations
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatmen...
Phase 3
Louisville, Kentucky, United States and 21 other locations
The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabete...
Phase 3
Louisville, Kentucky, United States and 395 other locations
The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and...
Phase 2
Louisville, Kentucky, United States and 104 other locations
To determine the long-term (approximately 2 years) nephroprotective potential of treatment with sparsentan as compared to an angiotensin receptor blo...
Phase 3
Louisville, Kentucky, United States and 161 other locations
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