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This is a randomized, double-blind (DB), placebo controlled, crossover study with a two-period, two-sequence (2x2) design evaluating the efficacy and...
Phase 2
Louisville, Kentucky, United States and 43 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Louisville, Kentucky, United States and 206 other locations
with end stage kidney disease (ESKD) undergoing maintenance dialysis....
Phase 2, Phase 3
Louisville, Kentucky, United States and 197 other locations
of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...
Phase 3
Louisville, Kentucky, United States and 788 other locations
(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...
Phase 3
Louisville, Kentucky, United States and 950 other locations
The ALIGN Study is a phase 3, double-blind, placebo-controlled study to compare the efficacy and safety of atrasentan to placebo in patients with IgA...
Phase 3
Louisville, Kentucky, United States and 135 other locations
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatmen...
Phase 3
Louisville, Kentucky, United States and 21 other locations
(IG) for hemodialysis (HD) access in patients with end-stage renal disease (ESRD). The primary study endpoints are:Primary Effectiveness End...
Louisville, Kentucky, United States and 10 other locations
The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabete...
Phase 3
Louisville, Kentucky, United States and 392 other locations
The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and...
Phase 2
Louisville, Kentucky, United States and 63 other locations
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