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This is a randomized, double-blind (DB), placebo controlled, crossover study with a two-period, two-sequence (2x2) design evaluating the efficacy and...
Phase 2
Louisville, Kentucky, United States and 43 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Louisville, Kentucky, United States and 213 other locations
with end stage kidney disease (ESKD) undergoing maintenance dialysis....
Phase 2, Phase 3
Louisville, Kentucky, United States and 299 other locations
of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...
Phase 3
Louisville, Kentucky, United States and 845 other locations
The ALIGN Study is a phase 3, double-blind, placebo-controlled study to compare the efficacy and safety of atrasentan to placebo in patients with IgA...
Phase 3
Louisville, Kentucky, United States and 135 other locations
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatmen...
Phase 3
Louisville, Kentucky, United States and 21 other locations
(IG) for hemodialysis (HD) access in patients with end-stage renal disease (ESRD). The primary study endpoints are:Primary Effectiveness End...
Louisville, Kentucky, United States and 10 other locations
implicated in the inflammatory chemokine environment of chronic disease. The purpose of this pivotal randomized double-blind study is to inv...
Phase 3
Louisville, Kentucky, United States and 219 other locations
The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabete...
Phase 3
Louisville, Kentucky, United States and 370 other locations
The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and...
Phase 2
Louisville, Kentucky, United States and 63 other locations
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