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The overarching objective of this study is to use novel precision medicine strategies based on inherited and acquired leukemia-specific geno...
Phase 2, Phase 3
Charlotte, North Carolina, United States and 7 other locations
chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...
Phase 2
Charlotte, North Carolina, United States and 110 other locations
chemotherapy in induction-eligible patients with acute myeloid leukemia.This study involves the following:Venetoclax and azacitidine (invest...
Phase 2
Charlotte, North Carolina, United States and 8 other locations
The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of JNJ-75276617 in combination with AML directed therapies...
Phase 1
Charlotte, North Carolina, United States and 29 other locations
Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess retr...
Phase 2
Charlotte, North Carolina, United States and 47 other locations
A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic leukemia ...
Phase 3
Charlotte, North Carolina, United States and 40 other locations
(R/R) lymphomamultiple myelomanewly diagnosed acute myeloid leukemia (AML).This trial will be conducted in the outpatient setting in 2 parts...
Phase 1
Charlotte, North Carolina, United States and 61 other locations
previously treated or untreated with high risk factor acute myeloid leukemia (AML). Venetoclax and azacitidine are front-line therapy for su...
Phase 1
Charlotte, North Carolina, United States and 2 other locations
This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orall...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 44 other locations
in children with relapsed or refractory acute lymphoblastic leukemia (ALL).Determine the maximum tolerated dose (MTD) and to recommend a pha...
Phase 1
Charlotte, North Carolina, United States and 122 other locations
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