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Find clinical trials for Leukemia in Orlando, FL

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Related conditions:

Myeloid Leukemia
Acute Myeloid Leukemia
Lymphoid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myelodysplastic Syndromes

Leukemia trials near Orlando, FL, USA:

Feasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (ALL)

complete outpatient blinatumomab administration for subjects with minimal/measurable residual disease (MRD) of B-precursor Acute Lymphoblastic Leukemia...

Enrolling
B-precursor Acute Lymphoblastic Leukemia
Device: Current Wearable Heatlth Monitoring System (CWHMS)
Drug: Blinatumomab

Phase 4

Amgen
Amgen

Orlando, Florida, United States and 11 other locations

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting
Leukemia
Drug: Cytarabine
Drug: Leucovorin Calcium

Phase 2

Incyte
Incyte

Orlando, Florida, United States and 110 other locations

This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) or AML secondary to prior m...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Placebo
Drug: Oral Azacitidine

Phase 3

Celgene
Celgene

Orlando, Florida, United States and 222 other locations

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared wi...

Active, not recruiting
Leukemia, Myeloid, Acute
Leukemia, Myelomonocytic, Chronic
Drug: Pevonedistat
Drug: Azacitidine

Phase 3

Takeda
Takeda

Orlando, Florida, United States and 240 other locations

with azacitidine to improve Overall Survival (OS) in Acute Myeloid Leukemia (AML) participants compared to Best Supportive Care (BSC) when g...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Cancer
Other: Best Supportive Care (BSC)
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Orlando, Florida, United States and 164 other locations

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orall...

Active, not recruiting
Blastic Phase Chronic Myelogenous Leukemia
Chronic Phase Chronic Myelogenous Leukemia
Drug: Bosutinib

Phase 1, Phase 2

Children's Oncology Group

Orlando, Florida, United States and 44 other locations

The purpose of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL. Participants...

Enrolling
Leukemia, B-cell
Leukemia, Lymphocytic
Drug: Pirtobrutinib
Drug: Ibrutinib

Phase 3

Loxo Oncology
Loxo Oncology

Lakeland, Florida, United States and 179 other locations

The safety run-in part of the study aims to evaluate the safety and tolerability of blinatumomab alternating with low-intensity chemotherapy. The pha...

Enrolling
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Drug: Low-intensity chemotherapy regimen
Drug: Blinatumomab

Phase 3

Amgen
Amgen

Orlando, Florida, United States and 130 other locations

Locations recently updated

The purpose of this study is to evaluate the efficacy and safety of nemtabrutinib compared to investigator's choice of fludarabine plus cyclophospham...

Enrolling
Small Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
Drug: Bendamustine
Drug: Cyclophosphamide

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Clermont, Florida, United States and 90 other locations

The main aim is to see how the combination of pevonedistat + venetoclax + azacitidine compares to venetoclax + azacitidine in adults recently diagnos...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: Venetoclax
Drug: Pevonedistat

Phase 2

Takeda
Takeda

Orlando, Florida, United States and 56 other locations

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