Find clinical trials for Leukemia in Orlando, FL

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Related conditions:

Myeloid Leukemia

Acute Myeloid Leukemia

Lymphoid Leukemia

B-Cell Chronic Lymphocytic Leukemia

Lymphoma

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Myelodysplastic Syndromes

Leukemia trials near Orlando, FL, USA:

Locations recently updated

Feasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (ALL)

complete outpatient blinatumomab administration for subjects with minimal/measurable residual disease (MRD) of B-precursor Acute Lymphoblastic Leukemia...

Enrolling

B-precursor Acute Lymphoblastic Leukemia

Drug: Blinatumomab

Device: Current Wearable Heatlth Monitoring System (CWHMS)

Phase 4

Amgen

Orlando, Florida, United States and 11 other locations

A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting

Leukemia

Drug: Methotrexate

Drug: Thioguanine

Phase 2

Incyte

Orlando, Florida, United States and 110 other locations

Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission (QUAZAR AML-001)

This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) or AML secondary to prior m...

Active, not recruiting

Leukemia, Myeloid, Acute

Drug: Placebo

Drug: Oral Azacitidine

Phase 3

Celgene

Orlando, Florida, United States and 222 other locations

Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML) (PANTHER)

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared wi...

Active, not recruiting

Leukemia, Myeloid, Acute

Leukemia, Myelomonocytic, Chronic

Drug: Pevonedistat

Drug: Azacitidine

Phase 3

Takeda

Orlando, Florida, United States and 240 other locations

Locations recently updated

A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML) (VIALE-T)

with azacitidine to improve Overall Survival (OS) in Acute Myeloid Leukemia (AML) participants compared to Best Supportive Care (BSC) when g...

Active, not recruiting

Acute Myeloid Leukemia (AML)

Cancer

Drug: Venetoclax

Drug: Azacitidine

Phase 3

AbbVie

Orlando, Florida, United States and 164 other locations

Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orall...

Active, not recruiting

Blastic Phase Chronic Myelogenous Leukemia

Chronic Phase Chronic Myelogenous Leukemia

Drug: Bosutinib

Phase 1, Phase 2

Children's Oncology Group

Orlando, Florida, United States and 44 other locations

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) (BRUIN-CLL-314)

The purpose of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL. Participants...

Enrolling

Leukemia, B-cell

Leukemia, Lymphocytic

Drug: Pirtobrutinib

Drug: Ibrutinib

Phase 3

Loxo Oncology

Lakeland, Florida, United States and 179 other locations

A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)

Researchers are looking for new ways to treat people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). CLL and SL...

Enrolling

Small Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Drug: Bendamustine

Drug: Cyclophosphamide

Phase 3

Merck Sharp & Dohme (MSD)

Clermont, Florida, United States and 93 other locations

Locations recently updated

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

The safety run-in part of the study aims to evaluate the safety and tolerability of blinatumomab alternating with low-intensity chemotherapy. The pha...

Enrolling

Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)

Drug: Low-intensity chemotherapy regimen

Drug: Blinatumomab

Phase 3

Amgen

Orlando, Florida, United States and 144 other locations

A Study of Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy (PEVENAZA)

The main aim is to see how the combination of pevonedistat + venetoclax + azacitidine compares to venetoclax + azacitidine in adults recently diagnos...

Active, not recruiting

Acute Myeloid Leukemia (AML)

Drug: Venetoclax

Drug: Pevonedistat

Phase 2

Takeda

Orlando, Florida, United States and 56 other locations

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Find clinical trials for Leukemia in .css-epvm6{white-space:nowrap;}Orlando, FL

Related conditions:

Leukemia trials near Orlando, FL, USA:

Feasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (ALL)

A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission (QUAZAR AML-001)

Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML) (PANTHER)

A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML) (VIALE-T)

Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) (BRUIN-CLL-314)

A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

A Study of Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy (PEVENAZA)

Find clinical trials for Leukemia in Orlando, FL