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of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets CD19 which is located on the leukemia...
Phase 1, Phase 2
Orlando, Florida, United States and 24 other locations
chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...
Phase 2
Orlando, Florida, United States and 110 other locations
This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orall...
Phase 1, Phase 2
Orlando, Florida, United States and 58 other locations
chemotherapy in participants with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) negative acute myeloid leukemia...
Phase 3
Kissimmee, Florida, United States and 277 other locations
The safety run-in part of the study aims to evaluate the safety and tolerability of blinatumomab alternating with low-intensity chemotherapy. The pha...
Phase 3
Orlando, Florida, United States and 189 other locations
This study will be divided into 2 parts (Part 1 and Part 2). Part 1 will evaluate 2 doses of tagraxofusp (9 and 12 micrograms/kilogram/day \[μg/kg/da...
Phase 2
Orlando, Florida, United States and 32 other locations
and clinical activity of SNDX-5613 in combination with intensive chemotherapy in participants with newly diagnosed acute myeloid leukemia (A...
Phase 1
Orlando, Florida, United States and 39 other locations
Researchers are looking for new ways to treat people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). CLL and SL...
Phase 3
Clermont, Florida, United States and 98 other locations
Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess the ...
Phase 3
Orange City, Florida, United States and 69 other locations
(VEN)+ Azacitidine (AZA) works as compared to placebo and VEN+AZA alone for the treatment of participants with newly diagnosed Acute Myeloid Leukemia...
Phase 3
Orlando, Florida, United States and 180 other locations
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