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Find clinical trials for Leukemia in Orlando, FL

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Related conditions:

Myeloid Leukemia
Acute Myeloid Leukemia
Lymphoid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lymphoma
Myelodysplastic Syndromes

Leukemia trials near Orlando, FL, USA:

A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting
Leukemia
Drug: Methotrexate
Drug: Thioguanine

Phase 2

Incyte
Incyte

Orlando, Florida, United States and 110 other locations

of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets CD19 which is located on the leukemia...

Enrolling
Lymphoblastic Leukemia
Drug: Methotrexate
Drug: Ziftomenib

Phase 1, Phase 2

Tanja Andrea Gruber

Orlando, Florida, United States and 24 other locations

Locations recently updated

with azacitidine to improve Overall Survival (OS) in Acute Myeloid Leukemia (AML) participants compared to Best Supportive Care (BSC) when g...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Cancer
Drug: Venetoclax
Drug: Azacitidine

Phase 3

AbbVie
AbbVie

Orlando, Florida, United States and 164 other locations

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orall...

Active, not recruiting
Blastic Phase Chronic Myelogenous Leukemia
Chronic Phase Chronic Myelogenous Leukemia
Drug: Bosutinib

Phase 1, Phase 2

Children's Oncology Group

Orlando, Florida, United States and 44 other locations

The purpose of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL. Participants...

Active, not recruiting
Leukemia, B-cell
Leukemia, Lymphocytic
Drug: Pirtobrutinib
Drug: Ibrutinib

Phase 3

Loxo Oncology
Loxo Oncology

Lakeland, Florida, United States and 179 other locations

and clinical activity of SNDX-5613 in combination with intensive chemotherapy in participants with newly diagnosed acute myeloid leukemia (A...

Enrolling
Acute Myeloid Leukemias
Drug: SNDX-5613
Drug: Chemotherapy Regimen

Phase 1

Syndax Pharmaceuticals
Syndax Pharmaceuticals

Orlando, Florida, United States and 9 other locations

Locations recently updated

Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess the ...

Enrolling
Chronic Lymphocytic Leukemia
Drug: Acalabrutinib
Drug: Obinutuzumab

Phase 3

AbbVie
AbbVie

Orange City, Florida, United States and 26 other locations

The safety run-in part of the study aims to evaluate the safety and tolerability of blinatumomab alternating with low-intensity chemotherapy. The pha...

Enrolling
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Drug: Low-intensity chemotherapy regimen
Drug: Blinatumomab

Phase 3

Amgen
Amgen

Orlando, Florida, United States and 159 other locations

The main aim is to see how the combination of pevonedistat + venetoclax + azacitidine compares to venetoclax + azacitidine in adults recently diagnos...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: Pevonedistat
Drug: Venetoclax

Phase 2

Takeda
Takeda

Orlando, Florida, United States and 56 other locations

chemotherapy in participants with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) negative acute myeloid leukemia...

Enrolling
Leukemia
Drug: Quizartinib
Drug: Placebo

Phase 3

Daiichi Sankyo
Daiichi Sankyo

Kissimmee, Florida, United States and 251 other locations

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