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Find clinical trials for Leukemia in San Diego, CA

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Related conditions:

Myeloid Leukemia
Acute Myeloid Leukemia
Lymphoid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myelodysplastic Syndromes

Leukemia trials near San Diego, CA, USA:

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

in treating pediatric and young adult patients with acute myeloid leukemia (AML) or acute leukemia of ambiguous lineage (ALAL) that...

Enrolling
Refractory Acute Leukemia of Ambiguous Lineage
Acute Myeloid Leukemia, in Relapse
Drug: Methotrexate
Drug: Venetoclax

Phase 1

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

San Diego, California, United States and 10 other locations

pediatric patients with MRD positive CD22-positive B-lymphoblastic leukemia (B-ALL).Some patients with newly diagnosed ALL maintain low leve...

Enrolling
Acute Lymphoblastic Leukemia
Drug: Cytarabine
Drug: Methotrexate

Phase 2

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

San Diego, California, United States and 1 other location

The overarching objective of this study is to use novel precision medicine strategies based on inherited and acquired leukemia-specific geno...

Active, not recruiting
Acute Lymphoblastic Leukemia
Acute Lymphoblastic Lymphoma
Drug: Asparaginase Erwinia chrysanthemi (recombinant)-rywn
Drug: Thioguanine

Phase 2, Phase 3

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

San Diego, California, United States and 7 other locations

in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic syndromes with increased blasts grade 2...

Enrolling
Leukemia, Myeloid, Acute
Chronic Myelomonocytic Leukemia
Drug: Venetoclax Oral Tablet
Drug: Tuspetinib

Phase 1, Phase 2

Aptose Biosciences

La Jolla, California, United States of America and 33 other locations

with relapsed or refractory B-cell acute lymphoblastic leukemia with high bone marrow lymphoblast percentage (\>50% lymphoblasts)....

Active, not recruiting
B-Cell Acute Lymphoblastic Leukemia, Adult
Drug: pembrolizumab
Drug: blinatumomab

Phase 1, Phase 2

University of California San Diego
University of California San Diego

La Jolla, California, United States and 3 other locations

The purpose of the study is to determine whether ibrutinib in combination with GA101 - Obinutuzumab might be useful for the treatment of CLL. This st...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: ibrutinib
Drug: GA101

Phase 1, Phase 2

University of California San Diego
University of California San Diego

La Jolla, California, United States of America

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting
Leukemia
Drug: Methotrexate
Drug: Thioguanine

Phase 2

Incyte
Incyte

San Diego, California, United States and 110 other locations

of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets CD19 which is located on the leukemia...

Enrolling
Lymphoblastic Leukemia
Drug: Methotrexate
Drug: Ziftomenib

Phase 1, Phase 2

Tanja Andrea Gruber

San Diego, California, United States and 24 other locations

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared wi...

Active, not recruiting
Leukemia, Myeloid, Acute
Leukemia, Myelomonocytic, Chronic
Drug: Pevonedistat
Drug: Azacitidine

Phase 3

Takeda
Takeda

La Jolla, California, United States and 240 other locations

This is a Phase 1/2a, multicenter, open-label, first-in-human (FIH) study of VOR33 in participants with AML or MDS who are undergoing human leukocyte...

Enrolling
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes
Drug: Mylotarg
Biological: VOR33

Phase 1, Phase 2

Vor Biopharma

La Jolla, California, United States and 13 other locations

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