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Find clinical trials for Leukemia in San Diego, CA

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Related conditions:

Myeloid Leukemia
Acute Myeloid Leukemia
Lymphoid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myelodysplastic Syndromes

Leukemia trials near San Diego, CA, USA:

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

in treating pediatric and young adult patients with acute myeloid leukemia (AML) or acute leukemia of ambiguous lineage (ALAL) that...

Enrolling
Refractory Acute Leukemia of Ambiguous Lineage
Acute Myeloid Leukemia, in Relapse
Drug: Methotrexate
Drug: Venetoclax

Phase 1

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

San Diego, California, United States and 9 other locations

The overarching objective of this study is to use novel precision medicine strategies based on inherited and acquired leukemia-specific geno...

Active, not recruiting
Acute Lymphoblastic Leukemia
Acute Lymphoblastic Lymphoma
Drug: Asparaginase Erwinia chrysanthemi (recombinant)-rywn
Drug: Thioguanine

Phase 2, Phase 3

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

San Diego, California, United States and 7 other locations

with relapsed or refractory B-cell acute lymphoblastic leukemia with high bone marrow lymphoblast percentage (>50% lymphoblasts)....

Active, not recruiting
B-Cell Acute Lymphoblastic Leukemia, Adult
Drug: pembrolizumab
Drug: blinatumomab

Phase 1, Phase 2

University of California San Diego
University of California San Diego

La Jolla, California, United States and 3 other locations

This study will evaluate the efficacy of uproleselan (GMI-1271), a specific E-selectin antagonist, in combination with chemotherapy to treat relapsed...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Uproleselan
Drug: Placebo

Phase 3

GlycoMimetics

La Jolla, California, United States and 69 other locations

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting
Leukemia
Drug: Cytarabine
Drug: Leucovorin Calcium

Phase 2

Incyte
Incyte

San Diego, California, United States and 110 other locations

The purpose of the study is to determine whether ibrutinib in combination with GA101 - Obinutuzumab might be useful for the treatment of CLL. This st...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: ibrutinib
Drug: GA101

Phase 1, Phase 2

University of California San Diego
University of California San Diego

La Jolla, California, United States of America

This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) or AML secondary to prior m...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Placebo
Drug: Oral Azacitidine

Phase 3

Celgene
Celgene

San Diego, California, United States and 222 other locations

of asciminib versus nilotinib for the treatment of newly diagnosed, previously untreated patients with Positive Chronic Myelogenous Leukemia...

Enrolling
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
Drug: Asciminib
Drug: Nilotinib

Phase 3

Novartis
Novartis

San Diego, California, United States and 134 other locations

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared wi...

Active, not recruiting
Leukemia, Myeloid, Acute
Leukemia, Myelomonocytic, Chronic
Drug: Pevonedistat
Drug: Azacitidine

Phase 3

Takeda
Takeda

La Jolla, California, United States and 240 other locations

Locations recently updated

This is a Phase 1/2a, multicenter, open-label, first-in-human (FIH) study of VOR33 in participants with AML or MDS who are undergoing human leukocyte...

Enrolling
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes
Biological: VOR33
Drug: Mylotarg

Phase 1, Phase 2

Vor Biopharma

La Jolla, California, United States and 10 other locations

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