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pediatric patients with MRD positive CD22-positive B-lymphoblastic leukemia (B-ALL).Some patients with newly diagnosed ALL maintain low leve...
Phase 2
San Diego, California, United States and 1 other location
The overarching objective of this study is to use novel precision medicine strategies based on inherited and acquired leukemia-specific geno...
Phase 2, Phase 3
San Diego, California, United States and 7 other locations
in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic syndromes with increased blasts grade 2...
Phase 1, Phase 2
La Jolla, California, United States of America and 33 other locations
with relapsed or refractory B-cell acute lymphoblastic leukemia with high bone marrow lymphoblast percentage (\>50% lymphoblasts)....
Phase 1, Phase 2
La Jolla, California, United States and 3 other locations
The purpose of the study is to determine whether ibrutinib in combination with GA101 - Obinutuzumab might be useful for the treatment of CLL. This st...
Phase 1, Phase 2
La Jolla, California, United States of America
chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...
Phase 2
San Diego, California, United States and 110 other locations
of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets CD19 which is located on the leukemia...
Phase 1, Phase 2
San Diego, California, United States and 24 other locations
This is a Phase 1/2a, multicenter, open-label, first-in-human (FIH) study of VOR33 in participants with AML or MDS who are undergoing human leukocyte...
Phase 1, Phase 2
La Jolla, California, United States and 14 other locations
Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess retr...
Phase 2
La Jolla, California, United States and 51 other locations
A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic leukemia ...
Phase 3
La Jolla, California, United States and 37 other locations
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