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a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung...
Phase 2
Chapel Hill, North Carolina, United States and 83 other locations
results observed in participants with Extensive-stage Small Cell Lung Cancer (ES-SCLC) who received at least 1 prior line of platin...
Phase 2
Durham, North Carolina, United States of America and 57 other locations
The goal of this Phase 1 clinical study is test tumor infiltrating lymphocytes (known as C-TIL051) with NKTR-255 and anti-PD1 therapy for su ...
Phase 1
Raleigh, North Carolina, United States and 3 other locations
This is a phase 1, single-center, open-label study that enrolls adult subjects with extensive stage lung cancer or stage IV non-sma ...
Early Phase 1
Chapel Hill, North Carolina, United States of America
The main aim of this study is to:* evaluate safety and efficacy (per Response Evaluation Criteria in Solid Tumors version 1.1 \[RECIST 1.1\]...
Phase 2
Durham, North Carolina, United States and 80 other locations
KRAS G12C inhibitors (sotorasib or adagrasib) in participants with KRAS G12C-positive (KRAS G12C +) advanced or metastatic non-small cell lung...
Phase 3
Chapel Hill, North Carolina, United States of America and 200 other locations
overall response rate (ORR) when compared to nivolumab plus PDCT in participants with previously untreated Stage IV or recurrent non-small cell lung...
Phase 2
Durham, North Carolina, United States and 126 other locations
survival compared with carboplatin, etoposide, and nivolumab alone in newly diagnosed participants with extensive-stage small cell lung cancer...
Phase 2
Durham, North Carolina, United States and 38 other locations
Non-Squamous Non-Small Cell Lung Cancer (NSCLC) remains a leading cause of cancer mortality worldwide, with poor survival ...
Phase 2, Phase 3
Greensboro, North Carolina, United States and 60 other locations
This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...
Phase 3
Chapel Hill, North Carolina, United States and 182 other locations
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