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Find clinical trials for Melanoma in Aurora, CO

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Melanoma trials near Aurora, CO, USA:

Neoadjuvant Darovasertib in Primary Uveal Melanoma

This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma...

Enrolling
Uveal Melanoma
Procedure: Primary Local Therapy
Drug: Darovasertib

Phase 3

Ideaya Biosciences

Aurora, Colorado, United States and 86 other locations

The goal of this clinical trial is to understand if a new drug called LNS8801 can safely treat patients with melanoma. The primary question ...

Enrolling
Melanoma Stage IIIB-IV
Melanoma (Skin Cancer)
Biological: Immunotherapy (ipilimumab and nivolumab)
Biological: Immunotherapy (Pembrolizumab)

Phase 2, Phase 3

Linnaeus Therapeutics

Aurora, Colorado, United States and 6 other locations

1/2, open-label study of a modified interleukin-2 fusion protein (IOV 3001) in participants with previously treated, unresectable or metastatic melanoma...

Enrolling
Ocular Melanoma
Metastatic Melanoma
Biological: IOV-3001

Phase 1, Phase 2

Iovance Biotherapeutics

Denver, Colorado, United States and 3 other locations

alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...

Enrolling
Melanoma
Unresectable Melanoma
Biological: Pembrolizumab with Optional Crossover Period
Biological: Lifileucel plus Pembrolizumab

Phase 3

Iovance Biotherapeutics

Aurora, Colorado, United States and 71 other locations

This is a study of transfusion of TBX-3400 in patients with stage III and IV melanoma resistant or refractory to Immune Checkpoint Inhibitor...

Enrolling
Stage III Melanoma
Stage IV Melanoma
Biological: TBX-3400

Phase 1

Taiga Biotechnologies

Denver, Colorado, United States and 1 other location

and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + tram...

Active, not recruiting
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Phase 3

Erasca

Englewood, Colorado, United States and 58 other locations

This study is being done to find the best dose of an investigational drug called NBM-BMX for people with metastatic uveal melanoma, a type o...

Enrolling
Uveal Melanoma, Metastatic
Metastatic Uveal Melanoma
Drug: NBM-BMX Capsule are proprietary products developed by Novelwise Pharmaceutical Corporation (Novelwise) for treatment of patients suffering from cancers.

Phase 1, Phase 2

Novelwise Pharmaceutical

Denver, Colorado, United States and 2 other locations

The study is focused on patients with a type of skin cancer known as melanoma. The aim of the study is to see how safe and effective the com...

Enrolling
Melanoma
Drug: fianlimab
Drug: cemiplimab

Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Aurora, Colorado, United States and 107 other locations

positive previously untreated (1L) untreated metastatic uveal melanoma (mUM) with an integrated circulating tumor DNA (ctDNA) biomarker....

Enrolling
Uveal Melanoma
Drug: Tebentafusp

Phase 2

Diwakar Davar

Aurora, Colorado, United States and 2 other locations

To evaluate the overall survival of HLA-A\*0201 positive adult patients with previously untreated advanced UM receiving IMCgp100 compared to Investig...

Active, not recruiting
Uveal Melanoma
Biological: IMCgp100
Biological: Pembrolizumab

Phase 2

Immunocore
Immunocore

Aurora, Colorado, United States and 56 other locations

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