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Find clinical trials for Melanoma in Barcelona, CT

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Melanoma trials near Barcelona, CT, ESP:

A Randomised Phase II Study of Roginolisib in Patients with Advanced/metastatic Uveal Melanoma (OCULE-01)

The goal of this clinical trial is to learn how roginolisib works in comparison to standard treatment in adult patients with uveal/ocular melanoma...

Enrolling
Ocular Melanoma
Uveal Melanoma
Drug: roginolisib
Drug: Investigator choice of standard therapy

Phase 2

iOnctura

Barcelona, Spain and 15 other locations

alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...

Enrolling
Melanoma
Unresectable Melanoma
Biological: Pembrolizumab with Optional Crossover Period
Biological: Lifileucel plus Pembrolizumab

Phase 3

Iovance Biotherapeutics

Barcelona, Spain and 60 other locations

the efficacy and safety of 12 months of encorafenib in combination with binimetinib in adjuvant setting of BRAF V600E/K mutant stage IIB/C melanoma...

Active, not recruiting
Melanoma
Drug: Placebo to match Encorafenib ; Placebo to match Binimetinib
Drug: Encorafenib and Binimetinib

Phase 3

Pierre Fabre
Pierre Fabre

Barcelona, Spain and 154 other locations

therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma...

Enrolling
Advanced Melanoma
Drug: Tebentafusp with Pembrolizumab
Drug: Tebentafusp

Phase 3

Immunocore
Immunocore

Barcelona, Spain and 65 other locations

medicines (ipilimumab and nivolumab) given for the treatment of melanoma.Melanoma is a type of cancer that starts in the cells that...

Active, not recruiting
Melanoma
Drug: encorafenib
Drug: ipilimumab

Phase 2

Pfizer
Pfizer

Barcelona, Spain and 62 other locations

(PK) similarity and efficacy, safety, and immunogenicity of ABP 206 compared with OPDIVO® (nivolumab) in subjects with resected advanced melanoma...

Active, not recruiting
Melanoma
Drug: EU-authorized Nivolumab
Drug: ABP 206

Phase 3

Amgen
Amgen

Barcelona, Spain and 110 other locations

binimetinib, and pembrolizumab) given together for the treatment of melanoma that:* is advanced or metastatic (spread to other parts of the ...

Active, not recruiting
Melanoma
Drug: Binimetinib
Drug: Encorafenib

Phase 3

Pfizer
Pfizer

Barcelona, Spain and 227 other locations

Recently updated

Brain metastases in patients with advanced and metastatic melanoma are a frequent complication and a significant cause of morbidity and mort...

Not yet enrolling
Melanoma and Brain Metastases
Melanoma BRAF V600E/K Mutated
Drug: cemiplimab+fianlimab
Drug: Encorafenib + Binimetinib

Phase 2

Grupo Español Multidisciplinar de Melanoma

Barcelona, Spain and 17 other locations

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...

Enrolling
Mucosal Melanoma
Cutaneous Melanoma
Drug: Nemvaleukin Alfa Intravenous Less Frequent Dosing
Drug: Pembrolizumab

Phase 2

Mural Oncology

Barcelona, Spain and 43 other locations

and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + tram...

Enrolling
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Phase 3

Erasca

Barcelona, Spain and 58 other locations

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