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Find clinical trials for Melanoma in Birmingham, AL

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Related conditions:

Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
Renal Cell Carcinoma
Lung Cancer
Squamous Cell Carcinoma

Melanoma trials near Birmingham, AL, USA:

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...

Enrolling
Melanoma
Unresectable Melanoma
Biological: Pembrolizumab with Optional Crossover Period
Biological: Lifileucel plus Pembrolizumab

Phase 3

Iovance Biotherapeutics

Birmingham, Alabama, United States and 32 other locations

of ANV419 with anti-PD1 antibody or with anti-CTLA4 antibody in adult participants with advanced (unresectable or metastatic) cutaneous melanoma...

Enrolling
Melanoma (Skin)
Metastatic Melanoma
Drug: Ipilimumab
Drug: ANV419

Phase 1, Phase 2

Anaveon

Birmingham, Alabama, United States and 24 other locations

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Sham Treatment

Phase 3

Aura Biosciences
Aura Biosciences

Birmingham, Alabama, United States and 37 other locations

to assess nivolumab plus relatlimab fixed-dose combination (FDC) versus nivolumab alone in participants with completely resected stage III-IV melanoma...

Active, not recruiting
Melanoma
Biological: Nivolumab
Biological: Nivolumab + Relatlimab Fixed Dose Combination

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Birmingham, Alabama, United States and 171 other locations

and pediatric participants after complete resection of Stage IIB/C melanoma with no evidence of disease (NED) who are at high risk for recur...

Active, not recruiting
Melanoma
Biological: Nivolumab
Other: Placebo

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Birmingham, Alabama, United States and 128 other locations

in patients with locally advanced unresectable or metastatic melanoma with BRAF V600 mutation. A total of approximately 900 patients will be...

Active, not recruiting
Melanoma
Drug: MEK162
Drug: vemurafenib

Phase 3

Pfizer
Pfizer

Birmingham, Alabama, United States and 378 other locations

+ cobimetinib + vemurafenib in patients with previously untreated BRAFv600 mutation-positive metastatic or unresectable locally advanced melanoma...

Active, not recruiting
Melanoma
Drug: Atezolizumab Placebo
Drug: Vemurafenib

Phase 3

Roche
Roche

Birmingham, Alabama, United States and 115 other locations

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...

Enrolling
Non-melanoma Skin Cancer
Melanoma (Skin)
Biological: RP1
Biological: nivolumab

Phase 2

Replimune

Birmingham, Alabama, United States and 52 other locations

This Phase 1b/2a study will assess the efficacy, safety, and pharmacodynamics of CyPep-1 when administered directly into measurable tumor lesions in...

Active, not recruiting
Advanced Melanoma
Advanced Head and Neck Squamous Cell Carcinoma
Drug: Pembrolizumab 25 MG/ML [KEYTRUDA®]
Drug: CyPep-1

Phase 1, Phase 2

Cytovation

Birmingham, Alabama, United States and 24 other locations

The primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected...

Enrolling
Advanced Unresectable Solid Tumor
Metastatic Solid Tumor
Drug: Toripalimab
Drug: TAB004

Phase 1

TopAlliance Biosciences

Birmingham, Alabama, United States and 23 other locations

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