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binimetinib, and pembrolizumab) given together for the treatment of melanoma that:is advanced or metastatic (spread to other parts of the bo...
Phase 3
Cincinnati, Ohio, United States and 227 other locations
Approximately 40 participants with locally advanced or metastatic melanoma will be enrolled in 20 sites in the United States into 1 of the f...
Phase 2
Cincinnati, Ohio, United States and 12 other locations
antigen (HLA)-A*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotini...
Phase 2, Phase 3
Cincinnati, Ohio, United States and 62 other locations
The purpose of this study is to assess the patient's preference for nivolumab subcutaneous (SC) or nivolumab + relatlimab fixed-dose combination (FDC...
Phase 2
Edgewood, Kentucky, United States and 34 other locations
This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 7 other locations
combined with nivolumab on patients with unresectable or metastatic melanoma and eligible patients who are not adolescents or patients with ...
Phase 3
Edgewood, Kentucky, United States and 141 other locations
placebo in participants with surgically resected high-risk Stage II melanoma. Participants in Part 1 will receive either pembrolizumab or pl...
Phase 3
Cincinnati, Ohio, United States and 158 other locations
(GNAQ/11) mutations or PRKC fusions, including metastatic uveal melanoma (MUM), cutaneous melanoma, colorectal cancer, and other so...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 13 other locations
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...
Phase 2
Cincinnati, Ohio, United States and 52 other locations
The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors
Phase 1, Phase 2
Cincinnati, Ohio, United States and 65 other locations
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