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Find clinical trials for Melanoma in Cincinnati, OH

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Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
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Squamous Cell Carcinoma

Melanoma trials near Cincinnati, OH, USA:

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

binimetinib, and pembrolizumab) given together for the treatment of melanoma that:* is advanced or metastatic (spread to other parts of the ...

Active, not recruiting
Melanoma
Drug: Binimetinib
Drug: Encorafenib

Phase 3

Pfizer
Pfizer

Cincinnati, Ohio, United States and 227 other locations

Approximately 40 participants with locally advanced or metastatic melanoma will be enrolled in 20 sites in the United States into 1 of the f...

Active, not recruiting
Locally Advanced Unresectable or Metastatic Melanoma
Drug: Selinexor
Drug: Pembrolizumab

Phase 2

Karyopharm Therapeutics
Karyopharm Therapeutics

Cincinnati, Ohio, United States and 12 other locations

Locations recently updated

antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotin...

Enrolling
Metastatic Uveal Melanoma
Drug: IDE196
Drug: Nivolumab

Phase 2, Phase 3

Ideaya Biosciences

Cincinnati, Ohio, United States and 64 other locations

The purpose of this study is to assess the patient's preference for nivolumab subcutaneous (SC) or nivolumab + relatlimab fixed-dose combination (FDC...

Enrolling
Melanoma
Drug: nivolumab+rHuPH20
Drug: relatlimab+nivolumab+rHuPH20

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Edgewood, Kentucky, United States and 34 other locations

This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma...

Enrolling
Metastatic Melanoma
Unresectable Melanoma
Biological: IOV-4001

Phase 1, Phase 2

Iovance Biotherapeutics

Cincinnati, Ohio, United States and 7 other locations

combined with nivolumab on patients with unresectable or metastatic melanoma and eligible patients who are not adolescents or patients with ...

Enrolling
Unresectable or Metastatic Melanoma
Progressive Brain Metastasis
Drug: Placebo in combination with nivolumab
Drug: HBI-8000 in combination with nivolumab

Phase 3

HUYABIO

Edgewood, Kentucky, United States and 141 other locations

placebo in participants with surgically resected high-risk Stage II melanoma. Participants in Part 1 will receive either pembrolizumab or pl...

Active, not recruiting
Melanoma
Other: Placebo
Biological: Pembrolizumab

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Cincinnati, Ohio, United States and 158 other locations

(GNAQ/11) mutations or PRKC fusions, including metastatic uveal melanoma (MUM), cutaneous melanoma, colorectal cancer, and other so...

Enrolling
Metastatic Uveal Melanoma
Cutaneous Melanoma
Drug: Crizotinib
Drug: IDE196

Phase 1, Phase 2

Ideaya Biosciences

Cincinnati, Ohio, United States and 13 other locations

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...

Enrolling
Non-melanoma Skin Cancer
Melanoma (Skin)
Biological: RP1
Biological: nivolumab

Phase 2

Replimune

Cincinnati, Ohio, United States and 52 other locations

The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors

Enrolling
Melanoma
Non Small Cell Lung Cancer
Biological: PD-1 inhibitor
Biological: CAB-ROR2-ADC

Phase 1, Phase 2

BioAtla

Cincinnati, Ohio, United States and 65 other locations

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