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binimetinib, and pembrolizumab) given together for the treatment of melanoma that:* is advanced or metastatic (spread to other parts of the ...
Phase 3
Cincinnati, Ohio, United States and 227 other locations
cell death protein-1 (PD-1) inhibitor, in patients with metastatic melanomas or advanced solid tumors. Our hypothesis is that restoration of...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 20 other locations
antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotin...
Phase 2, Phase 3
Cincinnati, Ohio, United States and 65 other locations
The purpose of this study is to assess the patient's preference for nivolumab subcutaneous (SC) or nivolumab + relatlimab fixed-dose combination (FDC...
Phase 2
Edgewood, Kentucky, United States and 36 other locations
This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 8 other locations
combined with nivolumab in patients with unresectable or metastatic melanoma. A separate open-label cohort of adults with new, progressive b...
Phase 3
Edgewood, Kentucky, United States and 138 other locations
placebo in participants with surgically resected high-risk Stage II melanoma. Participants in Part 1 will receive either pembrolizumab or pl...
Phase 3
Cincinnati, Ohio, United States and 158 other locations
(GNAQ/11) mutations or PRKC fusions, including metastatic uveal melanoma (MUM), cutaneous melanoma, colorectal cancer, and other so...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 13 other locations
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...
Phase 2
Cincinnati, Ohio, United States and 52 other locations
The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors
Phase 1, Phase 2
Cincinnati, Ohio, United States and 65 other locations
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