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This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma...
Phase 3
Columbus, Ohio, United States and 86 other locations
manner the recurrence-free survival (RFS) of Stage IIIB/C/D melanoma patients with respect to the standard of care (surgery and adjuvant the...
Phase 3
Columbus, Ohio, United States and 36 other locations
therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma...
Phase 3
Columbus, Ohio, United States and 81 other locations
alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...
Phase 3
Columbus, Ohio, United States and 71 other locations
The study is focused on patients with a type of skin cancer known as melanoma. The aim of the study is to see how safe and effective the com...
Phase 3
Columbus, Ohio, United States and 107 other locations
and pembrolizumab in treating patients with stage IIIB-D or stage IV melanoma that has spread to nearby tissue or lymph nodes. Biological th...
Phase 1
Columbus, Ohio, United States
Patients in the study will be treated with Melphalan/HDS and will receive up to 6 total treatments.This study will evaluate the safety and effects of...
Phase 3
Columbus, Ohio, United States and 4 other locations
To evaluate the overall survival of HLA-A\*0201 positive adult patients with previously untreated advanced UM receiving IMCgp100 compared to Investig...
Phase 2
Columbus, Ohio, United States and 56 other locations
use the immune system to recognize and kill cancer cells. The study is focused on participants with a type of skin cancer known as melanoma...
Phase 2
Columbus, Ohio, United States and 103 other locations
of nivolumab and ipilimumab in patients with metastatic uveal melanoma who have not been treated with immune checkpoint inhibitor therapy....
Phase 2, Phase 3
Columbus, Ohio, United States and 30 other locations
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