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Find clinical trials for Melanoma in Houston, TX

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Melanoma trials near Houston, TX, USA:

Neoadjuvant Atezolizumab in Cutaneous Melanoma

cause side effects that delay surgery in participants with cutaneous melanoma that has not spread to other areas of the body (non-metastatic...

Enrolling
Cutaneous Melanoma
Drug: Atezolizumab

Phase 1

The Methodist Hospital Research Institute (TMHRI)
The Methodist Hospital Research Institute (TMHRI)

Houston, Texas, United States

administered in combination with peginterferon alfa-2b to pediatric patients with unresectable Stage III, metastatic, or recurrent cutaneous melanoma...

Active, not recruiting
Malignant Melanoma
Drug: Peginterferon alfa-2b
Drug: Recombinant interferon alfa-2b

Phase 2

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

Houston, Texas, United States and 2 other locations

ATLAS-IT-05 is an open-label, single-arm study in patients with advanced melanoma accessible for injections (cutaneous, subcutaneous, lymph ...

Active, not recruiting
Advanced Melanoma
Combination Product: LTX-315 in combination with pembrolizumab

Phase 2

Lytix Biopharma

Houston, Texas, United States and 9 other locations

therapy per local standard of care (SoC), best supportive care (BSC)) on protocol survivor follow up) in patients with advanced non-ocular melanoma...

Enrolling
Advanced Melanoma
Drug: Tebentafusp with Pembrolizumab
Drug: Tebentafusp

Phase 2, Phase 3

Immunocore
Immunocore

Houston, Texas, United States and 70 other locations

safety, tolerability, and preliminary efficacy of belzupacap sarotalocan for the treatment of primary indeterminate lesions and small choroidal melanoma...

Active, not recruiting
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Device: PDT Laser

Phase 2

Aura Biosciences
Aura Biosciences

Houston, Texas, United States and 21 other locations

binimetinib, and pembrolizumab) given together for the treatment of melanoma that:* is advanced or metastatic (spread to other parts of the ...

Active, not recruiting
Melanoma
Drug: Binimetinib
Drug: Encorafenib

Phase 3

Pfizer
Pfizer

Houston, Texas, United States and 227 other locations

Locations recently updated

and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + tram...

Enrolling
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Phase 3

Erasca

Houston, Texas, United States and 4 other locations

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Sham Treatment

Phase 3

Aura Biosciences
Aura Biosciences

The Woodlands, Texas, United States and 37 other locations

You are being asked to take part in this study because you have advanced melanoma.The goal of this clinical research study is to learn if or...

Active, not recruiting
Melanoma and Other Malignant Neoplasms of Skin
Metastatic Melanoma
Drug: Azacitidine
Drug: Pembrolizumab

Phase 2

M.D. Anderson Cancer Center
M.D. Anderson Cancer Center

Houston, Texas, United States

tolerability, PK and antitumor activities of IN10018 as monotherapy and in combination with cobimetinib in subjects with metastatic uveal melanoma...

Enrolling
Metastatic Melanoma
Drug: Cobimetinib
Biological: Atezolizumab

Phase 1

InxMed

Houston, Texas, United States and 7 other locations

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