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Find clinical trials for Melanoma in Houston, TX

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Melanoma trials near Houston, TX, USA:

Neoadjuvant Atezolizumab in Cutaneous Melanoma

cause side effects that delay surgery in participants with cutaneous melanoma that has not spread to other areas of the body (non-metastatic...

Active, not recruiting
Cutaneous Melanoma
Drug: Atezolizumab

Phase 1

The Methodist Hospital Research Institute (TMHRI)
The Methodist Hospital Research Institute (TMHRI)

Houston, Texas, United States

administered in combination with peginterferon alfa-2b to pediatric patients with unresectable Stage III, metastatic, or recurrent cutaneous melanoma...

Active, not recruiting
Malignant Melanoma
Drug: Peginterferon alfa-2b
Drug: Recombinant interferon alfa-2b

Phase 2

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

Houston, Texas, United States and 2 other locations

This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma...

Enrolling
Uveal Melanoma
Procedure: Primary Local Therapy
Drug: Darovasertib

Phase 3

Ideaya Biosciences

Houston, Texas, United States and 86 other locations

manner the recurrence-free survival (RFS) of Stage IIIB/C/D melanoma patients with respect to the standard of care (surgery and adjuvant the...

Enrolling
Melanoma Stage IIID
Melanoma Stage IIIC
Drug: Adjuvant therapy
Procedure: Surgery

Phase 3

Philogen
Philogen

Houston, Texas, United States and 36 other locations

ipilimumab is a safe and effective treatment that causes few or mild side effects for locally advanced or metastatic, unresectable, refractory melanoma...

Enrolling
Advanced Melanoma
Drug: Fianlimab
Drug: Cemiplimab

Phase 2

Memorial Sloan Kettering Cancer Center (MSK)
Memorial Sloan Kettering Cancer Center (MSK)

Houston, Texas, United States and 10 other locations

therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma...

Enrolling
Advanced Melanoma
Drug: Tebentafusp with Pembrolizumab
Drug: Tebentafusp

Phase 3

Immunocore
Immunocore

Houston, Texas, United States and 81 other locations

cell death protein-1 (PD-1) inhibitor, in patients with metastatic melanomas or advanced solid tumors. Our hypothesis is that restoration of...

Active, not recruiting
Mucosal Melanoma
Melanoma
Drug: Phase 1b: APG-115+pembrolizumab

Phase 1, Phase 2

Ascentage Pharma Group
Ascentage Pharma Group

Houston, Texas, United States and 20 other locations

and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + tram...

Active, not recruiting
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Phase 3

Erasca

Houston, Texas, United States and 58 other locations

The study is focused on patients with a type of skin cancer known as melanoma. The aim of the study is to see how safe and effective the com...

Enrolling
Melanoma
Drug: fianlimab
Drug: cemiplimab

Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Houston, Texas, United States and 107 other locations

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Bel-sar

Phase 3

Aura Biosciences
Aura Biosciences

The Woodlands, Texas, United States and 73 other locations

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