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Find clinical trials for Melanoma in Louisville, KY

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Related conditions:

Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
Renal Cell Carcinoma
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Squamous Cell Carcinoma

Melanoma trials near Louisville, KY, USA:

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...

Enrolling
Melanoma
Unresectable Melanoma
Biological: Pembrolizumab with Optional Crossover Period
Biological: Lifileucel plus Pembrolizumab

Phase 3

Iovance Biotherapeutics

Louisville, Kentucky, United States and 47 other locations

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...

Enrolling
Mucosal Melanoma
Cutaneous Melanoma
Drug: Nemvaleukin Alfa Intravenous Less Frequent Dosing
Drug: Pembrolizumab

Phase 2

Mural Oncology

Louisville, Kentucky, United States and 43 other locations

Prospective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin...

Active, not recruiting
Metastatic Melanoma
Biological: Lifileucel

Phase 2

Iovance Biotherapeutics

Louisville, Kentucky, United States of America and 56 other locations

This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma...

Enrolling
Metastatic Melanoma
Unresectable Melanoma
Biological: IOV-4001

Phase 1, Phase 2

Iovance Biotherapeutics

Louisville, Kentucky, United States and 9 other locations

treatment for patients with unresectable Stage IIIb-IV cutaneous melanoma whose disease progressed on an anti PD-1 and an anti-CTLA-4 contai...

Enrolling
Advanced Melanoma
Biological: Vusolimogene Oderparepvec
Biological: Nivolumab

Phase 3

Replimune

Louisville, Kentucky, United States and 12 other locations

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...

Enrolling
Non-melanoma Skin Cancer
Melanoma (Skin)
Biological: RP1
Biological: nivolumab

Phase 2

Replimune

Louisville, Kentucky, United States and 52 other locations

The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors

Active, not recruiting
Melanoma
Non Small Cell Lung Cancer
Biological: PD-1 inhibitor
Biological: CAB-ROR2-ADC

Phase 1, Phase 2

BioAtla

Louisville, Kentucky, United States and 58 other locations

This is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors.

Enrolling
Melanoma
Metastatic Melanoma
Biological: OBX-115

Phase 1, Phase 2

Obsidian Therapeutics

Louisville, Kentucky, United States of America and 6 other locations

A multicenter trial to investigate TBio-4101, an autologous, neoantigen-selected, tumor-reactive TIL product, in patients with advanced solid maligna...

Enrolling
Cutaneous Melanoma
Uveal Melanoma
Biological: TBio-4101
Drug: Pembrolizumab

Phase 1

Turnstone Biologics

Louisville, Kentucky, United States and 12 other locations

TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...

Enrolling
Cancer
Drug: cetuximab
Drug: FOLFIRI

Phase 1

Tizona Therapeutics

Louisville, Kentucky, United States and 38 other locations

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