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This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...
Phase 2
Louisville, Kentucky, United States and 40 other locations
alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...
Phase 3
Louisville, Kentucky, United States and 32 other locations
Prospective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin...
Phase 2
Louisville, Kentucky, United States of America and 56 other locations
administered to participants with unresectable or metastatic melanoma.The study is divided into two phases: Phase 2 and Phase 3.The primary ...
Phase 2, Phase 3
Louisville, Kentucky, United States and 19 other locations
This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma...
Phase 1, Phase 2
Louisville, Kentucky, United States and 7 other locations
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...
Phase 2
Louisville, Kentucky, United States and 52 other locations
The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors
Phase 1, Phase 2
Louisville, Kentucky, United States and 65 other locations
This is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors.
Phase 1, Phase 2
Louisville, Kentucky, United States and 4 other locations
A multicenter trial to investigate TBio-4101, an autologous, neoantigen-selected, tumor-reactive TIL product, in patients with advanced solid maligna...
Phase 1
Louisville, Kentucky, United States and 9 other locations
This is a Phase 1/2, open-label, non-randomized, 4-part Phase 1 trial to determine the safety profile and identify the maximum tolerated dose (MTD) a...
Phase 1
Louisville, Kentucky, United States and 16 other locations
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