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alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...
Phase 3
Louisville, Kentucky, United States and 53 other locations
This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...
Phase 2
Louisville, Kentucky, United States and 43 other locations
This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma...
Phase 1, Phase 2
Louisville, Kentucky, United States and 9 other locations
treatment for patients with unresectable Stage IIIb-IV cutaneous melanoma whose disease progressed on an anti PD-1 and an anti-CTLA-4 contai...
Phase 3
Louisville, Kentucky, United States and 19 other locations
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...
Phase 2
Louisville, Kentucky, United States and 52 other locations
This is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors.
Phase 1, Phase 2
Louisville, Kentucky, United States of America and 6 other locations
A multicenter trial to investigate TBio-4101, an autologous, neoantigen-selected, tumor-reactive TIL product, in patients with advanced solid maligna...
Phase 1
Louisville, Kentucky, United States and 12 other locations
TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...
Phase 1
Louisville, Kentucky, United States and 38 other locations
A prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL LN-144 (Lifileucel...
Phase 2
Louisville, Kentucky, United States and 44 other locations
Phase 1/2 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of SNS-101, a novel anti VISTA IgG1 monoclonal...
Phase 1, Phase 2
Louisville, Kentucky, United States and 10 other locations
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