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Find clinical trials for Melanoma in Philadelphia, PA

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Melanoma trials near Philadelphia, PA, USA:

Status recently updated

Neoadjuvant Darovasertib in Primary Uveal Melanoma

This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma...

Begins enrollment this month
Enrolling
Uveal Melanoma
Procedure: Primary Local Therapy
Drug: Darovasertib

Phase 3

Ideaya Biosciences

Philadelphia, Pennsylvania, United States and 59 other locations

Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma...

Enrolling
Uveal Melanoma
Drug: Darovasertib

Phase 2

Ideaya Biosciences

Philadelphia, Pennsylvania, United States and 24 other locations

The goal of this clinical trial is to understand if a new drug called LNS8801 can safely treat patients with melanoma. The primary question ...

Enrolling
Melanoma Stage IIIB-IV
Melanoma (Skin Cancer)
Biological: Immunotherapy (ipilimumab and nivolumab)
Biological: Immunotherapy (Pembrolizumab)

Phase 2, Phase 3

Linnaeus Therapeutics

Philadelphia, Pennsylvania, United States and 6 other locations

therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma...

Enrolling
Advanced Melanoma
Drug: Tebentafusp with Pembrolizumab
Drug: Tebentafusp

Phase 3

Immunocore
Immunocore

Philadelphia, Pennsylvania, United States and 71 other locations

alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...

Enrolling
Melanoma
Unresectable Melanoma
Biological: Pembrolizumab with Optional Crossover Period
Biological: Lifileucel plus Pembrolizumab

Phase 3

Iovance Biotherapeutics

Camden, New Jersey, United States of America and 71 other locations

of using hydroxychloroquine (HCQ) in combination with nivolumab and ipilimumab or with nivolumab alone in subjects with advanced/metastatic melanoma...

Enrolling
Melanoma
Drug: Nivolumab
Drug: Hydroxychloroquine

Phase 1, Phase 2

Ravi Amaravadi, MD

Philadelphia, Pennsylvania, United States

cell death protein-1 (PD-1) inhibitor, in patients with metastatic melanomas or advanced solid tumors. Our hypothesis is that restoration of...

Active, not recruiting
Mucosal Melanoma
Melanoma
Drug: Phase 1b: APG-115+pembrolizumab

Phase 1, Phase 2

Ascentage Pharma Group
Ascentage Pharma Group

Philadelphia, Pennsylvania, United States and 20 other locations

The study is focused on patients with a type of skin cancer known as melanoma. The aim of the study is to see how safe and effective the com...

Enrolling
Melanoma
Drug: fianlimab
Drug: cemiplimab

Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Philadelphia, Pennsylvania, United States of America and 100 other locations

This phase II trial studies how well nivolumab works in treating patients with stage IIB-IIC melanoma that can be removed by surgery. Monocl...

Active, not recruiting
Melanoma (Skin)
Biological: Nivolumab

Phase 2

Sidney Kimmel Cancer Center at Thomas Jefferson University

Philadelphia, Pennsylvania, United States and 3 other locations

sub-type 1 receptor (MC1R) is being evaluated as a monotherapy and in combination with Nivolumab in subjects with unresectable and metastatic melanoma...

Enrolling
Mucosal Melanoma
Melanoma Stage IV
Drug: Nivolumab
Drug: [212Pb]VMT01

Phase 1, Phase 2

Perspective Therapeutics

Philadelphia, Pennsylvania, United States of America and 10 other locations

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