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This phase II trial studies how well binimetinib and imatinib work in treating patients with stage III-IV KIT-mutant melanoma that cannot be....
Phase 2
La Jolla, California, United States and 1 other location
administered in combination with peginterferon alfa-2b to pediatric patients with unresectable Stage III, metastatic, or recurrent cutaneous melanoma...
Phase 2
San Diego, California, United States and 2 other locations
Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma...
Phase 2
La Jolla, California, United States and 24 other locations
This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...
Phase 2
La Jolla, California, United States and 43 other locations
efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...
Phase 3
La Jolla, California, United States and 46 other locations
antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotin...
Phase 2, Phase 3
La Jolla, California, United States and 65 other locations
be those with pathological diagnosis of unresectable or metastatic melanoma who are progressing or have progressed on either pembrolizumab o...
Phase 2
La Jolla, California, United States and 32 other locations
manner the recurrence-free survival (RFS) of Stage IIIB/C melanoma patients with respect to the standard of care (surgery and adjuvant thera...
Phase 3
La Jolla, California, United States and 33 other locations
combined with nivolumab in patients with unresectable or metastatic melanoma. A separate open-label cohort of adults with new, progressive b...
Phase 3
La Jolla, California, United States and 138 other locations
treatment compared to pembrolizumab in patients that have had melanoma removal surgery but are still at high risk for the recurrence of the...
Phase 3
La Jolla, California, United States and 206 other locations
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