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Find clinical trials for Melanoma in San Diego, CA

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Melanoma trials near San Diego, CA, USA:

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

This phase II trial studies how well binimetinib and imatinib work in treating patients with stage III-IV KIT-mutant melanoma that cannot be....

Enrolling
Melanoma Stage IV
Melanoma Stage III
Drug: Binimetinib
Drug: Imatinib

Phase 2

University of California San Francisco (UCSF)
University of California San Francisco (UCSF)

La Jolla, California, United States and 1 other location

administered in combination with peginterferon alfa-2b to pediatric patients with unresectable Stage III, metastatic, or recurrent cutaneous melanoma...

Active, not recruiting
Malignant Melanoma
Drug: Peginterferon alfa-2b
Drug: Recombinant interferon alfa-2b

Phase 2

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

San Diego, California, United States and 2 other locations

Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma...

Enrolling
Uveal Melanoma
Drug: Darovasertib

Phase 2

Ideaya Biosciences

La Jolla, California, United States and 24 other locations

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...

Enrolling
Mucosal Melanoma
Cutaneous Melanoma
Drug: Nemvaleukin Alfa Intravenous Less Frequent Dosing
Drug: Pembrolizumab

Phase 2

Mural Oncology

La Jolla, California, United States and 43 other locations

of ANV419 with anti-PD1 antibody or with anti-CTLA4 antibody in adult participants with advanced (unresectable or metastatic) cutaneous melanoma...

Enrolling
Melanoma (Skin)
Metastatic Melanoma
Drug: Ipilimumab
Drug: Pembrolizumab

Phase 1, Phase 2

Anaveon

La Jolla, California, United States and 24 other locations

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Sham Treatment

Phase 3

Aura Biosciences
Aura Biosciences

La Jolla, California, United States and 45 other locations

Prospective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin...

Active, not recruiting
Metastatic Melanoma
Biological: Lifileucel

Phase 2

Iovance Biotherapeutics

La Jolla, California, United States and 56 other locations

antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotin...

Enrolling
Metastatic Uveal Melanoma
Drug: IDE196
Drug: Nivolumab

Phase 2, Phase 3

Ideaya Biosciences

La Jolla, California, United States and 65 other locations

be those with pathological diagnosis of unresectable or metastatic melanoma who are progressing or have progressed on either pembrolizumab o...

Active, not recruiting
Stage III/IV Melanoma
Biological: Pembrolizumab
Biological: tavokinogene telseplasmid

Phase 2

OncoSec Medical

La Jolla, California, United States and 32 other locations

manner the recurrence-free survival (RFS) of Stage IIIB/C melanoma patients with respect to the standard of care (surgery and adjuvant thera...

Enrolling
Melanoma Stage IIIB/C
Procedure: Surgery
Drug: Daromun

Phase 3

Philogen
Philogen

La Jolla, California, United States and 33 other locations

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