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Find clinical trials for Melanoma in San Francisco, CA

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Melanoma trials near San Francisco, CA, USA:

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

This phase II trial studies how well binimetinib and imatinib work in treating patients with stage III-IV KIT-mutant melanoma that cannot be....

Enrolling
Melanoma Stage IV
Melanoma Stage III
Drug: Binimetinib
Drug: Imatinib

Phase 2

University of California San Francisco (UCSF)
University of California San Francisco (UCSF)

San Francisco, California, United States and 1 other location

Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma...

Enrolling
Uveal Melanoma
Drug: Darovasertib

Phase 2

Ideaya Biosciences

Palo Alto, California, United States and 24 other locations

ipilimumab is a safe and effective treatment that causes few or mild side effects for locally advanced or metastatic, unresectable, refractory melanoma...

Enrolling
Advanced Melanoma
Drug: Fianlimab
Drug: Cemiplimab

Phase 2

Memorial Sloan Kettering Cancer Center (MSK)
Memorial Sloan Kettering Cancer Center (MSK)

Stanford, California, United States and 9 other locations

alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...

Enrolling
Melanoma
Unresectable Melanoma
Biological: Pembrolizumab with Optional Crossover Period
Biological: Lifileucel plus Pembrolizumab

Phase 3

Iovance Biotherapeutics

San Francisco, California, United States and 53 other locations

and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + tram...

Enrolling
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Phase 3

Erasca

San Francisco, California, United States and 58 other locations

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Bel-sar

Phase 3

Aura Biosciences
Aura Biosciences

Palo Alto, California, United States and 46 other locations

participants with a type of skin cancer known as melanoma.The objective of this study is to see if the combination of fianlimab and cemipli...

Enrolling
Melanoma
Drug: pembrolizumab
Drug: cemiplimab

Phase 2, Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

San Francisco, California, United States and 12 other locations

Patients in the study will be treated with Melphalan/HDS and will receive up to 6 total treatments.This study will evaluate the safety and effects of...

Active, not recruiting
Metastatic Uveal Melanoma
Metastatic Ocular Melanoma
Combination Product: Melphalan (3 mg/kg IBW) with Hepatic Delivery System (HDS)

Phase 3

Delcath Systems

Palo Alto, California, United States and 4 other locations

To evaluate the overall survival of HLA-A\*0201 positive adult patients with previously untreated advanced UM receiving IMCgp100 compared to Investig...

Active, not recruiting
Uveal Melanoma
Biological: IMCgp100
Biological: Pembrolizumab

Phase 2

Immunocore
Immunocore

San Francisco, California, United States and 55 other locations

of ceralasertib, when administered as monotherapy and in combination with durvalumab in participants with unresectable or advanced melanoma ...

Active, not recruiting
Melanoma
Biological: Durvalumab
Drug: Ceralasertib

Phase 2

AstraZeneca
AstraZeneca

San Francisco, California, United States and 65 other locations

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