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Find clinical trials for Melanoma in Tampa, FL

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Squamous Cell Carcinoma

Melanoma trials near Tampa, FL, USA:

Study of Trametinib + Ceritinib in Patients With Unresectable Melanoma

the risks and benefits of ceritinib (ZYKADIA) given in combination with trametinib (MEKINIST) in patients who have progressed on prior melanoma...

Active, not recruiting
Advanced Melanoma
Melanoma
Drug: Trametinib
Drug: Ceritinib

Phase 1

H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute

Tampa, Florida, United States

The purpose of this study is to determine if neoadjuvant (treatment before surgery) immunotherapy treatment based on tumor biomarkers results in bett...

Enrolling
Melanoma
Advanced Melanoma
Drug: Nivolumab
Drug: Ipilimumab

Phase 2

H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute

Tampa, Florida, United States

The goal of this clinical research study is to find out if taking axitinib with ipilimumab is effective in treating advanced melanoma....

Enrolling
Melanoma
Drug: Ipilimumab
Drug: Axitinib

Phase 2

H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute

Tampa, Florida, United States

receiving a lymphodepleting chemotherapy regimen and before receiving interleukin-2 (IL-2) in participants with unresectable or metastatic melanoma...

Enrolling
Mucosal Melanoma
Non-Cutaneous Melanoma
Drug: Interleukin-2
Drug: Cyclophosphamide

Phase 1

H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute

Tampa, Florida, United States

The primary aim of the study is to establish the maximum-tolerated dose (MTD) of 225Ac-MTI-201 in participants with metastatic uveal melanoma...

Enrolling
Uveal Melanoma
Metastatic
Drug: 1327 microCi of 225Ac-MTI-201
Drug: 564 microCi of 225Ac-MTI-201

Phase 1

Modulation Therapeutics

Tampa, Florida, United States

Recently updated

vemurafenib plus cobimetinib in participants with BRAF V600 mutated melanoma and to evaluate the safety and tolerability of this combination....

Active, not recruiting
Melanoma
Skin Cancer
Drug: XL888
Drug: Cobimetinib

Phase 1

H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute

Tampa, Florida, United States

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Bel-sar

Phase 3

Aura Biosciences
Aura Biosciences

Tampa, Florida, United States and 49 other locations

Prospective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin...

Active, not recruiting
Metastatic Melanoma
Biological: Lifileucel

Phase 2

Iovance Biotherapeutics

Tampa, Florida, United States and 56 other locations

antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotin...

Enrolling
Metastatic Uveal Melanoma
Drug: IDE196
Drug: Nivolumab

Phase 2, Phase 3

Ideaya Biosciences

Tampa, Florida, United States and 65 other locations

Patients in the study will be treated with Melphalan/HDS and will receive up to 6 total treatments.This study will evaluate the safety and effects of...

Active, not recruiting
Metastatic Uveal Melanoma
Metastatic Ocular Melanoma
Combination Product: Melphalan (3 mg/kg IBW) with Hepatic Delivery System (HDS)

Phase 3

Delcath Systems

Tampa, Florida, United States and 4 other locations

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