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Find clinical trials for Multiple Sclerosis (MS) in Charlotte, NC

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Related conditions:

Sclerosis
Multiple Sclerosis
Relapsing-Remitting Multiple Sclerosis
Chronic Progressive Multiple Sclerosis
Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Muscle Spasticity

Multiple Sclerosis (MS) trials near Charlotte, NC, USA:

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation (SOSTOS)

This study will evaluate if relapsing-remitting MS patients that have not had a relapse in the past year would benefit from a switch to ofat...

Enrolling
Relapsing-Remitting Multiple Sclerosis
Drug: Disease modifying treatment (DMT)
Drug: Ofatumumab

Phase 4

Novartis
Novartis

Charlotte, North Carolina, United States and 33 other locations

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...

Enrolling
Relapsing Multiple Sclerosis
Drug: Teriflunomide
Drug: Remibrutinib

Phase 3

Novartis
Novartis

Charlotte, North Carolina, United States and 208 other locations

Recently updated

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...

Enrolling
Relapsing Multiple Sclerosis
Drug: Remibrutinib
Drug: Teriflunomide

Phase 3

Novartis
Novartis

Charlotte, North Carolina, United States and 229 other locations

for the overall conduct of the study at the site, confirmation of subject eligibility, routine study subject clinical management including for MS...

Active, not recruiting
Multiple Sclerosis
Drug: RPC-1063

Phase 3

Celgene
Celgene

Mooresville, North Carolina, United States and 60 other locations

(IV) infusion of ocrelizumab in patients with either relapsing multiple sclerosis (RMS) or primary progressive multiple sc...

Active, not recruiting
Primary Progressive Multiple Sclerosis
Relapsing Multiple Sclerosis
Drug: Ocrelizumab SC
Drug: Dexamethasone given orally

Phase 3

Roche
Roche

Hickory, North Carolina, United States and 37 other locations

Primary Objective:To determine the efficacy of SAR441344 as measured by reduction of the number of new active brain lesionsSecondary Objective:* To e...

Active, not recruiting
Multiple Sclerosis
Drug: MRI contrast-enhancing preparations
Drug: SAR441344 IV

Phase 2

Sanofi
Sanofi

Charlotte, North Carolina, United States and 37 other locations

Locations recently updated

in male and female participants with relapsing forms of multiple sclerosis (aged 18 to 55 years at the time of enrollment). People ...

Enrolling
Multiple Sclerosis
Drug: Activated charcoal
Drug: Cholestyramine

Phase 3

Sanofi
Sanofi

Charlotte, North Carolina, United States and 69 other locations

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the dis...

Enrolling
Multiple Sclerosis
Drug: Frexalimab
Drug: Placebo

Phase 3

Sanofi
Sanofi

Charlotte, North Carolina, United States and 53 other locations

relapse rate (ARR) in participants with relapsing forms of MSSecondary Objective:To assess efficacy of SAR442168 compared to teriflunomide (...

Active, not recruiting
Relapsing Multiple Sclerosis
Drug: Placebo to match Teriflunomide
Drug: Teriflunomide HMR1726

Phase 3

Sanofi
Sanofi

Charlotte, North Carolina, United States and 185 other locations

A study to evaluate the efficacy and safety of fenebrutinib on disability progression in adult participants with Primary Progressive Multiple...

Active, not recruiting
Multiple Sclerosis, Primary Progressive
Drug: Placebo matched to ocrelizumab
Drug: Fenebrutinib

Phase 3

Roche
Roche

Charlotte, North Carolina, United States and 192 other locations

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