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Find clinical trials for Multiple Sclerosis (MS) in Los Angeles, CA

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Related conditions:

Multiple Sclerosis
Chronic Progressive Multiple Sclerosis
Sclerosis
Relapsing-Remitting Multiple Sclerosis
Autoimmune Diseases
Recurrence
Cognitive Dysfunction

Multiple Sclerosis (MS) trials near Los Angeles, CA, USA:

Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis (NEOS)

Efficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosis...

Active, not recruiting
Multiple Sclerosis (MS)
Other: Ofatumumab placebo
Drug: Siponimod

Phase 3

Novartis
Novartis

Los Angeles, California, United States and 50 other locations

To evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS...

Active, not recruiting
Multiple Sclerosis
Drug: Interferon beta-1a
Drug: Placebo capsule

Phase 3

Novartis
Novartis

Los Angeles, California, United States and 72 other locations

This study aims to examine the efficacy and safety of obexelimab in participants with relapsing multiple sclerosis...

Active, not recruiting
Relapsing Multiple Sclerosis
Drug: Placebo
Drug: Obexelimab

Phase 2

Zenas BioPharma

West Hollywood, California, United States and 46 other locations

This study will evaluate if relapsing-remitting MS patients that have not had a relapse in the past year would benefit from a switch to ofat...

Active, not recruiting
Relapsing-Remitting Multiple Sclerosis
Drug: Disease modifying treatment (DMT)
Drug: Ofatumumab

Phase 4

Novartis
Novartis

Torrance, California, United States and 42 other locations

The purpose of this study is to provide efficacy and safety data for remibrutinib in patients with secondary progressive multiple sclerosis...

Enrolling
Secondary Progressive Multiple Sclerosis (SPMS)
Drug: Remibrutinib (blinded)
Drug: Placebo

Phase 3

Novartis
Novartis

West Hollywood, California, United States and 36 other locations

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...

Active, not recruiting
Relapsing Multiple Sclerosis
Drug: Teriflunomide
Drug: Remibrutinib

Phase 3

Novartis
Novartis

Glendale, California, United States and 201 other locations

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...

Active, not recruiting
Relapsing Multiple Sclerosis
Drug: Remibrutinib
Drug: Teriflunomide

Phase 3

Novartis
Novartis

Los Angeles, California, United States and 228 other locations

Locations recently updated

of frexalimab q4w in male and female participants with RMS and nrSPMS (aged 18 to 60 years at the time of enrollment). People diagnosed with MS...

Enrolling
Multiple Sclerosis
Drug: Frexalimab
Drug: MRI contrast-enhancing preparations

Phase 3

Sanofi
Sanofi

West Hollywood, California, United States and 8 other locations

) neo-antigen in subjects with relapsing multiple sclerosis (RMS).COVID-19 sub-study:The purpose of this research sub-study is to e...

Active, not recruiting
Relapsing Multiple Sclerosis
Biological: 23-valent pneumococcal polysaccharide vaccine (23-PPV)
Biological: Tetanus toxoid (TT) containing vaccine (Td, Tdap)

Phase 3

Novartis
Novartis

Fullerton, California, United States and 298 other locations

This is a Phase 3 extension, global, multicenter study to assess the long-term safety and tolerability of tolebrutinib in adult participants (aged ≥1...

Active, not recruiting
Secondary Progressive Multiple Sclerosis
Relapsing Multiple Sclerosis
Drug: Teriflunomide
Drug: Placebo

Phase 3

Sanofi
Sanofi

Los Angeles, California, United States and 352 other locations

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