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cancer). This Phase III trial builds on the efficacy and safety data reported in the previous Phase II VIRO-15 trial with promising objecti ...
Phase 3
Charlotte, North Carolina, United States and 25 other locations
Olaparib Monotherapy in Patients with BRCA Mutated Ovarian Cancer following First Line Platinum Based Chemotherapy....
Phase 3
Charlotte, North Carolina, United States and 176 other locations
This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...
Phase 3
Charlotte, North Carolina, United States and 63 other locations
Ovarian cancer is a heterogeneous disease, characterized by complex molecular and genetic changes. The high expression of vascular ...
Phase 3
Charlotte, North Carolina, United States and 202 other locations
PK, and PD of SON-DP in participants with relapsed/refractory/intolerant to standard of care therapies, for advanced/ metastatic solid tumors...
Phase 1
Huntersville, North Carolina, United States of America and 4 other locations
survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by the investigator. The hypotheses are that pembro...
Phase 3
Charlotte, North Carolina, United States and 186 other locations
treatments in patients with persistent or recurrent rare epithelial ovarian, fallopian tube, or primary peritoneal tumors. Enrollme...
Phase 2
Charlotte, North Carolina, United States and 53 other locations
Dose (RP2D) in patients with ovarian cancer, and Part C will evaluate combination treatment of INX-315 plus a CDK4/6i and selectiv...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 6 other locations
(with enzalutamide-naïve metastatic castration-resistant prostate cancer) will be randomized to receive either NUV-868 monotherapy, enzaluta...
Phase 1, Phase 2
Huntersville, North Carolina, United States of America and 30 other locations
of CPO-100 administered intravenously in cycles of 3 weekly doses with 1 week rest (1 cycle = 4 weeks) in adult patients with advanced solid tumors...
Phase 1
Huntersville, North Carolina, United States of America and 7 other locations
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