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Find clinical trials for Ovarian Cancer in Charlotte, NC

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Related conditions:

Ovarian Epithelial Carcinoma
Cancer
Carcinoma
Endometrial Cancer
Fallopian Tube Cancer
Breast Cancer
Triple Negative Breast Cancer

Ovarian Cancer trials near Charlotte, NC, USA:

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

cancer). This Phase III trial builds on the efficacy and safety data reported in the previous Phase II VIRO-15 trial with promising objecti ...

Enrolling
Primary Peritoneal Cancer
Platinum-refractory Ovarian Cancer
Drug: Non-platinum chemotherapy: Physician's Choice of gemcitabine, taxane (paclitaxel, docetaxel or nab-paclitaxel) or pegylated liposomal doxorubicin
Drug: Platinum chemotherapy: carboplatin (preferred) or cisplatin

Phase 3

Genelux

Charlotte, North Carolina, United States and 23 other locations

Olaparib Monotherapy in Patients with BRCA Mutated Ovarian Cancer following First Line Platinum Based Chemotherapy....

Active, not recruiting
Advanced Ovarian Cancer
FIGO Stage III-IV
Drug: Olaparib 300mg tablets

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 176 other locations

Locations recently updated

This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...

Enrolling
Low Grade Serous Ovarian Cancer
Drug: Defactinib
Drug: Letrozole

Phase 3

Verastem

Charlotte, North Carolina, United States and 50 other locations

Ovarian cancer is a heterogeneous disease, characterized by complex molecular and genetic changes. The high expression of vascular ...

Active, not recruiting
Ovarian Neoplasms
Ovarian, Fallopian Tube and Primary Peritoneal Carcinoma
Drug: Dostarlimab-Placebo
Drug: Standard of care

Phase 3

Tesaro
Tesaro

Charlotte, North Carolina, United States and 202 other locations

PK, and PD of SON-DP in participants with relapsed/refractory/intolerant to standard of care therapies, for advanced/ metastatic solid tumors...

Enrolling
Solid Tumor
Breast Cancer
Drug: SON-DP

Phase 1

Qurgen

Huntersville, North Carolina, United States of America and 4 other locations

survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by the investigator. The hypotheses are that pembro...

Active, not recruiting
Carcinoma, Ovarian Epithelial
Fallopian Tube Neoplasms
Drug: Bevacizumab
Biological: Pembrolizumab

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Charlotte, North Carolina, United States and 186 other locations

treatments in patients with persistent or recurrent rare epithelial ovarian, fallopian tube, or primary peritoneal tumors. Enrollme...

Active, not recruiting
Ovarian Cancer
Drug: Giredestrant
Drug: Cyclophosphamide

Phase 2

Roche
Roche

Charlotte, North Carolina, United States and 53 other locations

Dose (RP2D) in patients with ovarian cancer, and Part C will evaluate combination treatment of INX-315 plus a CDK4/6i and selectiv...

Enrolling
Metastatic Cancer
Advanced Cancer
Drug: INX-315
Drug: Fulvestrant

Phase 1, Phase 2

Incyclix Bio

Charlotte, North Carolina, United States and 6 other locations

(with enzalutamide-naïve metastatic castration-resistant prostate cancer) will be randomized to receive either NUV-868 monotherapy, enzaluta...

Enrolling
Prostate Neoplasm
Advanced Solid Tumor
Drug: Enzalutamide
Drug: NUV-868

Phase 1, Phase 2

Nuvation Bio

Huntersville, North Carolina, United States of America and 30 other locations

of CPO-100 administered intravenously in cycles of 3 weekly doses with 1 week rest (1 cycle = 4 weeks) in adult patients with advanced solid tumors...

Active, not recruiting
Solid Tumor
Drug: CPO-100

Phase 1

Conjupro Biotherapeutics

Huntersville, North Carolina, United States of America and 7 other locations

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