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Find clinical trials for Ovarian Cancer in Charlotte, NC

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Related conditions:

Ovarian Epithelial Carcinoma
Endometrial Cancer
Cancer
Breast Cancer
Fallopian Tube Cancer
Non-Small-Cell Lung Carcinoma
Triple Negative Breast Cancer

Ovarian Cancer trials near Charlotte, NC, USA:

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer (MAIA-ovarian)

The goal of this clinical trial is to learn if the experimental antibody COM701 delays the progression of ovarian cancer in partici ...

Enrolling
Ovarian Cancer
Ovarian Cancer Recurrent
Drug: Normal Saline
Drug: COM701

Phase 1, Phase 2

Compugen

Charlotte, North Carolina, United States and 27 other locations

cancer). This Phase III trial builds on the efficacy and safety data reported in the previous Phase II VIRO-15 trial with promising objecti ...

Enrolling
Primary Peritoneal Cancer
Platinum-refractory Ovarian Cancer
Drug: Non-platinum chemotherapy: Physician's Choice of gemcitabine, taxane (paclitaxel, docetaxel or nab-paclitaxel) or pegylated liposomal doxorubicin
Drug: Platinum chemotherapy: carboplatin (preferred) or cisplatin

Phase 3

Genelux

Charlotte, North Carolina, United States and 30 other locations

Olaparib Monotherapy in Patients with BRCA Mutated Ovarian Cancer following First Line Platinum Based Chemotherapy....

Active, not recruiting
Advanced Ovarian Cancer
FIGO Stage III-IV
Drug: Olaparib 300mg tablets

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 176 other locations

This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...

Enrolling
Low Grade Serous Ovarian Cancer
Drug: Defactinib
Drug: Letrozole

Phase 3

Verastem

Charlotte, North Carolina, United States and 105 other locations

Ovarian cancer is a heterogeneous disease, characterized by complex molecular and genetic changes. The high expression of vascular ...

Active, not recruiting
Ovarian Neoplasms
Ovarian, Fallopian Tube and Primary Peritoneal Carcinoma
Drug: Dostarlimab-Placebo
Drug: Standard of care

Phase 3

Tesaro
Tesaro

Charlotte, North Carolina, United States and 181 other locations

Locations recently updated

The purpose of this study is to evaluate INCB123667 versus investigator's choice of chemotherapy in participants with platinum-resistant ovarian...

Enrolling
Ovarian Cancer
Drug: INCB123667
Drug: Investigator's choice of chemotherapy

Phase 3

Incyte
Incyte

Charlotte, North Carolina, United States and 132 other locations

part has 2 phases, Phase 1a (dose escalation) and Phase 1b (dose expansion). Enrollment to Part A (Phase 1a and Phase 1b) will include ovarian...

Enrolling
Endometrial Cancer
Platinum Resistant Ovarian Cancer
Drug: HWK-016, MUCIN-16-targeted ADC
Drug: Bevacizumab

Phase 1

Whitehawk Therapeutics, Inc.

Charlotte, North Carolina, United States and 11 other locations

PK, and PD of SON-DP in participants with relapsed/refractory/intolerant to standard of care therapies, for advanced/ metastatic solid tumors...

Enrolling
Solid Tumor
Breast Cancer
Drug: SON-DP

Phase 1

Qurgen

Huntersville, North Carolina, United States of America and 4 other locations

T cell therapy product genetically engineered to express an HLA-A\*02:01-restricted T cell receptor (TCR), targeting TP53 R175H mutant solid tumors...

Enrolling
Other Solid Tumors
Breast Cancer
Biological: Autologous, engineered T Cells targeting TP53 R175H

Phase 1

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 17 other locations

survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by the investigator. The hypotheses are that pembro...

Active, not recruiting
Carcinoma, Ovarian Epithelial
Fallopian Tube Neoplasms
Drug: Paclitaxel
Drug: Bevacizumab

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Charlotte, North Carolina, United States and 187 other locations

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