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This research study is studying a combination of interventions as a possible treatment for pancreatic tumor.The interventions invol...
Phase 2
Aurora, Colorado, United States and 9 other locations
phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...
Phase 1
Aurora, Colorado, United States and 68 other locations
The purpose of this study is to find out if an experimental drug will prevent metastatic pancreatic adenocarcinoma from becoming resistant t...
Phase 2
Aurora, Colorado, United States and 2 other locations
evaluate the efficacy, safety, and tolerability of futibatinib in combination with PD-1 antibody-based SoC therapy in adult patients with solid tumors...
Phase 2
Denver, Colorado, United States and 21 other locations
The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma whic...
Phase 3
Denver, Colorado, United States and 40 other locations
The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.
Phase 3
Aurora, Colorado, United States and 24 other locations
to participants. Part C will use the information from Parts A and B to see if PF-08046049/SGN-BB228 is safe and if it works to treat solid tumor...
Phase 1
Denver, Colorado, United States and 43 other locations
This study is open to adults with advanced pancreatic cancer for whom previous treatment was not successful or no treatment exists. ...
Phase 1
Denver, Colorado, United States and 8 other locations
administered orally as monotherapy in patients with advanced solid tumors with gene alterations in the RAS- MAPK pathway for whom there are ...
Phase 1
Denver, Colorado, United States and 7 other locations
This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors th...
Phase 2
Aurora, Colorado, United States and 109 other locations
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