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with either gemcitabine plus nab-paclitaxel (G/NP) or FOLFIRINOX in the treatment of participants with locally advanced, unresectable pancreatic...
Phase 3
Cincinnati, Ohio, United States and 89 other locations
Study of NGM120 in subjects with advanced solid tumors and and pancreatic cancer (Part 1 and 2) and metastatic castration resistant...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 21 other locations
compared to just chemotherapy alone in participants with metastatic pancreatic cancer. One group of participants will only receive ...
Phase 2
Cincinnati, Ohio, United States and 35 other locations
This study is to evaluate the safety and tolerability of RMC-9805 in adults with KRAS G12D-mutant solid tumors.
Phase 1
Cincinnati, Ohio, United States and 6 other locations
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Phase 1
Cincinnati, Ohio, United States and 14 other locations
The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...
Phase 2
Cincinnati, Ohio, United States and 79 other locations
This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 97 other locations
as single agent and in combination with pembrolizumab in participants with advanced or metastatic solid tumors and non-small cell lung cancers...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 36 other locations
and nab-paclitaxel, for front line treatment of locally-advanced pancreatic adenocarcinoma.The device is an experimental, portable, battery ...
Phase 3
Edgewood, Kentucky, United States and 197 other locations
(mFOLFIRINOX) versus mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior sys...
Phase 2
Cincinnati, Ohio, United States and 21 other locations
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