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phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...
Phase 1
Cleveland, Ohio, United States and 55 other locations
SOT102 administered as monotherapy (Part C) and in combination with first-line SoC treatment (Part D) in patients with advanced or metastatic pancreatic...
Phase 1, Phase 2
Cleveland, Ohio, United States and 7 other locations
This is a Phase 1b/2, open-label, multi-center, competitive enrollment and dose-escalation study of HCW9218 in patients with advanced/metastatic pancreatic...
Phase 1, Phase 2
Cleveland, Ohio, United States and 4 other locations
This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder. This is a study for people for ...
Phase 2
Cleveland, Ohio, United States and 42 other locations
as PK and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in subjects with advanced solid tumors...
Phase 1
Cleveland, Ohio, United States and 11 other locations
and antitumor activity of CUE-102 intravenous (IV) monotherapy in HLA-A\*0201 positive patients with WT1 positive recurrent/metastatic solid tumors...
Phase 1
Cleveland, Ohio, United States and 14 other locations
patients with lymphoma, chronic lymphocytic leukemia, or solid tumors with liver dysfunction. Romidepsin may stop the growth of cancer...
Phase 1
Cleveland, Ohio, United States and 11 other locations
targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors...
Phase 1
Cleveland, Ohio, United States and 18 other locations
to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...
Phase 1
Cleveland, Ohio, United States and 23 other locations
The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and exploratory dose response of paltusotine treatment in subjects with c...
Phase 2
Cleveland, Ohio, United States and 34 other locations
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