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of borderline-resectable, locally-advanced , or medically inoperable pancreatic adenocarcinoma will translate into a decreased toxicity. The...
Cleveland, Ohio, United States and 1 other location
This phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread...
Phase 2
Cleveland, Ohio, United States and 70 other locations
phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...
Phase 1
Cleveland, Ohio, United States and 76 other locations
This is a Phase 1b/2, open-label, multi-center, competitive enrollment and dose-escalation study of HCW9218 in patients with advanced/metastatic pancreatic...
Phase 1, Phase 2
Cleveland, Ohio, United States and 4 other locations
(PK) and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in participants with advanced solid tumors...
Phase 1
Cleveland, Ohio, United States and 15 other locations
to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...
Phase 1
Cleveland, Ohio, United States and 57 other locations
The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...
Phase 3
Cleveland, Ohio, United States and 124 other locations
2 mutations. These include tumors in the colon or rectum, the uterus and the cervix (lower part of the uterus), the breast, the bladder, and...
Phase 2
Cleveland, Ohio, United States and 55 other locations
targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors...
Phase 1
Cleveland, Ohio, United States and 19 other locations
evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...
Phase 1, Phase 2
Cleveland, Ohio, United States and 231 other locations
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