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Find clinical trials for Pancreatic Cancer in Cleveland, OH

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Adenocarcinoma
Colorectal Cancer
Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Carcinoma
Ovarian Cancer

Pancreatic Cancer trials near Cleveland, OH, USA:

Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach (ARTIA-Pancreas)

of borderline-resectable, locally-advanced , or medically inoperable pancreatic adenocarcinoma will translate into a decreased toxicity. The...

Enrolling
Pancreatic Cancer
Radiation: Daily Adaptive External Beam Radiation Therapy
Varian

Cleveland, Ohio, United States and 1 other location

This phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread...

Enrolling
Metastatic Pancreatic Carcinoma
Stage IV Pancreatic Cancer AJCC v8
Drug: Pemigatinib
Procedure: Bone Scan

Phase 2

Sameek Roychowdhury

Cleveland, Ohio, United States and 70 other locations

phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...

Enrolling
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: AMG 193
Drug: Gemcitabine

Phase 1

Amgen
Amgen

Cleveland, Ohio, United States and 76 other locations

This is a Phase 1b/2, open-label, multi-center, competitive enrollment and dose-escalation study of HCW9218 in patients with advanced/metastatic pancreatic...

Active, not recruiting
Advanced Pancreatic Carcinoma
Drug: HCW9218

Phase 1, Phase 2

ImmunityBio
ImmunityBio

Cleveland, Ohio, United States and 4 other locations

(PK) and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in participants with advanced solid tumors...

Enrolling
Advanced Solid Tumor
Drug: Olaparib
Drug: XL309

Phase 1

Exelixis
Exelixis

Cleveland, Ohio, United States and 15 other locations

to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...

Enrolling
Advanced Solid Tumor
Non-small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Cleveland, Ohio, United States and 57 other locations

The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Cleveland, Ohio, United States and 124 other locations

2 mutations. These include tumors in the colon or rectum, the uterus and the cervix (lower part of the uterus), the breast, the bladder, and...

Enrolling
Advanced Solid Tumors
HER2 Mutation
Drug: BAY2927088

Phase 2

Bayer
Bayer

Cleveland, Ohio, United States and 55 other locations

targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors...

Enrolling
Epithelial Ovarian Cancer
Pancreas Cancer
Drug: BCA101
Drug: Pembrolizumab

Phase 1

Bicara Therapeutics
Bicara Therapeutics

Cleveland, Ohio, United States and 19 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Cleveland, Ohio, United States and 231 other locations

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