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Find clinical trials for Pancreatic Cancer in Cleveland, OH

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Cleveland, OH, USA:

A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion

phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...

Enrolling
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: Gemcitabine
Drug: AMG 193

Phase 1

Amgen
Amgen

Cleveland, Ohio, United States and 55 other locations

SOT102 administered as monotherapy (Part C) and in combination with first-line SoC treatment (Part D) in patients with advanced or metastatic pancreatic...

Enrolling
Pancreatic Cancer
Drug: SOT102

Phase 1, Phase 2

SOTIO
SOTIO

Cleveland, Ohio, United States and 7 other locations

This is a Phase 1b/2, open-label, multi-center, competitive enrollment and dose-escalation study of HCW9218 in patients with advanced/metastatic pancreatic...

Active, not recruiting
Advanced Pancreatic Carcinoma
Drug: HCW9218

Phase 1, Phase 2

ImmunityBio
ImmunityBio

Cleveland, Ohio, United States and 4 other locations

This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder. This is a study for people for ...

Active, not recruiting
Lung Neoplasms
Bladder Cancer
Drug: brigimadlin

Phase 2

Boehringer Ingelheim
Boehringer Ingelheim

Cleveland, Ohio, United States and 42 other locations

as PK and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in subjects with advanced solid tumors...

Enrolling
Advanced Solid Tumor
Drug: Olaparib
Drug: XL309 (ISM3091)

Phase 1

Exelixis
Exelixis

Cleveland, Ohio, United States and 11 other locations

and antitumor activity of CUE-102 intravenous (IV) monotherapy in HLA-A\*0201 positive patients with WT1 positive recurrent/metastatic solid tumors...

Active, not recruiting
Gastric Cancer
Ovarian Cancer
Drug: CUE-102

Phase 1

Cue Biopharma

Cleveland, Ohio, United States and 14 other locations

patients with lymphoma, chronic lymphocytic leukemia, or solid tumors with liver dysfunction. Romidepsin may stop the growth of cancer...

Active, not recruiting
Recurrent Malignant Solid Neoplasm
Stage IV Prostate Cancer AJCC v7
Other: Pharmacological Study
Drug: Romidepsin

Phase 1

National Cancer Institute (NCI)
National Cancer Institute (NCI)

Cleveland, Ohio, United States and 11 other locations

targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors...

Enrolling
Epithelial Ovarian Cancer
Pancreas Cancer
Drug: BCA101
Drug: Pembrolizumab

Phase 1

Bicara Therapeutics
Bicara Therapeutics

Cleveland, Ohio, United States and 18 other locations

to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...

Enrolling
Advanced Solid Tumor
Non-small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Cleveland, Ohio, United States and 23 other locations

The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and exploratory dose response of paltusotine treatment in subjects with c...

Active, not recruiting
Carcinoid Tumor of Liver
Carcinoid Intestine Tumor
Drug: Randomized: 80 mg Paltusotine
Drug: Randomized: 40 mg Paltusotine

Phase 2

Crinetics Pharmaceuticals

Cleveland, Ohio, United States and 34 other locations

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