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Find clinical trials for Pancreatic Cancer in Cleveland, OH

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Pancreatic Cancer trials near Cleveland, OH, USA:

A Study of Narmafotinib Given in Combination With Modified FOLFIRINOX in Patients With Metastatic Pancreatic Cancer

drugs in a regimen called FOLFIRINOX, to patients who have pancreatic cancer which has metastasised (spread). The study is being ru...

Enrolling
Pancreatic Cancer Metastatic
Drug: narmafotinib dose comparison
Drug: narmafotinib ascending doses

Phase 1, Phase 2

Amplia Therapeutics

Cleveland, Ohio, United States and 5 other locations

Locations recently updated

of borderline-resectable, locally-advanced , or medically inoperable pancreatic adenocarcinoma will translate into a decreased toxicity. The...

Enrolling
Pancreatic Cancer
Radiation: Daily Adaptive External Beam Radiation Therapy
Varian

Cleveland, Ohio, United States and 2 other locations

This phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread...

Enrolling
Metastatic Pancreatic Carcinoma
Stage IV Pancreatic Cancer AJCC v8
Drug: Pemigatinib
Procedure: Bone Scan

Phase 2

Sameek Roychowdhury

Cleveland, Ohio, United States and 108 other locations

phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...

Enrolling
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: AMG 193
Drug: Gemcitabine

Phase 1

Amgen
Amgen

Cleveland, Ohio, United States and 76 other locations

This study is open to adults with advanced pancreatic cancer. The study tests a type of immunotherapy. It is a protein treatment co...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
Drug: ATP150
Drug: ATP152

Phase 1

Boehringer Ingelheim
Boehringer Ingelheim

Cleveland, Ohio, United States and 24 other locations

(PK) and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in participants with advanced solid tumors...

Enrolling
Advanced Solid Tumor
Drug: Olaparib
Drug: XL309

Phase 1

Exelixis
Exelixis

Cleveland, Ohio, United States and 15 other locations

advanced cancers having a specific KRAS mutation will be included.In Part B (Phase 2), participants will be assigned to receive one of up t...

Enrolling
Advanced Solid Cancer
KRAS G12D Mutation
Drug: ARV-806

Phase 1, Phase 2

Arvinas
Arvinas

Cleveland, Ohio, United States and 13 other locations

The goal of this clinical trial is to learn if an investigational drug CP-383 works to treat advanced cancer. It will also learn about the s...

Enrolling
Small Cell Lung Cancer ( SCLC )
Bladder Cancer
Drug: CP-383

Phase 1, Phase 2

Tasca Therapeutics

Cleveland, Ohio, United States and 12 other locations

to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...

Active, not recruiting
Advanced Solid Tumor
Non-small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Cleveland, Ohio, United States and 57 other locations

The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Cleveland, Ohio, United States and 124 other locations

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