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Find clinical trials for Pancreatic Cancer in Cleveland, OH

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Adenocarcinoma
Cancer
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Non-Small-Cell Lung Carcinoma
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Cleveland, OH, USA:

Locations recently updated

A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion

phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...

Enrolling
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: Cisplatin
Drug: Modified FOLFIRINOX

Phase 1

Amgen
Amgen

Cleveland, Ohio, United States and 1 other location

This is a Phase 1b/2, open-label, multi-center, competitive enrollment and dose-escalation study of HCW9218 in patients with advanced/metastatic pancreatic...

Active, not recruiting
Advanced Pancreatic Carcinoma
Drug: HCW9218

Phase 1, Phase 2

HCW Biologics

Cleveland, Ohio, United States and 4 other locations

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...

Active, not recruiting
Esophageal Cancer
Urologic Cancer
Drug: Niraparib

Phase 2

Tempus AI

Cleveland, Ohio, United States and 79 other locations

nivolumab or standard of care. It is being tested against advanced and/or metastatic solid tumors including gastric, gastroesophageal junction, pancreatic...

Enrolling
Advanced Cancer
Gastric Cancer
Drug: Albumin-Bound Paclitaxel
Drug: Gemcitabine

Phase 1, Phase 2

Transcenta

Cleveland, Ohio, United States and 18 other locations

This is a Phase 1, open-label, 2-part, multi-center study evaluating the safety, tolerability, PK, pharmacodynamics (PD), immunogenicity, and antitum...

Enrolling
Gastric Cancer
Ovarian Cancer
Drug: CUE-102

Phase 1

Cue Biopharma

Cleveland, Ohio, United States and 14 other locations

tumors with liver dysfunction. Romidepsin may stop the growth of cancer cells by entering the cancer cells and by blocking the acti...

Active, not recruiting
Stage IV Prostate Cancer AJCC v7
Stage III Renal Cell Cancer AJCC v7
Drug: Romidepsin
Other: Pharmacological Study

Phase 1

National Cancer Institute (NCI)
National Cancer Institute (NCI)

Cleveland, Ohio, United States and 11 other locations

This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...

Enrolling
Metastatic Cancer
Advanced Cancer
Drug: MRTX849
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Cleveland, Ohio, United States and 97 other locations

This is a Phase 1, open-label, multicenter, dose-escalation and expansion study evaluating the safety, tolerability, PK, pharmacodynamics, and clinic...

Enrolling
Endometrial Cancer
Epithelial Ovarian Cancer
Drug: Nivolumab
Drug: XB002

Phase 1

Exelixis
Exelixis

Cleveland, Ohio, United States and 91 other locations

220 adult participants with hepatocellular carcinoma (HCC), pancreatic ductal adenocarcinoma (PDAC), biliary tract cancers (BTC), e...

Enrolling
Pancreatic Ductal Adenocarcinoma
Triple Negative Breast Cancer
Drug: ABBV-400

Phase 1

AbbVie
AbbVie

Cleveland, Ohio, United States and 26 other locations

This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder. This is a study for people for whom prev...

Enrolling
Bladder Cancer
Biliary Tract Cancer
Drug: brigimadlin

Phase 2

Boehringer Ingelheim
Boehringer Ingelheim

Cleveland, Ohio, United States and 62 other locations

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