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phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...
Phase 1
Cleveland, Ohio, United States and 65 other locations
This is a Phase 1b/2, open-label, multi-center, competitive enrollment and dose-escalation study of HCW9218 in patients with advanced/metastatic pancreatic...
Phase 1, Phase 2
Cleveland, Ohio, United States and 4 other locations
This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder. This is a study for people for ...
Phase 2
Cleveland, Ohio, United States and 48 other locations
as PK and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in subjects with advanced solid tumors...
Phase 1
Cleveland, Ohio, United States and 15 other locations
and antitumor activity of CUE-102 intravenous (IV) monotherapy in HLA-A\*0201 positive patients with WT1 positive recurrent/metastatic solid tumors...
Phase 1
Cleveland, Ohio, United States and 14 other locations
targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors...
Phase 1
Cleveland, Ohio, United States and 18 other locations
to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...
Phase 1
Cleveland, Ohio, United States and 44 other locations
The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and exploratory dose response of paltusotine treatment in subjects with c...
Phase 2
Cleveland, Ohio, United States and 34 other locations
The goal of this clinical trial is to test an experimental treatment (immunotherapy) in pancreatic cancer patients. The main resear...
Phase 1
Cleveland, Ohio, United States and 14 other locations
include tumors in the colon or rectum, the uterus and the cervix (lower part of the uterus), the bladder, and the biliary tract (includes g...
Phase 2
Cleveland, Ohio, United States and 50 other locations
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