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This is a single arm study evaluating the tolerability and markers of pancreatic cancer with a specially designed medical food rest...
Raleigh, North Carolina, United States and 11 other locations
This phase I study is designed to establish the safety, maximally tolerated dose (MTD) and recommended phase II dose (RP2D) of the ERK inhibitor ulix...
Phase 1
Chapel Hill, North Carolina, United States
This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted eff...
Phase 2
Chapel Hill, North Carolina, United States and 60 other locations
immune system to attack the tumor.ASP2138 is a potential new treatment for people with stomach cancer, gastroesophageal junction cancer...
Phase 1
Durham, North Carolina, United States and 21 other locations
given to participants. Part C will use the information from Parts A and B to see if SGN-BB228 is safe and if it works to treat solid tumor cancers...
Phase 1
Durham, North Carolina, United States and 17 other locations
assess a potential correlation between tumor infiltrating lymphocytes (TILs) and clinical benefits in participants with CPI-naïve R/R ovarian cancer...
Phase 1, Phase 2
Durham, North Carolina, United States and 7 other locations
and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers...
Phase 2
Durham, North Carolina, United States and 65 other locations
Subjects with selected solid tumors including non-small cell lung cancer (NSCLC) who have a tumor lesion which is accessible for injection w...
Phase 1
Durham, North Carolina, United States and 1 other location
This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor...
Phase 2
Durham, North Carolina, United States and 122 other locations
This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb23104, to describe safety and tolerability, t...
Phase 1
Durham, North Carolina, United States and 17 other locations
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