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Find clinical trials for Pancreatic Cancer in Durham, NC

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Durham, NC, USA:

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

This phase I study is designed to establish the safety, maximally tolerated dose (MTD) and recommended phase II dose (RP2D) of the ERK inhibitor ulix...

Enrolling
Tumor, Solid
Pancreatic Cancer
Drug: Palbociclib
Drug: Ulixertinib

Phase 1

UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, United States of America

This is a single arm study evaluating the tolerability and markers of pancreatic cancer with a specially designed medical food rest...

Enrolling
Metastatic Pancreatic Adenocarcinoma
Locally Advanced Unresectable Pancreatic Adenocarcinoma
Other: NEAAR Medical Food
Faeth Therapeutics

Raleigh, North Carolina, United States and 11 other locations

to participants. Part C will use the information from Parts A and B to see if PF-08046049/SGN-BB228 is safe and if it works to treat solid tumor...

Enrolling
Non-small Cell Lung Cancer
Colorectal Neoplasms
Drug: PF-08046049

Phase 1

Seagen
Seagen

Durham, North Carolina, United States and 21 other locations

stomach cancer, gastroesophageal junction cancer, (GEJ cancer) or pancreatic cancer. GEJ is where the t...

Enrolling
Pancreatic Adenocarcinoma
Gastroesophageal Junction (GEJ) Adenocarcinoma
Drug: ASP2138
Drug: Irinotecan

Phase 1

Astellas
Astellas

Durham, North Carolina, United States and 36 other locations

This trial will study tisotumab vedotin to find out whether it is an effective treatment alone or with other anticancer drugs for certain solid tumors...

Enrolling
Exocrine Pancreatic Cancer
Colorectal Neoplasms
Drug: cisplatin
Drug: carboplatin

Phase 2

Seagen
Seagen

Durham, North Carolina, United States and 71 other locations

is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236
Drug: RMC-9805

Phase 1

Revolution Medicines
Revolution Medicines

Durham, North Carolina, United States and 16 other locations

and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers...

Active, not recruiting
Neoplasm of Lung
Neoplasms Pancreatic
Drug: Gemcitabine - 21 day cycle
Drug: 9-ING-41

Phase 2

Actuate Therapeutics

Durham, North Carolina, United States and 65 other locations

in participants with checkpoint inhibitor (CPI) treated and naïve relapsed and refractory (R/R) tumors.The main purpose of the Biomarker Co...

Active, not recruiting
Any Advanced Solid Tumors
Small Cell Lung Cancer
Drug: NT-I7
Drug: pembrolizumab (KEYTRUDA®)

Phase 1, Phase 2

NeoImmuneTech

Durham, North Carolina, United States and 7 other locations

This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors th...

Active, not recruiting
Breast Cancer
Neuroendocrine Tumors
Drug: Entrectinib

Phase 2

Roche
Roche

Durham, North Carolina, United States and 122 other locations

and recommended phase II dose (RP2D). Subjects with selected solid tumors including non-small cell lung cancer (NSCLC) who have a t...

Enrolling
Metastatic Cancer
Advanced Cancer
Biological: Nivolumab
Biological: MEM-288 Intratumoral Injection

Phase 1

Memgen

Durham, North Carolina, United States and 1 other location

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