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A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for advanced pancreatic cancer...
Montréal, Quebec, Canada and 1 other location
Salmonella Typhimurium expressing IL-2, in patients with metastatic pancreatic cancer on standard chemotherapy (either FOLFIRINOX o ...
Phase 2
Montreal, Quebec, Canada
with either gemcitabine plus nab-paclitaxel (G/NP) or FOLFIRINOX in the treatment of participants with locally advanced, unresectable pancreatic...
Phase 3
Montreal, Quebec, Canada and 89 other locations
of AZD0901 as monotherapy and in combination with anti-cancer agents in participants with locally advanced unresectable or metastatic solid ...
Phase 2
Montreal, Quebec, Canada and 46 other locations
given to participants. Part C will use the information from Parts A and B to see if SGN-BB228 is safe and if it works to treat solid tumor cancers...
Phase 1
Montreal, Quebec, Canada and 17 other locations
This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer age...
Phase 1, Phase 2
Montreal, Quebec, Canada and 71 other locations
and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers...
Phase 2
Montréal, Quebec, Canada and 65 other locations
The primary purpose of this study is to find the recommended dose of LGK974 as a single agent and in combination with PDR001 that can be safely given...
Phase 1
Montreal, Quebec, Canada and 19 other locations
BOLD-100 is an intravenously administered sterile solution containing the ruthenium-based small molecule. BOLD-100 has been shown to preferentially d...
Phase 1, Phase 2
Montréal, Quebec, Canada and 12 other locations
This is an open-label, multi-center, phase 1b study designed to determine a tolerable dose of CX-5461 administered by IV infusion on Day 1 and Day 8...
Phase 1
Montréal, Quebec, Canada and 7 other locations
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