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This is a multi-center clinical study enrolling up to 30 participants (15 patients in each cohort). The primary objective of the study is to evaluate...
Orlando, Florida, United States and 15 other locations
receiving lower radiation doses, in patients with locally advanced pancreatic cancer, without increasing the rate of serious gastro...
Orlando, Florida, United States and 12 other locations
ONIVYDE + LV + 5-FU chemotherapy regimen in patients with advanced pancreatic cancer and to determine the recommended dose for the ...
Phase 1, Phase 2
Lake Mary, Florida, United States and 27 other locations
(PK) and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in participants with advanced solid tumors...
Phase 1
Orlando, Florida, United States and 15 other locations
A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS or EGFR mutations to determine the maximum tolerated d...
Phase 1
Orlando, Florida, United States and 11 other locations
The goal of this clinical trial is to evaluate FMC-376 in participants with advanced solid tumors with KRAS G12C mutations. This clinical tr...
Phase 1, Phase 2
Lake Mary, Florida, United States and 20 other locations
activity of MOMA-313 administered orally as a single agent or combination therapy in patients with homologous recombinant deficient solid tumors...
Phase 1
Lake Mary, Florida, United States and 14 other locations
effective in participants with select advanced or metastatic solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, ...
Phase 1
Orlando, Florida, United States and 27 other locations
This is a Phase 1, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with adv...
Phase 1
Orlando, Florida, United States and 23 other locations
This is a Phase 1, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with adv...
Phase 1
Orlando, Florida, United States and 23 other locations
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