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This phase I trial studies the sides effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic...
Phase 1
Salt Lake City, Utah, United States and 1 other location
A phase IIb, open-label, randomized study of Nab-Paclitaxel and Gemcitabine and plus/minus VCN-01 in Patients with Metastatic Pancreatic Cancer...
Phase 2
Salt Lake City, Utah, United States and 16 other locations
ONIVYDE + LV + 5-FU chemotherapy regimen in patients with advanced pancreatic cancer and to determine the recommended dose for the ...
Phase 1, Phase 2
Ogden, Utah, United States of America and 27 other locations
in combination with gemcitabine and nab-paclitaxel in patients with Pancreatic Ductal Adenocarcinoma (PDAC) who have been previously untreat...
Phase 1, Phase 2
Salt Lake City, Utah, United States and 10 other locations
The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall surviv...
Phase 2
Salt Lake City, Utah, United States and 137 other locations
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Phase 1
Salt Lake City, Utah, United States and 14 other locations
and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers...
Phase 2
Salt Lake City, Utah, United States and 65 other locations
The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...
Phase 2
Salt Lake City, Utah, United States and 79 other locations
This is a Phase I/II, open-label, multi-center, multi-national, dose escalation, single agent study to assess the safety, tolerability, PK, PD, immun...
Phase 2
Salt Lake City, Utah, United States and 64 other locations
This is a Phase 1, First-in-Human (FIH), open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, phar...
Phase 1
Salt Lake City, Utah, United States and 5 other locations
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