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trial investigating the use of short term androgen deprivation therapy in the form of apalutamide (Erleada) in men on active surveillance for prostate...
Phase 3
Cambridge, Cambridgeshire, United Kingdom
A first-in-human clinical trial to test the investigational treatment ONCT-534 in participants with metastatic castration-resistant prostate ...
Phase 1, Phase 2
Sutton, Surrey, United Kingdom and 7 other locations
androgen deprivation therapy (ADT) with a luteinising hormone releasing hormone analogue (LHRHA) in men having radiation therapy for localised prostate...
Phase 3
London, United Kingdom and 92 other locations
The purpose of this trial is to investigate the safety and tolerability of TAS3681, to find the maximum tolerated dose (MTD)/recommended dose of TAS3...
Phase 1
London, England, United Kingdom and 33 other locations
This is a Phase 1/2, open-label, randomized, dose finding and dose expansion study to evaluate the safety, preliminary efficacy, and PK of gedatolisi...
Phase 1, Phase 2
Sutton, United Kingdom and 12 other locations
The purpose of this study is to investigate potential drug-drug interaction (DDI) between JNJ-56021927 and abiraterone acetate and between JNJ-560219...
Phase 1
Sutton, United Kingdom and 6 other locations
Effects of Saruparib (AZD5305) Alone, Darolutamide Alone, and in Combination Given Prior to Radical Prostatectomy in Men with Newly Diagnosed Prostate...
Phase 1
Cambridge, United Kingdom and 16 other locations
Phase 1b study to assess the combination of ARV-110 and abiraterone in patients with metastatic prostate cancer with rising PSA val...
Phase 1
London, England, United Kingdom and 17 other locations
The study will be conducted in 4 parts and will commence with dose escalation of AMX-500 as a monotherapy (Part 1), followed by monotherapy dose expa...
Phase 1, Phase 2
London, United Kingdom and 7 other locations
and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemo ...
Phase 3
Guildford, United Kingdom and 131 other locations
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