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Find clinical trials for Prostate Cancer in Philadelphia, PA

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Related conditions:

Prostatic Cancer
Cancer
Carcinoma
Hypersensitivity
Adenocarcinoma
Recurrence
Castration-Resistant Prostatic Cancer

Prostate Cancer trials near Philadelphia, PA, USA:

Study of AZD0754 in Participants With Metastatic Prostate Cancer (APOLLO)

of this study is to evaluate the safety, tolerability, and antitumour activity of AZD0754 CAR T-cell therapy in participants with metastatic prostate...

Enrolling
Metastatic Prostate Cancer
Biological: AZD0754

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Philadelphia, Pennsylvania, United States and 8 other locations

A Phase 1/2a, open-label, multicenter study of intramuscular (i.m.) PRL-02 depot in participants with advanced prostate cancer....

Enrolling
Prostate Cancer
mCSPC
Drug: docetaxel infusion
Drug: PRL-02 injection

Phase 1, Phase 2

Astellas
Astellas

Bala-Cynwyd, Pennsylvania, United States and 13 other locations

This was a randomized study to evaluate the risk of major adverse cardiovascular events (MACE) for relugolix compared with leuprolide acetate. Enroll...

Active, not recruiting
Prostate Cancer
Drug: Leuprolide Acetate
Drug: Relugolix

Phase 3

Sumitomo Pharma
Sumitomo Pharma

Bala-Cynwyd, Pennsylvania, United States and 107 other locations

This study seeks to determine the clinical impact of Gene Expression Classifier (GEC) testing in prostate cancer care while also de...

Enrolling
Prostate Cancer
Device: Oncotype Dx Genomic Prostate Score (GPS)
Device: Prolaris
University of Michigan Rogel Cancer Center
University of Michigan Rogel Cancer Center

Philadelphia, Pennsylvania, United States and 6 other locations

A Phase 1/2 study to evaluate the safety and efficacy of ARV-766 given by mouth alone or in combination with abiraterone in men with metastatic prostate...

Enrolling
Prostate Cancer Metastatic
Drug: ARV-766 + Abiraterone Part C&D
Drug: ARV-766 Part A&B

Phase 1, Phase 2

Arvinas
Arvinas

Philadelphia, Pennsylvania, United States and 22 other locations

inhibitor, in Veterans with metastatic castration-resistant prostate cancer (mCRPC) characterized by either mismatch repair deficie...

Enrolling
Metastatic Castration Resistant Prostate Cancer
Drug: Pembrolizumab

Phase 2

VA Office of Research and Development
VA Office of Research and Development

Philadelphia, Pennsylvania, United States and 11 other locations

and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemo ...

Active, not recruiting
Metastatic Castration-resistant Prostate Cancer
Drug: abiraterone acetate
Drug: olaparib

Phase 3

AstraZeneca
AstraZeneca

Philadelphia, Pennsylvania, United States and 131 other locations

Evaluate the safety and tolerability of AMG 509 in adult participants and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2...

Enrolling
Prostate Cancer
Drug: Abiraterone
Drug: Enzalutamide

Phase 1

Amgen
Amgen

Philadelphia, Pennsylvania, United States and 48 other locations

radiation therapy for patients with intermediate-high risk localized prostate cancer. ProstAtak kills tumor cells and stimulates a ...

Active, not recruiting
Prostate Cancer
Biological: Placebo + valacyclovir
Biological: Aglatimagene besadenovec + valacyclovir

Phase 3

Candel Therapeutics

Bala-Cynwyd, Pennsylvania, United States and 72 other locations

of vudalimab (XmAb20717) alone or in combination with standard of care anticancer therapies in patients with metastatic castration-resistant prostate...

Enrolling
Metastatic Castration-Resistant Prostate Cancer
Biological: vudalimab monotherapy
Combination Product: vudalimab + olaparib

Phase 2

Xencor
Xencor

Philadelphia, Pennsylvania, United States and 16 other locations

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