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Find clinical trials for Triple Negative Breast Cancer in Charlotte, NC

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Related conditions:

Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
Endometrial Cancer
Squamous Cell Carcinoma

Triple Negative Breast Cancer trials near Charlotte, NC, USA:

Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer (ToPCourT)

and carboplatin in locally advanced unresectable or metastatic triple-negative breast cancer.The main questions i...

Enrolling
Metastatic Triple-Negative Breast Cancer
Drug: Gemcitabine
Drug: Pembrolizumab

Phase 2

Wake Forest University (WFU)
Wake Forest University (WFU)

Charlotte, North Carolina, United States

doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC). Usually, after neoadjuvant therapy and surgery for triple ne ...

Active, not recruiting
Triple Negative Breast Cancer
Drug: Placebo
Drug: Atezolizumab

Phase 3

National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP)

Charlotte, North Carolina, United States and 216 other locations

previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors do no...

Enrolling
Triple Negative Breast Cancer
PD-L1 Negative
Drug: Sacituzumab Govitecan-hziy
Drug: Paclitaxel

Phase 3

Gilead Sciences
Gilead Sciences

Charlotte, North Carolina, United States and 508 other locations

This is a Phase III, randomised, open-label, 2 arm, multicentre, international study assessing the efficacy and safety of Dato-DXd compared with ICC...

Active, not recruiting
Breast Cancer
Drug: Paclitaxel
Drug: Eribulin mesylate

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 228 other locations

for patients with previously untreated, locally advanced, unresectable or metastatic (Stage IV) programmed death-ligand 1 (PD-L1)-positive triple...

Enrolling
Breast Cancer
Drug: Tobemstomig
Drug: Nab-Paclitaxel

Phase 2

Roche
Roche

Charlotte, North Carolina, United States and 100 other locations

with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...

Enrolling
Breast Cancer
Drug: Pembrolizumab
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 359 other locations

(with enzalutamide-naïve metastatic castration-resistant prostate cancer) will be randomized to receive either NUV-868 monotherapy, enzaluta...

Enrolling
Triple Negative Breast Neoplasms
Cancer of Ovary
Drug: Enzalutamide
Drug: NUV-868

Phase 1, Phase 2

Nuvation Bio

Huntersville, North Carolina, United States of America and 31 other locations

A study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) an...

Active, not recruiting
Non-small-cell-lung-cancer (NSCLC)
Cancer
Drug: ABBV-368
Drug: ABBV-927

Phase 1

AbbVie
AbbVie

Huntersville, North Carolina, United States of America and 25 other locations

This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced...

Enrolling
Ovarian Cancer
Triple Negative Breast Cancer
Drug: APL-5125

Phase 1, Phase 2

Apollo Therapeutics

Huntersville, North Carolina, United States and 2 other locations

to evaluate safety and efficacy of an antibody drug conjugate U3-1402 (patritumab deruxtecan) in patients with locally advanced or metastatic breast...

Enrolling
Locally Advanced Breast Cancer
Metastatic Breast Cancer
Drug: U3-1402

Phase 2

SCRI Development Innovations

Charlotte, North Carolina, United States and 10 other locations

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