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and carboplatin in locally advanced unresectable or metastatic triple-negative breast cancer.The main questions i...
Phase 2
Charlotte, North Carolina, United States
doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC). Usually, after neoadjuvant therapy and surgery for triple ne ...
Phase 3
Charlotte, North Carolina, United States and 216 other locations
for patients with previously untreated, locally advanced, unresectable or metastatic (Stage IV) programmed death-ligand 1 (PD-L1)-positive triple...
Phase 2
Charlotte, North Carolina, United States and 60 other locations
This is a Phase III, randomised, open-label, 2 arm, multicentre, international study assessing the efficacy and safety of Dato-DXd compared with ICC...
Phase 3
Charlotte, North Carolina, United States and 225 other locations
previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors...
Phase 3
Charlotte, North Carolina, United States and 516 other locations
with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...
Phase 3
Charlotte, North Carolina, United States and 275 other locations
(ABBV-181) and/or chemotherapy in participants with selected solid tumors. This study consists of 2 main parts, a dose-escalation phase and ...
Phase 1
Huntersville, North Carolina, United States of America and 25 other locations
1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors...
Phase 1, Phase 2
Huntersville, North Carolina, United States of America and 8 other locations
to evaluate safety and efficacy of an antibody drug conjugate U3-1402 (patritumab deruxtecan) in patients with locally advanced or metastatic breast...
Phase 2
Charlotte, North Carolina, United States and 10 other locations
with standard of care treatment (docetaxel) or another antibody cancer drug, pembrolizumab (with or without chemotherapy), for treatment of ...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 56 other locations
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