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Find clinical trials for Triple Negative Breast Cancer in Cleveland, OH

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Related conditions:

Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Non-Small-Cell Lung Carcinoma
Ovarian Cancer

Triple Negative Breast Cancer trials near Cleveland, OH, USA:

Establishing the Recommended Biological Dose for AE37 Peptide Vaccine in Combination With Pembrolizumab That Will Enhance the Tumor-specific Immune Response and Demonstrate Efficacy in Patients With Advanced Triple-negative Breast Cancer (NSABP FB-14)

This study will look to establish the recommended biologic dose of AE37 in combination with pembrolizumab that will enhance the tumor-specif-...

Active, not recruiting
Triple-negative Breast Cancer
Biological: Pembrolizumab
Biological: AE37 Peptide vaccine

Phase 2

NuGenerex Immuno-Oncology

Cleveland, Ohio, United States and 5 other locations

This is a Phase 2, Multi-Cohort, Open-Label, Multi-Center Study. Cohort 1 will be a single-arm study of intratumoral tavokinogene telseplasmid (TAVO)...

Active, not recruiting
Triple Negative Breast Cancer
Device: Immunopulse
Drug: nab paclitaxel

Phase 2

OncoSec Medical

Cleveland, Ohio, United States and 13 other locations

with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...

Enrolling
Breast Cancer
Drug: Pembrolizumab
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 360 other locations

This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without du...

Enrolling
Breast Cancer
Drug: Paclitaxel
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 286 other locations

(HCC), pancreatic ductal adenocarcinoma (PDAC), biliary tract cancers (BTC), esophageal squamous cell carcinoma (ESCC), triple negative...

Enrolling
Triple Negative Breast Cancer
Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer
Drug: ABBV-400

Phase 1

AbbVie
AbbVie

Cleveland, Ohio, United States and 39 other locations

This study will test the safety of a drug called PF-08046054/SGN-PDL1V alone and with pembrolizumab in participants with solid tumors. It wi ...

Enrolling
Ovarian Neoplasms
Gastric Cancer
Drug: pembrolizumab
Drug: PF-08046054

Phase 1

Seagen
Seagen

Cleveland, Ohio, United States and 23 other locations

The primary purpose of this study is to assess the safety and tolerability of AB598 when taken alone, and in combination with zimberelimab and standa...

Enrolling
Triple Negative Breast Cancer (TNBC)
Esophageal Cancer
Drug: AB598
Drug: Oxaliplatin

Phase 1

Arcus Biosciences
Arcus Biosciences

Cleveland, Ohio, United States and 9 other locations

tumors....

Enrolling
Endometrial Cancer
Triple Negative Breast Cancer
Biological: NM32-2668

Phase 1

Numab Therapeutics

Cleveland, Ohio, United States and 5 other locations

study will assess the safety and tolerability of escalating intratumoral doses of mRNA-2752 in participants with relapsed/refractory solid tumor...

Active, not recruiting
Dose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma
Biological: mRNA-2752
Biological: Durvalumab

Phase 1

Moderna
Moderna

Cleveland, Ohio, United States and 23 other locations

is to evaluate the safety of acasunlimab (also known as GEN1046) as monotherapy and in combination therapies in patients with malignant solid tumors...

Active, not recruiting
Non-small Cell Lung Cancer
Triple Negative Breast Cancer
Biological: Acasunlimab in combination with pembrolizumab (in a separate expansion cohort)
Biological: Acasunlimab in combination with docetaxel (in a single expansion cohort)

Phase 1, Phase 2

Genmab
Genmab

Cleveland, Ohio, United States and 56 other locations

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