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immune response and demonstrate efficacy in patients with advanced triple-negative breast cancer.This study will ...
Phase 2
Cleveland, Ohio, United States and 5 other locations
This is a Phase 2, Multi-Cohort, Open-Label, Multi-Center Study. Cohort 1 will be a single-arm study of intratumoral tavokinogene telseplasmid (TAVO)...
Phase 2
Cleveland, Ohio, United States and 13 other locations
with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...
Phase 3
Cleveland, Ohio, United States and 275 other locations
This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without du...
Phase 3
Cleveland, Ohio, United States and 317 other locations
This study, the first clinical trial of AVZO-021, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated d...
Phase 1, Phase 2
Cleveland, Ohio, United States and 12 other locations
Phase 1/2, Open-label, Multi-center, First-in-human Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of...
Phase 1, Phase 2
Cleveland, Ohio, United States and 6 other locations
of NKT5097 in adults with advanced/metastatic tumors (emphasis on breast cancer and solid tumors with CCNE1 amplification). Main qu...
Phase 1
Cleveland, Ohio, United States and 17 other locations
carcinoma (ESCC), triple negative breast cancer (TNBC), hormone receptor+/human epidermal growth factor receptor ...
Phase 1
Cleveland, Ohio, United States and 54 other locations
to treatment of physician's choice (TPC) in participants with triple-negative breast cancer (TNBC) who received n...
Phase 3
Massillon, Ohio, United States and 309 other locations
with advanced, or metastatic solid tumors including urothelial cancer. The study is conducted in two parts - phase Ia (dose-escalation, dose...
Phase 1
Cleveland, Ohio, United States and 38 other locations
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