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Find clinical trials for Triple Negative Breast Cancer in Cleveland, OH

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Related conditions:

Breast Cancer
Non-Small-Cell Lung Carcinoma
Cancer
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Ovarian Cancer
Carcinoma

Triple Negative Breast Cancer trials near Cleveland, OH, USA:

Establishing the Recommended Biological Dose for AE37 Peptide Vaccine in Combination With Pembrolizumab That Will Enhance the Tumor-specific Immune Response and Demonstrate Efficacy in Patients With Advanced Triple-negative Breast Cancer (NSABP FB-14)

This study will look to establish the recommended biologic dose of AE37 in combination with pembrolizumab that will enhance the tumor-specif-...

Active, not recruiting
Triple-negative Breast Cancer
Biological: Pembrolizumab
Biological: AE37 Peptide vaccine

Phase 2

NuGenerex Immuno-Oncology

Cleveland, Ohio, United States and 5 other locations

This is a Phase 2, Multi-Cohort, Open-Label, Multi-Center Study. Cohort 1 will be a single-arm study of intratumoral tavokinogene telseplasmid (TAVO)...

Active, not recruiting
Triple Negative Breast Cancer
Device: Immunopulse
Drug: nab paclitaxel

Phase 2

OncoSec Medical

Cleveland, Ohio, United States and 13 other locations

pharmacokinetics, pharmacodynamics, maximum tolerated dose, and anti-tumor effects of AVZO-021 in patients with advanced solid tumors...

Enrolling
Endometrial Cancer
Primary Peritoneal Cancer
Drug: Sacituzumab Govitecan-hziy
Drug: Ribociclib

Phase 1, Phase 2

Avenzo Therapeutics

Cleveland, Ohio, United States and 10 other locations

Phase 1/2, Open-label, Multi-center, First-in-human Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Anti-tumor Act...

Enrolling
Advanced Solid Tumor
Biological: STX-001
Biological: Keytruda®

Phase 1, Phase 2

Strand Therapeutics

Cleveland, Ohio, United States and 6 other locations

with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...

Active, not recruiting
Breast Cancer
Drug: Pembrolizumab
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 275 other locations

(ESCC), triple negative breast cancer (TNBC), hormone receptor+/human epidermal growth factor receptor 2 negative...

Enrolling
Platinum Resistant High Grade Epithelial Ovarian Cancer
Triple Negative Breast Cancer
Drug: Itraconazole (ITZ)
Drug: ABBV-400

Phase 1

AbbVie
AbbVie

Cleveland, Ohio, United States and 53 other locations

to treatment of physician's choice (TPC) in participants with triple-negative breast cancer (TNBC) who received n...

Enrolling
Triple-Negative Breast Cancer
Biological: Pembrolizumab
Biological: Sacituzumab tirumotecan

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Massillon, Ohio, United States and 250 other locations

This study will test the safety of a drug called PF-08046054/SGN-PDL1V alone and with pembrolizumab in participants with solid tumors. It wi ...

Enrolling
Ovarian Neoplasms
Gastric Cancer
Drug: pembrolizumab
Drug: PF-08046054

Phase 1

Seagen, a wholly owned subsidiary of Pfizer

Cleveland, Ohio, United States and 55 other locations

This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without du...

Enrolling
Breast Cancer
Drug: Paclitaxel
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 306 other locations

The goal of this clinical trial is to learn if the drug TUB-030 works to treat solid cancer in adults. The study will also explore the safet...

Enrolling
TNBC - Triple-Negative Breast Cancer
Advanced Solid Tumors
Drug: TUB-030

Phase 1, Phase 2

Tubulis

Cleveland, Ohio, United States and 12 other locations

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