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Find clinical trials for Triple Negative Breast Cancer in Indianapolis, IN

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Related conditions:

Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Non-Small-Cell Lung Carcinoma
Squamous Cell Carcinoma

Triple Negative Breast Cancer trials near Indianapolis, IN, USA:

Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer

This randomized phase II trial studies how well carboplatin with or without atezolizumab works in treating patients with stage IV triple negative...

Active, not recruiting
HER2 Negative
Triple Negative Breast Cancer
Other: Quality-of-Life Assessment
Drug: Carboplatin

Phase 2

Vanderbilt University Medical Center
Vanderbilt University Medical Center

Indianapolis, Indiana, United States and 5 other locations

and to evaluate the efficacy of this combination in advanced HER2 negative breast cancer that is triple negative...

Active, not recruiting
TNBC - Triple-Negative Breast Cancer
Drug: Gedatolisib
Drug: Talazoparib

Phase 1, Phase 2

Kari Wisinski

Indianapolis, Indiana, United States and 4 other locations

This is a 3-arm study stratified by plasma ctDNA. Patients with residual TNBC disease after pre-operative therapy will be assigned to 1 of 3 Arms bas...

Enrolling
Breast Cancer
Triple Negative Breast Cancer
Drug: Inavolisib
Drug: Talazoparib

Phase 2

Bryan Schneider, MD

Indianapolis, Indiana, United States and 12 other locations

Phase II study of carboplatin monotherapy vs. carboplatin combined with tocilizumab in in Black and non-Black patients with metastatic triple...

Enrolling
Estrogen-receptor-low Breast Cancer
Metastatic Breast Cancer
Drug: Tocilizumab
Drug: Carboplatin

Phase 2

Kathy Miller

Indianapolis, Indiana, United States and 2 other locations

or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...

Enrolling
Triple Negative Breast Cancer
Drug: Capecitabine
Drug: Sacituzumab govitecan-hziy (SG)

Phase 3

Gilead Sciences
Gilead Sciences

Indianapolis, Indiana, United States and 110 other locations

TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...

Active, not recruiting
Cancer
Drug: pembrolizumab
Drug: TTX-080

Phase 1

Tizona Therapeutics

Indianapolis, Indiana, United States and 39 other locations

does to the body besides treating the disease.Participants will have cancer that has spread in the body near where it started (locally advan...

Enrolling
Hormone Receptor Positive Breast Neoplasms
Triple Negative Breast Neoplasms
Drug: SGN-B7H4V

Phase 1

Seagen
Seagen

Indianapolis, Indiana, United States and 17 other locations

Locations recently updated

The study will determine the recommended Phase 2 dose (RP2D) of livmoniplimab (ABBV-151) administered as monotherapy and in combination with budigali...

Enrolling
Advanced Solid Tumors Cancer
Drug: Livmoniplimab
Drug: Budigalimab

Phase 1

AbbVie
AbbVie

Indianapolis, Indiana, United States and 37 other locations

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers...

Enrolling
Squamous Non-small-cell Lung Cancer
Endometrium Cancer
Drug: VLS-1488

Phase 1, Phase 2

Volastra Therapeutics

Indianapolis, Indiana, United States and 8 other locations

The primary purpose of this study is to determine the antitumor activity of enfortumab vedotin as measured by confirmed objective response rate (ORR)...

Enrolling
Locally Advanced or Metastatic Malignant Solid Tumors
Drug: pembrolizumab
Drug: enfortumab vedotin

Phase 2

Astellas
Astellas

Indianapolis, Indiana, United States and 50 other locations

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