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Find clinical trials for Triple Negative Breast Cancer in Indianapolis, IN

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Related conditions:

Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Non-Small-Cell Lung Carcinoma
Ovarian Epithelial Carcinoma

Triple Negative Breast Cancer trials near Indianapolis, IN, USA:

Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers

and to evaluate the efficacy of this combination in advanced HER2 negative breast cancer that is triple negative...

Active, not recruiting
TNBC - Triple-Negative Breast Cancer
Drug: Talazoparib
Drug: Gedatolisib

Phase 1, Phase 2

Kari Wisinski

Indianapolis, Indiana, United States and 4 other locations

This is a 3-arm study stratified by plasma ctDNA. Patients with residual TNBC disease after pre-operative therapy will be assigned to 1 of 3 Arms bas...

Active, not recruiting
Breast Cancer
Triple Negative Breast Cancer
Drug: Inavolisib
Drug: Talazoparib

Phase 2

Bryan Schneider, MD

Indianapolis, Indiana, United States and 12 other locations

of care (SOC) chemotherapy monotherapy vs. SOC chemotherapy combined with tocilizumab in in Black and non-Black patients with metastatic triple...

Enrolling
Estrogen-receptor-low Breast Cancer
Metastatic Breast Cancer
Drug: Tocilizumab
Drug: SOC Chemotherapy

Phase 2

Kathy Miller

Indianapolis, Indiana, United States and 3 other locations

or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...

Enrolling
Triple Negative Breast Cancer
Drug: Capecitabine
Drug: Sacituzumab govitecan-hziy (SG)

Phase 3

Gilead Sciences
Gilead Sciences

Indianapolis, Indiana, United States of America and 176 other locations

levels in combination with chemotherapeutic agents in the first- and second-line treatment of participants with locally advanced/metastatic triple...

Enrolling
Locally Advanced Breast Cancer
Metastatic Triple Negative Breast Cancers
Drug: BNT327 Equivalent Q3W Dose
Drug: BNT327 Dose Level 1 (DL2)

Phase 2

BioNTech
BioNTech

Indianapolis, Indiana, United States and 63 other locations

cancers.* Part D will find out if and how much SGN-B7H4V can be given with pembrolizumab.* Part E will use the amount found in Part D to fi ...

Active, not recruiting
Ovarian Neoplasms
Hormone Receptor Positive Breast Neoplasms
Drug: SGN-B7H4V
Drug: Pembrolizumab

Phase 1

Seagen
Seagen

Indianapolis, Indiana, United States and 18 other locations

The primary objective of this study is to evaluate the safety, tolerability, MTD and RP2D of LP-184 in patients with advanced solid tumors w...

Enrolling
TNBC - Triple-Negative Breast Cancer
Advanced Solid Tumor
Drug: LP-184
Drug: Spironolactone

Phase 1, Phase 2

Lantern Pharma

Indianapolis, Indiana, United States and 8 other locations

including metastatic colorectal cancer (mCRC) patients....

Enrolling
Cancer
Drug: cetuximab
Drug: FOLFIRI

Phase 1

Tizona Therapeutics

Indianapolis, Indiana, United States and 38 other locations

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers...

Enrolling
Squamous Non-small-cell Lung Cancer
Advanced Solid Tumor
Drug: VLS-1488

Phase 1, Phase 2

Volastra Therapeutics

Indianapolis, Indiana, United States and 11 other locations

Locations recently updated

The study will determine the recommended Phase 2 dose (RP2D) of livmoniplimab (ABBV-151) administered as monotherapy and in combination with budigali...

Enrolling
Advanced Solid Tumors Cancer
Drug: Livmoniplimab
Drug: Budigalimab

Phase 1

AbbVie
AbbVie

Indianapolis, Indiana, United States and 59 other locations

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