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and to evaluate the efficacy of this combination in advanced HER2 negative breast cancer that is triple negative...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 4 other locations
This is a 3-arm study stratified by plasma ctDNA. Patients with residual TNBC disease after pre-operative therapy will be assigned to 1 of 3 Arms bas...
Phase 2
Indianapolis, Indiana, United States and 12 other locations
of care (SOC) chemotherapy monotherapy vs. SOC chemotherapy combined with tocilizumab in in Black and non-Black patients with metastatic triple...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...
Phase 3
Indianapolis, Indiana, United States of America and 176 other locations
levels in combination with chemotherapeutic agents in the first- and second-line treatment of participants with locally advanced/metastatic triple...
Phase 2
Indianapolis, Indiana, United States and 63 other locations
cancers.* Part D will find out if and how much SGN-B7H4V can be given with pembrolizumab.* Part E will use the amount found in Part D to fi ...
Phase 1
Indianapolis, Indiana, United States and 18 other locations
The primary objective of this study is to evaluate the safety, tolerability, MTD and RP2D of LP-184 in patients with advanced solid tumors w...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 8 other locations
including metastatic colorectal cancer (mCRC) patients....
Phase 1
Indianapolis, Indiana, United States and 38 other locations
This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 11 other locations
The study will determine the recommended Phase 2 dose (RP2D) of livmoniplimab (ABBV-151) administered as monotherapy and in combination with budigali...
Phase 1
Indianapolis, Indiana, United States and 59 other locations
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