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Find clinical trials for Triple Negative Breast Cancer in Indianapolis, IN

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Related conditions:

Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Non-Small-Cell Lung Carcinoma
Ovarian Cancer

Triple Negative Breast Cancer trials near Indianapolis, IN, USA:

Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers

and to evaluate the efficacy of this combination in advanced HER2 negative breast cancer that is triple negative...

Active, not recruiting
TNBC - Triple-Negative Breast Cancer
Drug: Talazoparib
Drug: Gedatolisib

Phase 1, Phase 2

Kari Wisinski

Indianapolis, Indiana, United States and 4 other locations

This is a 3-arm study stratified by plasma ctDNA. Patients with residual TNBC disease after pre-operative therapy will be assigned to 1 of 3 Arms bas...

Active, not recruiting
Breast Cancer
Triple Negative Breast Cancer
Drug: Inavolisib
Drug: Talazoparib

Phase 2

Bryan Schneider, MD

Indianapolis, Indiana, United States and 12 other locations

Phase II study of carboplatin monotherapy vs. carboplatin combined with tocilizumab in in Black and non-Black patients with metastatic triple...

Enrolling
Estrogen-receptor-low Breast Cancer
Metastatic Breast Cancer
Drug: Tocilizumab
Drug: Carboplatin

Phase 2

Kathy Miller

Indianapolis, Indiana, United States and 3 other locations

or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...

Enrolling
Triple Negative Breast Cancer
Drug: Capecitabine
Drug: Sacituzumab govitecan-hziy (SG)

Phase 3

Gilead Sciences
Gilead Sciences

Indianapolis, Indiana, United States of America and 166 other locations

cancers.* Part D will find out if and how much SGN-B7H4V can be given with pembrolizumab.* Part E will use the amount found in Part D to fi ...

Enrolling
Ovarian Neoplasms
Hormone Receptor Positive Breast Neoplasms
Drug: SGN-B7H4V
Drug: Pembrolizumab

Phase 1

Seagen
Seagen

Indianapolis, Indiana, United States and 18 other locations

including metastatic colorectal cancer (mCRC) patients....

Enrolling
Cancer
Drug: cetuximab
Drug: FOLFIRI

Phase 1

Tizona Therapeutics

Indianapolis, Indiana, United States and 38 other locations

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers...

Enrolling
Squamous Non-small-cell Lung Cancer
Advanced Solid Tumor
Drug: VLS-1488

Phase 1, Phase 2

Volastra Therapeutics

Indianapolis, Indiana, United States and 10 other locations

Locations recently updated

The study will determine the recommended Phase 2 dose (RP2D) of livmoniplimab (ABBV-151) administered as monotherapy and in combination with budigali...

Enrolling
Advanced Solid Tumors Cancer
Drug: Livmoniplimab
Drug: Budigalimab

Phase 1

AbbVie
AbbVie

Indianapolis, Indiana, United States and 53 other locations

The primary purpose of this study is to determine the antitumor activity of enfortumab vedotin as measured by confirmed objective response rate (ORR)...

Active, not recruiting
Locally Advanced or Metastatic Malignant Solid Tumors
Drug: pembrolizumab
Drug: enfortumab vedotin

Phase 2

Astellas
Astellas

Indianapolis, Indiana, United States and 38 other locations

The primary objectives of this study are to observe the safety and tolerability of bemarituzumab and to evaluate preliminary antitumor activity.

Enrolling
Solid Tumors
Drug: Bemarituzumab

Phase 1, Phase 2

Amgen
Amgen

Indianapolis, Indiana, United States and 114 other locations

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