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Atrium Health Wake Forest Baptist | Anesthesiology Department

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Bitopertin
Alendronate
Pembrolizumab
Sacituzumab
Vancomycin
DISC-1459
Fianlimab
Histidine
IDP-023
ISIS 702843

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Active trials

13 of 60 total trials

A Study to Evaluate Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx) in Patients With Polycythemia Vera

The main purpose of this study is to evaluate the efficacy of sapablursen in reducing the frequency of phlebotomy and in improving quality of life as...

Enrolling
Phlebotomy Dependent Polycythemia Vera
Drug: sapablursen

This study is researching an experimental drug called linvoseltamab in combination with other drugs for the treatment of a blood cancer called multip...

Enrolling
Multiple Myeloma
Drug: Bortezomib
Drug: Nirogacestat

To evaluate the safety and efficacy of intravenous (IV) administration of bone marrow mesenchymal stem cell derived extracellular vesicles (EVs), Exo...

Enrolling
Acute Respiratory Distress Syndrome
ARDS
Other: Intravenous normal saline
Biological: ExoFlo

The goal of this clinical trial is to test the feasibility of a web app about colorectal cancer screening in patients with an upcoming primary care a...

Not yet enrolling
Colorectal Cancer Screening
Other: mPATH-CRC Web app

This is an open label, Phase 1/2, first-in-human, multiple ascending dose, and dose-expansion study of IDP-023 administered as a single agent and in...

Enrolling
Multiple Myeloma
Refractory Multiple Myeloma
Drug: IDP-023
Drug: Interleukin-2

The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of moderate or severe migraine in children and adolesc...

Enrolling
Acute Treatment of Migraine
Drug: Rimegepant / BHV3000

This is an open-label, long-term extension study to investigate the safety, tolerability and efficacy of DISC-1459 in participants with EPP.

Invitation-only
Erythropoietic Protoporphyria
Drug: DISC-1459

The purpose of this post-market study is to evaluate changes in pain and neurological function with high frequency, 10 kHz spinal cord stimulation (S...

Enrolling
Painful Diabetic Neuropathy
Device: 10 kHz SCS
Other: CMM alone

The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in chil...

Enrolling
Pediatric Migraine
Drug: Rimegepant/BHV3000
Drug: Matching placebo

This phase 2 trial studies the immune response to GEO-CM04S1 (previously designated as COH04S1) compared to standard of care (SOC) mRNA SARS-COV-2 va...

Enrolling
Plasma Cell Myeloma
Lymphoma
Biological: Synthetic MVA-based SARS-CoV-2 Vaccine GEO-CM04S1
Other: Diagnostic Laboratory Biomarker Analysis

This phase 1b/2a open-label study will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of DISC-0974 as well as categorize the...

Enrolling
Anemia
Myelofibrosis
Drug: DISC-0974

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surg...

Enrolling
Triple Negative Breast Cancer
Drug: Capecitabine
Drug: Sacituzumab govitecan-hziy (SG)
Locations recently updated

Randomized, open-label, multi-center, comparative trial to assess the efficacy and safety in immunocompromised subjects with acyclovir resistant or a...

Enrolling
HSV Infection
Drug: Investigator's choice
Drug: Pritelivir

Trial sponsors

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