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Cancer and Blood Specialty Clinic | Los Alamitos, CA

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Top treatments

Amivantamab
Sacituzumab
Pembrolizumab
Abemaciclib
sigvotatug vedotin
Bevacizumab
Lazertinib
Docetaxel
LY2835219
Atezolizumab

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Active trials

28 of 35 total trials

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) (CYCLONE 3)

The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse....

Active, not recruiting
Cytochrome P-450
Antineoplastic Agents, Hormonal
Drug: Placebo for Abemaciclib
Drug: Abemaciclib

The purpose of this study is to compare how long the participants are disease-free (progression-free survival) and and the length of time until a par...

Enrolling
Colorectal Neoplasms
Drug: Leucovorin calcium/Levoleucovorin
Biological: Amivantamab

The purpose of this study is to compare how long the participants are disease-free (progression-free survival) when treated with amivantamab and chem...

Enrolling
Colorectal Neoplasms
Biological: Cetuximab
Biological: Amivantamab

The primary purpose of the study is to assess how well amivantamab subcutaneous (SC) administration in combination with lazertinib or in combination...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Chemotherapy: Carboplatin
Drug: Chemotherapy: Pemetrexed

The primary purpose of the Dose Optimization (Part 1) of this study is to assess the safety and tolerability of BB-1701 and to determine the recommen...

Enrolling
Breast Cancer
Drug: BB-1701

The purpose of this study is to identify the recommended Phase 2 (combination) dose (RP2CD) of the amivantamab and cetrelimab combination therapy in...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Amivantamab
Drug: Cetrelimab

The purpose of this study is to identify the recommended Phase 2 (combination) dose (RP2CD) of the amivantamab and docetaxel combination therapy in p...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Amivantamab
Drug: Docetaxel

This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it...

Enrolling
Uterine Cervical Neoplasms
Ovarian Neoplasms
Drug: carboplatin
Drug: pembrolizumab

This clinical trial is studying nonsquamous non-small cell lung cancer (NSCLC). Participants in this study must have cancer that has spread through t...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: sigvotatug vedotin
Drug: docetaxel

This study is about a medicine called TAK-788, also known as mobocertinib, given to adults with non-small cell lung cancer. The main aims of this stu...

Active, not recruiting
Carcinoma, Non-Small-Cell Lung
Drug: TAK-788
Locations recently updated

The purpose of the study is to compare the efficacy of zanubrutinib plus obinutuzumab versus lenalidomide plus rituximab (R\^2) in participants with...

Enrolling
Relapsed/Refractory Follicular Lymphoma
Marginal Zone Lymphoma
Drug: Rituximab
Drug: Lenalidomide
Locations recently updated

The purpose of this study is to evaluate the efficacy and safety of Luspatercept when administered at the maximum approved dose in low-risk Myelodysp...

Enrolling
Myelodysplastic Syndromes
Drug: Luspatercept

The purpose of this study is to evaluate the efficacy and safety of ibrutinib + venetoclax (I+V) and ibrutinib monotherapy regimens in which dosing o...

Enrolling
Small Lymphocytic Lymphoma
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: Venetoclax
Drug: Ibrutinib

The purpose of this study is to compare the efficacy and safety of mezigdomide (CC-92480), bortezomib and dexamethasone (MeziVd) versus pomalidomide,...

Enrolling
Relapsed or Refractory Multiple Myeloma
Drug: Pomalidomide
Drug: mezigdomide

This study will evaluate the effect of adding abemaciclib to fulvestrant for the treatment of hormone receptor-positive (HR+), human epidermal growth...

Active, not recruiting
Breast Neoplasm
Neoplasm Metastasis
Drug: Fulvestrant
Drug: Placebo

The main purpose of this study is to learn if the usual chemotherapy given before surgery (neoadjuvant therapy) for breast cancer plus the experiment...

Active, not recruiting
Triple Negative Breast Cancer
Drug: Atezolizumab
Drug: Placebo

The purpose of the study is to compare the efficacy and safety of Luspatercept vs epoetin alfa in the treatment of anemia in adults due to IPSS-R ver...

Enrolling
Myelodysplastic Syndromes
Biological: Epoetin Alfa
Biological: Luspatercept

The purpose of this study is to evaluate whether enhanced dermatologic management can reduce incidence of grade greater than or equal to (\>=) 2 derm...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Chlorhexidine
Drug: Doxycycline

This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbocic...

Enrolling
Breast Cancer
Drug: Alpelisib
Drug: Fulvestrant

This study is a first-in-human, Phase 1a/1b, multicenter, open-label study to determine the safety, tolerability, and pharmacokinetics of aplitabart...

Active, not recruiting
Solid Tumor
Chondrosarcoma
Drug: Docetaxel
Drug: Aplitabart (IGM-8444)

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