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Cancer and Blood Specialty Clinic | Los Alamitos, CA

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Top treatments

Pembrolizumab
Sacituzumab
Amivantamab
sigvotatug vedotin
Abemaciclib
Bevacizumab
Docetaxel
Lazertinib
LY2835219
Atezolizumab

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Active trials

35 of 43 total trials

A Clinical Study of Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) to Treat Newly-diagnosed Metastatic Non-small Cell Lung Cancer (MK-3475A-F84)

Researchers are looking for new ways to treat non-small cell lung cancer (NSCLC) that is metastatic, which means cancer has spread to other parts of...

Enrolling
Lung Cancer
Non-Small Cell Lung Cancer
Biological: Pembrolizumab
Biological: Pembrolizumab (+) Berahyaluronidase alfa

The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse....

Active, not recruiting
Cytochrome P-450
Antineoplastic Agents, Hormonal
Drug: Placebo for Abemaciclib
Drug: Abiraterone

The purpose of this study is to compare how long the participants are disease-free (progression-free survival) and and the length of time until a par...

Enrolling
Colorectal Neoplasms
Drug: Leucovorin calcium/Levoleucovorin
Biological: Amivantamab

The purpose of this study is to compare how long the participants are disease-free (progression-free survival) when treated with amivantamab and chem...

Enrolling
Colorectal Neoplasms
Biological: Cetuximab
Biological: Amivantamab

The primary purpose of the study is to assess how well amivantamab in combination with lazertinib or in combination with chemotherapy works (antitumo...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Chemotherapy: Carboplatin
Drug: Lazertinib

The primary purpose of the Dose Optimization (Part 1) of this study is to assess the safety and tolerability of BB-1701 and to determine the recommen...

Active, not recruiting
Breast Cancer
Drug: BB-1701

The purpose of this study is to identify the recommended Phase 2 (combination) dose (RP2CD) of the amivantamab and cetrelimab combination therapy in...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Amivantamab
Drug: Cetrelimab

The purpose of this study is to identify the recommended Phase 2 (combination) dose (RP2CD) of the amivantamab and docetaxel combination therapy in p...

Active, not recruiting
Carcinoma, Non-Small-Cell Lung
Drug: Amivantamab
Drug: Docetaxel
Locations recently updated

The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physici...

Enrolling
Breast Neoplasms
Drug: Liposomal doxorubicin
Drug: Sacituzumab tirumotecan

This clinical trial is studying nonsquamous non-small cell lung cancer (NSCLC). Participants in this study must have cancer that has spread through t...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: sigvotatug vedotin
Drug: docetaxel

This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it...

Enrolling
Uterine Cervical Neoplasms
Ovarian Neoplasms
Drug: carboplatin
Drug: pembrolizumab

This study is about a medicine called TAK-788, also known as mobocertinib, given to adults with non-small cell lung cancer. The main aims of this stu...

Active, not recruiting
Carcinoma, Non-Small-Cell Lung
Drug: TAK-788

The purpose of the study is to compare the efficacy of zanubrutinib plus obinutuzumab versus lenalidomide plus rituximab (R\^2) in participants with...

Enrolling
Relapsed/Refractory Follicular Lymphoma
Marginal Zone Lymphoma
Drug: Rituximab
Drug: Lenalidomide

The purpose of this study is to evaluate the efficacy and safety of Luspatercept when administered at the maximum approved dose in low-risk Myelodysp...

Enrolling
Myelodysplastic Syndromes
Drug: Luspatercept
Locations recently updated

The primary objective of this study is to compare the efficacy of ABP 234 with the pembrolizumab reference product (Keytruda®).

Enrolling
Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer
Drug: ABP 234
Drug: Pembrolizumab (EU)

The purpose of this study is to compare the efficacy and safety of BMS-986365 versus the investigator's choice of therapy in participants with Metast...

Enrolling
Metastatic Castration-resistant Prostate Cancer
Drug: Docetaxel
Drug: Abiraterone

The purpose of this study is to evaluate the efficacy and safety of ibrutinib + venetoclax (I+V) and ibrutinib monotherapy regimens in which dosing o...

Enrolling
Small Lymphocytic Lymphoma
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: Venetoclax
Drug: Ibrutinib

The purpose of this study is to compare the efficacy and safety of mezigdomide (CC-92480), bortezomib and dexamethasone (MeziVd) versus pomalidomide,...

Enrolling
Relapsed or Refractory Multiple Myeloma
Drug: Pomalidomide
Drug: mezigdomide

This study is designed to assess the levels of drug exposure following treatment with tislelizumab administered as a subcutaneous (SC) injection comp...

Begins enrollment in 1 month
Metastatic Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Drug: 5-fluorouracil (5-FU)
Drug: Cisplatin

This study is researching an experimental drug called fianlimab (also known as REGN3767), combined with another medication called cemiplimab (also kn...

Enrolling
Melanoma
Drug: fianlimab
Drug: cemiplimab

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