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Cancer and Blood Specialty Clinic | Los Alamitos, CA

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Top conditions

Top treatments

Amivantamab
sigvotatug vedotin
Pembrolizumab
Abemaciclib
Sacituzumab
Docetaxel
LY2835219
MT-5111
Clindamycin
Atezolizumab

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Active trials

24 of 30 total trials

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) (CYCLONE 3)

The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse....

Active, not recruiting
Cytochrome P-450
Antineoplastic Agents, Hormonal
Drug: Placebo for Abemaciclib
Drug: Abemaciclib

The primary purpose of the Dose Optimization (Part 1) of this study is to assess the safety and tolerability of BB-1701 and to determine the recommen...

Enrolling
Breast Cancer
Drug: BB-1701

The purpose of this study is to identify the recommended Phase 2 (combination) dose (RP2CD) of the amivantamab and cetrelimab combination therapy in...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Amivantamab
Drug: Cetrelimab

The purpose of this study is to identify the recommended Phase 2 (combination) dose (RP2CD) of the amivantamab and docetaxel combination therapy in p...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Amivantamab
Drug: Docetaxel

This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it...

Enrolling
Uterine Cervical Neoplasms
Ovarian Neoplasms
Drug: carboplatin
Drug: pembrolizumab
Locations recently updated

This clinical trial is studying nonsquamous non-small cell lung cancer (NSCLC). Participants in this study must have cancer that has spread through t...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: sigvotatug vedotin
Drug: docetaxel

This study is about a medicine called TAK-788, also known as mobocertinib, given to adults with non-small cell lung cancer. The main aims of this stu...

Active, not recruiting
Carcinoma, Non-Small-Cell Lung
Drug: TAK-788

The purpose of the study is to compare the efficacy of zanubrutinib plus obinutuzumab versus lenalidomide plus rituximab (R\^2) in participants with...

Enrolling
Relapsed/Refractory Follicular Lymphoma
Marginal Zone Lymphoma
Drug: Rituximab
Drug: Lenalidomide

The purpose of this study is to evaluate the efficacy and safety of Luspatercept when administered at the maximum approved dose in low-risk Myelodysp...

Enrolling
Myelodysplastic Syndromes
Drug: Luspatercept
Locations recently updated

The purpose of this study is to compare the efficacy and safety of mezigdomide (CC-92480), bortezomib and dexamethasone (MeziVd) versus pomalidomide,...

Enrolling
Relapsed or Refractory Multiple Myeloma
Drug: Pomalidomide
Drug: mezigdomide

This study will evaluate the effect of adding abemaciclib to fulvestrant for the treatment of hormone receptor-positive (HR+), human epidermal growth...

Active, not recruiting
Breast Neoplasm
Neoplasm Metastasis
Drug: Fulvestrant
Drug: Placebo

The main purpose of this study is to learn if the usual chemotherapy given before surgery (neoadjuvant therapy) for breast cancer plus the experiment...

Active, not recruiting
Triple Negative Breast Cancer
Drug: Atezolizumab
Drug: Placebo
Locations recently updated

The purpose of the study is to compare the efficacy and safety of Luspatercept vs epoetin alfa in the treatment of anemia in adults due to IPSS-R ver...

Enrolling
Myelodysplastic Syndromes
Biological: Epoetin Alfa
Biological: Luspatercept

The purpose of this study is to evaluate whether enhanced dermatologic management can reduce incidence of grade greater than or equal to (\>=) 2 derm...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Chlorhexidine
Drug: Doxycycline

This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbocic...

Enrolling
Breast Cancer
Drug: Alpelisib
Drug: Fulvestrant

This study is a first-in-human, Phase 1a/1b, multicenter, open-label study to determine the safety, tolerability, and pharmacokinetics of aplitabart...

Active, not recruiting
Solid Tumor
Chondrosarcoma
Drug: Docetaxel
Drug: Aplitabart (IGM-8444)

This study will compare the efficacy of the investigational agent sitravatinib in combination with nivolumab versus docetaxel in patients with advanc...

Active, not recruiting
Metastatic Non-Squamous Non-Small Cell Lung Cancer
Drug: Sitravatinib
Drug: Docetaxel

The goal of this clinical trial is to evaluate the safety and tolerability of escalating doses of LP-284 and to determine the maximum tolerated dose...

Enrolling
Relapsed or Refractory Lymphomas
Advanced Solid Tumor
Drug: LP-284

The primary objective of this study is to evaluate the safety, tolerability, MTD and RP2D of LP-184 in patients with advanced solid tumors who have r...

Enrolling
Advanced Solid Tumor
Drug: LP-184

The primary objective of this study is to assess the efficacy of 2 different doses of onvansertib in combination with a chemotherapy regimen of irino...

Active, not recruiting
Metastatic Colorectal Cancer
Colorectal Cancer
Drug: Bevacizumab
Drug: Onvansertib

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