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Intrepid Research | Cincinnati, OH

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Top treatments

Pitolisant
JZP-258
TAK-861
Mazindol
Acetazolamide
HBS-301
Atomoxetine
AD504
Lemborexant
Lorundrostat

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Active trials

8 of 40 total trials
Locations recently updated

A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

This is a Phase 3, multicenter, randomized, double-blind, parallel-group, placebo-controlled clinical study to assess the efficacy and safety of HBS-...

Enrolling
Idiopathic Hypersomnia
Drug: HBS-301 tablet
Drug: Placebo
Locations recently updated

This is a Phase 3, multicenter, randomized, double-blind, parallel-group, placebo-controlled clinical study to assess the efficacy and safety of HBS-...

Enrolling
Cataplexy
EDS
Drug: HBS-301
Other: Placebo

The purpose of this study is to evaluate the efficacy and safety of expanded Xywav dosing regimens in adult participants with narcolepsy or idiopathi...

Not yet enrolling
Idiopathic Hypersomnia
Narcolepsy
Drug: Xywav
Other: Placebo

The main aim is to evaluate the safety and tolerability of TAK-861 in participants with type 1 narcolepsy, who were exposed to previously tested dose...

Enrolling
Narcolepsy Type 1
Drug: TAK-861

The combination drug composed of aroxybutynin and atomoxetine, designated AD109, is being developed by Apnimed for the treatment of obstructive sleep...

Invitation-only
OSA
Drug: Aroxybutynin and Atomoxetine
Locations recently updated

The goal of this randomized, double-blind, multi-dose crossover clinical trial is to determine the safety and efficacy of IHL-42X in subjects with ob...

Enrolling
Obstructive Sleep Apnea (OSA)
Drug: Placebo: Negative control
Drug: IHL-42X: 2.5 mg dronabinol + 125 mg acetazolamide

This study is to evaluate the long-term safety, efficacy and tolerability of lorundrostat (an aldosterone synthase inhibitor) in subjects with hypert...

Active, not recruiting
Hypertension
Drug: lorundrostat
Drug: Placebo

The primary purpose of this study is to evaluate the effectiveness of sivopixant, acetazolamide and SASS-001 in adults with sleep apnea with a centra...

Active, not recruiting
Sleep Apnea
Drug: SASS-001
Drug: Placebo

Trial sponsors

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