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Clinical Trials of Texas | San Antonio, TX

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Active trials

33 of 305 total trials
Locations recently updated

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

Researchers designed a study medicine called enlicitide to lower low-density lipoprotein cholesterol (LDL-C). In this study, researchers want to lear...

Enrolling
Hyperlipidemia
Drug: Placebo for Rosuvastatin
Drug: Enlicitide

The objective is to evaluate the safety and efficacy of low dose and high dose CBT-001 eye drop dosed twice daily for 24 months compared to vehicle i...

Active, not recruiting
Pterygium
Drug: CBT-001
Drug: Vehicle

This is a randomized, dose-escalation Phase I/IIa trial to evaluate safety, tolerability, immunogenicity and efficacy of an investigational RNA-based...

Active, not recruiting
Malaria
Biological: BNT165e
Other: Placebo

This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (semaglutide)

The main purpose of this study is to evaluate the safety and tolerability of the study drug LY3849891 in participants with metabolic dysfunction-asso...

Active, not recruiting
Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Drug: Placebo
Drug: LY3849891

A Phase 2 in Patients With Mixed Dyslipidemia

Active, not recruiting
Mixed Dyslipidemia
Drug: BW-00112

The purpose of this study is to determine the efficacy, safety and tolerability of CYB003 compared to matching placebo as adjunctive treatment in pat...

Enrolling
Depression in Adults
Depression Disorders
Drug: CYB003
Behavioral: Psychological Support

The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabete...

Active, not recruiting
Chronic Kidney Disease
Overweight
Drug: Orforglipron
Drug: Insulin Glargine

The main purpose of this study is to determine the safety and efficacy of DII235 in adults with elevated lipoprotein(a).

Enrolling
Lipoprotein Disorder
Drug: Saline
Drug: DII235

The purpose of this study is to assess the effect of JNJ-64042056 on cognitive decline, as measured by Preclinical Alzheimer's disease Cognitive Comp...

Enrolling
Preclinical Alzheimer's Disease
Drug: JNJ-64042056
Drug: Placebo

The main purpose of this study is to look at how safe the study drug (mevidalen) is and whether it works to alleviate symptoms when given to people w...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: Mevidalen

This study will investigate the effect of tirzepatide on the reduction of morbidity and mortality in adults living with obesity and provide additiona...

Active, not recruiting
Overweight
Obesity
Drug: Placebo
Drug: Tirzepatide

The purpose of this study is to evaluate the efficacy, safety and tolerability of QCZ484 or placebo, given subcutaneously, every 6 months, at differe...

Enrolling
Hypertension
Drug: QCZ484
Other: Saline

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The purpose of this study is to learn about the safety and immune effects of a pneumococcal vaccine in adults. This vaccine can possibly provide prot...

Active, not recruiting
Pneumococcal Disease
Biological: 20-valent pneumococcal conjugate vaccine (20vPnC)
Biological: Multivalent Pneumococcal Vaccine - Formulation 2

To evaluate long-term safety exposure

Active, not recruiting
Attention Deficit/Hyperactivity Disorder
Drug: Centanafadine Hydrochloride

The study consists of 24-week double-blind trial to evaluate the non-inferiority of the efficacy and safety of pegloticase Q4W with MTX versus peglot...

Active, not recruiting
Gout
Drug: Methotrexate
Biological: Pegloticase

A Prospective, Multicenter Evaluation of Accuracy and Safety of the Eversense CGM System with Enhanced Features. The purpose of this clinical investi...

Enrolling
Diabetes Mellitus, Type 1
Diabetes Mellitus
Device: Continuous Glucose Monitoring System

The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.

Active, not recruiting
Obesity
Drug: Placebo
Drug: Maridebart Cafraglutide

The goal of this clinical trial is to learn if GATE-251 works to treat depression in adults. It will also learn about the safety of GATE-251. The mai...

Enrolling
Major Depressive Disorder
Drug: Zelquistinel

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