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Paclitaxel
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Active trials

14 of 84 total trials

A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

This is a phase 1, multicenter, open-label study evaluating the safety and efficacy of ruxolitinib, steroids and lenalidomide among MM patients who c...

Enrolling
Multiple Myeloma
Drug: Ruxolitinib Oral Tablet [Jakafi]
Drug: Methylprednisolone

The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered...

Enrolling
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: Gemcitabine
Drug: AMG 193

The main purpose of this study is to evaluate how safe and effective the study drug known as abemaciclib is in participants with lung cancer.

Active, not recruiting
Non Small Cell Lung Cancer
Drug: Erlotinib
Drug: Abemaciclib

The main purpose of this study is to evaluate how effective nonsteroidal aromatase inhibitors (NSAI) plus abemaciclib are in postmenopausal women wit...

Active, not recruiting
Breast Cancer
Drug: Abemaciclib
Drug: Anastrozole

The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for ca...

Active, not recruiting
Metastatic Adenocarcinoma of the Pancreas
Drug: Leucovorin
Drug: Gemcitabine

A study to learn about a new medicine called ARV-471 (PF-07850327) in people who have advanced metastatic breast cancer.

Active, not recruiting
Advanced Breast Cancer
Drug: ARV-471
Drug: Fulvestrant

The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered...

Enrolling
Non-small Cell Lung Cancer
Thoracic Tumors
Drug: Carboplatin
Drug: Pemetrexed

The purpose of this study is to continue to provide elotuzumab and/or other study drugs to participants who have participated on a prior protocol inv...

Active, not recruiting
Multiple Myeloma
Drug: Pomalidomide
Drug: Dexamethasone

This study is designed to assess the efficacy and safety of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab versus pembrolizumab...

Enrolling
Metastatic Non Small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Carboplatin

Primary Objective:To determine whether amcenestrant per overall survival (os) improves progression free survival (PFS) when compared with an endocrin...

Active, not recruiting
Breast Cancer Metastatic
Drug: Tamoxifen
Drug: Anastrozole

This is a prospective, randomized, double-blinded, placebo-controlled, multi-center, Phase 3 study of GLSI-100 immunotherapy in HLA-A\*02 positive an...

Enrolling
Breast Cancer
Biological: Placebo
Biological: GLSI-100

GIM-531 is a first-in-class, orally bioavailable small molecule that is being developed for the treatment of advanced solid tumors as a single agent...

Enrolling
Solid Tumor
Melanoma Stage IV
Drug: GIM-531
Drug: Anti-PD-1 monoclonal antibody

This is a clinical study to compare the efficacy and safety of HBI-8000 combined with nivolumab to Placebo combined with nivolumab in patients with u...

Active, not recruiting
Progressive Brain Metastasis
Unresectable or Metastatic Melanoma
Drug: Placebo in combination with nivolumab
Drug: HBI-8000 in combination with nivolumab

Tomivosertib combined with pembrolizumab in Subjects with PD-L1 positive NSCLC

Active, not recruiting
Non-small Cell Lung Cancer
Biological: Pembrolizumab
Drug: Pemetrexed

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