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Evolution Research Group | Clinical Pharmacology of Miami

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Top treatments

CTP-543
Risankizumab
SSP-004184
Tirzepatide
SPD602
LY3502970
Isavuconazole
LY3298176
Mirikizumab
BMS-986177

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Active trials

12 of 210 total trials

A First-in-human, 3-part Study of MRT-8102 in Healthy Participants and Participants at Cardiovascular Risk With Elevated CRP

The principal aim of this study is to obtain safety and tolerability data when MRT-8102 is administered orally as single and multiple doses to health...

Active, not recruiting
Healthy Volunteers
Elevated CRP
Drug: Placebo
Drug: MRT-8102

The study is to assess the safety, pharmacokinetics, and pharmacodynamic profile of HMS1005 in patient with diabetes

Enrolling
Type 2 Diabetes
Drug: HMS1005
Drug: Matching placebo

This is a 4-part study that includes a Part A, Part B, Part C, and Part D. Parts A and D will study the safety and tolerability of the study drug kno...

Active, not recruiting
Overweight
Obesity
Drug: Placebo
Drug: LY3537031

The main purpose of this study is to learn more how tirzepatide affects stomach emptying in participants with Type 1 Diabetes Mellitus (T1DM) and ove...

Not yet enrolling
Diabetes Mellitus, Type 1
Overweight
Drug: Tirzepatide
Drug: Acetaminophen

This is a Phase 3, randomized, double-blind, comparator- and placebo-controlled study to evaluate analgesic efficacy and safety of TLC590 via local i...

Active, not recruiting
Postoperative Pain
Drug: Saline Placebo
Drug: Liposomal Bupivacaine

This study is to assess how oral emraclidine moves through the body of healthy elderly adult participants, and assess adverse events, and tolerabilit...

Enrolling
Healthy Volunteer
Drug: Placebo
Drug: Emraclidine

The purpose of the study is to look at how the body processes a study medicine called vepdegestrant in participants with loss of liver function relat...

Enrolling
Healthy Participants
Drug: vepdegestrant

This study will evaluate and compare the PK in subjects with severe HI to that of matched healthy control subjects with normal hepatic function.

Enrolling
Hepatic Impairment
Drug: Quizartinib
Recently updated

The purposes of this study are to determine:* The pharmacokinetics (the amount of study drug in your blood and how long it takes the body to get rid...

Enrolling
Hepatic Impairment
Healthy
Drug: Mirdametinib (MEK Inhibitor)

This is a First in Human study to evaluate the safety and tolerability of DA-1726 following single and multiple doses in participants with obesity, b...

Enrolling
Obesity
Drug: DA-1726
Drug: Placebo to DA-1726

The primary objective of this study is to assess the safety and tolerability of AMG 513 after single and multiple doses.

Active, not recruiting
Cardiometabolic Disease
Drug: Placebo
Drug: AMG 513

A Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants with or without Type 2 Diabetes

Enrolling
Overweight or Obese, Type 2 Diabetes
Overweight or Obese Adults
Drug: Placebo
Drug: ALV-100

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