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Evolution Research Group | Clinical Pharmacology of Miami

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CTP-543
SSP-004184
Risankizumab
SPD602
Isavuconazole
SSP-004184SS
DA-1241
Navocaftor
Levoketoconazole
Metformin

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Active trials

15 of 181 total trials

A Bioequivalence Study of Citrate Free Mirikizumab (LY3074828) in Healthy Participants

The purpose of this study is to evaluate the amount of mirikizumab (test) that gets into the blood stream and how long it takes the body to get rid o...

Active, not recruiting
Healthy
Drug: Citrate-Free Mirikizumab

The goals of this study are to compare the amount of study drug, bulevirtide (BLV), that gets into the bloodstream and how long it takes for the body...

Enrolling
Chronic Hepatitis D Infection
Drug: Bulevirtide (BLV)

Evaluate simufilam levels in the blood of hepatically impaired individuals compared to Healthy individuals of similar demographics

Enrolling
Hepatic Insufficiency
Drug: Simufilam

A Phase 1, First-in-human, Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Study in Healthy Adults and Open-label Si...

Invitation-only
Alzheimer Disease
Healthy
Drug: VG-3927
Drug: Placebo

The purpose of this study is to evaluate the pharmacokinetics of efinopegdutide in participants with hepatic impairment compared to healthy participa...

Enrolling
Hepatic Impairment
Non-alcoholic Steatohepatitis
Drug: Efinopegdutide

The main purpose of this study is to measure how much of LY3502970 gets into the bloodstream and how long it takes the body to eliminate it in partic...

Enrolling
Healthy
Hepatic Insufficiency
Drug: LY3502970
New

The purpose of the study is to learn about the safety of MK-2225, including how well people tolerate it. Researchers also want to learn what happens...

Active, not recruiting
Systemic Sclerosis
Other: Placebo
Drug: MK-2225

The purpose of this study is to compare the plasma pharmacokinetics (PK) of nemabrutinib (MK-1026) following a single oral dose of nemtabrutinib in p...

Enrolling
Hepatic Impairment (HI)
Drug: Nemtabrutinib

The objective of this study is to compare pharmacokinetic exposures following intravenous and subcutaneous administration of Risankizumab.

Active, not recruiting
Healthy Volunteers
Drug: Risankizumab

The purpose of the study is to learn about:* how PF-07817883 is processed in the body of adult participants.* the safety of PF-07817883.These partici...

Enrolling
COVID-19
Drug: PF-07817883

This study is open to adults with overweight or obesity who also have fatty liver disease. The purpose of this study is to find the highest dose of B...

Active, not recruiting
Obesity
Non-alcoholic Fatty Liver Disease
Drug: BI 3006337
Drug: Placebo matching BI 3006337

This is a First in Human study to evaluate the safety and tolerability of DA-1726 following single and multiple doses in participants with obesity, b...

Enrolling
Obesity
Drug: Placebo to DA-1726
Drug: DA-1726

A phase 2b, multicenter, randomized, double-blind, placebo-controlled study of HTD1801 in adult subjects with non-alcoholic steatohepatitis and liver...

Active, not recruiting
Nonalcoholic Steatohepatitis (NASH)
Type 2 Diabetes
Drug: Placebo
Drug: HTD1801

The goals of this study are to measure the amount of bulevirtide (BLV) that gets into the blood stream and how long it takes to get rid of it, measur...

Enrolling
Chronic Hepatitis D Infection
Drug: Bulevirtide

A multicenter, randomized, double-blind, placebo-controlled, parallel, Phase 2a clinical trial to evaluate the efficacy and safety of DA 1241 in subj...

Active, not recruiting
NON-ALCOHOLIC STEATOHEPATITIS
Drug: Sitagliptin
Drug: DA-1241 Placebo

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