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Hospital Universitario de Salamanca | Medicina Interna - Ensayos Clinicos

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Active trials

88 of 283 total trials

A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433 (U-ENDURE)

A multicenter study to evaluate the efficacy and safety of maintenance and long-term treatment administration of upadacitinib, an orally administered...

Active, not recruiting
Crohn's Disease
Drug: Placebo for Upadacitinib
Drug: Upadacitinib

The main aims of this 2-part study are:* Phase I: To determine the maximum tolerated dose (MTD) and the recommended phase 2 dose (RP2D) of IDP-121 in...

Enrolling
Multiple Myeloma (MM)
High Grade B-Cell Lymphoma, Not Otherwise Specified
Drug: IDP-121

The purpose of this trial is to find out if epcoritamab, also known as EPKINLY™ and GEN3013, is safe and works well as treatment for patients with di...

Active, not recruiting
Diffuse Large B-cell Lymphoma
Drug: Investigator's Choice Chemotherapy
Biological: Epcoritamab

A study designed to evaluate the non-inferiority of crovalimab compared with eculizumab in participants with PNH who have not been previously treated...

Active, not recruiting
Paroxysmal Nocturnal Hemoglobinuria
Drug: Eculizumab
Drug: Crovalimab

This is a multi-center phase III study to compare the clinical benefit of androgen deprivation therapy with or without docetaxel with or without loca...

Active, not recruiting
Metastatic Prostate Cancer
Other: Androgen Deprivation Therapy
Drug: abiraterone acetate

This study is researching an investigational drug called linvoseltamab ("study drug") in participants at high risk of developing multiple myeloma (MM...

Enrolling
Smoldering Multiple Myeloma (SMM)
Drug: Linvoseltamab

The study is being done to see if ziltivekimab can be used to treat participants living with heart failure and inflammation. Participants will either...

Enrolling
Systemic Inflammation
Heart Failure
Drug: Placebo
Drug: Ziltivekimab

This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX110 in subjects with relapsed or refractory B-cell malig...

Active, not recruiting
Adult B Cell ALL
B-cell Lymphoma
Biological: CTX110

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX120 in subjects with relapsed or refractory mul...

Active, not recruiting
Multiple Myeloma
Biological: CTX120

he purpose of the study is to evaluate the efficacy, safety, and tolerability BGB-3111 plus obinutuzumab versus obinutuzumab alone in participants wi...

Active, not recruiting
Relapsed/Refractory Follicular Non-Hodgkin Lymphoma
Drug: Zanubrutinib
Drug: Obinutuzumab

A study designed tocompare progression-free survival (PFS) in participants with t(11;14)-positive MM treated with venetoclax in combination with dexa...

Active, not recruiting
Multiple Myeloma
Drug: Pomalidomide
Drug: Venetoclax
Status recently updated

A study designed to evaluate the safety of crovalimab with eculizumab in participants with PNH currently treated with complement inhibitors. This stu...

Active, not recruiting
Enrolling
Paroxysmal Nocturnal Hemoglobinuria
Drug: Eculizumab
Drug: Crovalimab

The study will determine the safety, tolerability, recommended Phase 2 dose (RP2D) and preliminary efficacy of BGB-11417 as monotherapy and in combin...

Enrolling
Myelodysplastic Syndromes
Myelodysplastic/Myeloproliferative Neoplasm
Drug: Azacitidine
Drug: BGB-11417

This phase 3 randomized, open-label multicenter trial will compare the efficacy, safety and the impact on health-related quality of life (HR-QoL) of...

Enrolling
Multiple Myeloma
Drug: Selinexor
Drug: Elotuzumab

First-in-human, open-label, sequential dose escalation and expansion study of CPI-0209 in patients with advanced solid tumors and lymphomas. CPI-0209...

Enrolling
Endometrial Cancer
Lymphoma, T-Cell
Drug: CPI-0209

The purpose of this study is to compare the efficacy of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Ciltacabtagene Aut...

Enrolling
Multiple Myeloma
Drug: Fludarabine
Drug: Daratumumab

A Phase 1/2 dose escalation / dose expansion study of DSP 5336 in patients with relapsed or refractory AML.

Enrolling
Leukemia, Lymphocytic, Acute
Leukemia, Myeloid, Acute
Drug: DSP-5336

This Phase 1/2 clinical study will evaluate evorpacept (ALX148) in combination with azacitidine for the treatment of patients with higher risk myelod...

Active, not recruiting
Higher Risk Myelodysplastic Syndromes
Drug: evorpacept
Drug: azacitidine

An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced...

Enrolling
Isocitrate Dehydrogenase Gene Mutation
Drug: HMPL-306

The purpose of this study is to evaluate the effects of KER-050 on anemia in patients with very low, low or intermediate risk MDS.

Enrolling
Cytopenia
Myelodysplastic Syndromes
Drug: KER-050

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