Hospital Universitario de Salamanca | Medicina Interna - Ensayos Clinicos

Research site
5ª Planta (aula). Paseo san Vicente 58-182, Salamanca, Salamanca, Spain

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Active trials

92 of 281 total trials

A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433

A multicenter study to evaluate the efficacy and safety of maintenance and long-term treatment administration of upadacitinib, an orally administered...

Active, not recruiting
Crohn's Disease
Drug: Upadacitinib
Drug: Placebo for Upadacitinib

An open-label, Phase 1 study of HPN217 to assess the safety, tolerability and PK in patients with relapsed/ refractory multiple myeloma

Active, not recruiting
Multiple Myeloma of Bone
Multiple Myeloma in Relapse
Drug: HPN217

The main aims of this 2-part study are:* Phase I: To determine the maximum tolerated dose (MTD) and the recommended phase 2 dose (RP2D) of IDP-121 in...

Multiple Myeloma (MM)
High Grade B-Cell Lymphoma, Not Otherwise Specified
Drug: IDP-121

The purpose of this trial is to find out if epcoritamab, also known as EPKINLY™ and GEN3013, is safe and works well as treatment for patients with di...

Active, not recruiting
Diffuse Large B-cell Lymphoma
Drug: Investigator's Choice Chemotherapy
Biological: Epcoritamab

A study designed to evaluate the non-inferiority of crovalimab compared with eculizumab in participants with PNH who have not been previously treated...

Active, not recruiting
Paroxysmal Nocturnal Hemoglobinuria
Drug: Eculizumab
Drug: Crovalimab

This is a multi-center phase III study to compare the clinical benefit of androgen deprivation therapy with or without docetaxel with or without loca...

Active, not recruiting
Metastatic Prostate Cancer
Drug: Docetaxel
Radiation: radiotherapy

This study is researching an investigational drug called linvoseltamab ("study drug") in participants at high risk of developing multiple myeloma (MM...

Smoldering Multiple Myeloma (SMM)
Drug: Linvoseltamab

The study is being done to see if ziltivekimab can be used to treat participants living with heart failure and inflammation. Participants will either...

Systemic Inflammation
Heart Failure
Drug: Placebo
Drug: Ziltivekimab

This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX110 in subjects with relapsed or refractory B-cell malig...

Active, not recruiting
Adult B Cell ALL
B-cell Lymphoma
Biological: CTX110

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX120 in subjects with relapsed or refractory mul...

Active, not recruiting
Multiple Myeloma
Biological: CTX120

he purpose of the study is to evaluate the efficacy, safety, and tolerability BGB-3111 plus obinutuzumab versus obinutuzumab alone in participants wi...

Active, not recruiting
Relapsed/Refractory Follicular Non-Hodgkin Lymphoma
Drug: Obinutuzumab
Drug: Zanubrutinib

A study designed tocompare progression-free survival (PFS) in participants with t(11;14)-positive MM treated with venetoclax in combination with dexa...

Active, not recruiting
Multiple Myeloma
Drug: Dexamethasone
Drug: Pomalidomide

A study designed to evaluate the safety of crovalimab with eculizumab in participants with PNH currently treated with complement inhibitors. This stu...

Paroxysmal Nocturnal Hemoglobinuria
Drug: Eculizumab
Drug: Crovalimab

The study will determine the safety, tolerability, recommended Phase 2 dose (RP2D) and preliminary efficacy of BGB-11417 as monotherapy and in combin...

Myelodysplastic Syndromes
Myelodysplastic/Myeloproliferative Neoplasm
Drug: BGB-11417
Drug: Posaconazole

This phase 3 randomized, open-label multicenter trial will compare the efficacy, safety and the impact on health-related quality of life (HR-QoL) of...

Multiple Myeloma
Drug: Pomalidomide
Drug: Elotuzumab

First-in-human, open-label, sequential dose escalation and expansion study of CPI-0209 in patients with advanced solid tumors and lymphomas. CPI-0209...

Endometrial Cancer
Lymphoma, T-Cell
Drug: CPI-0209

The purpose of this study is to compare the efficacy of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Ciltacabtagene Aut...

Multiple Myeloma
Drug: Fludarabine
Drug: Daratumumab

This Phase 1/2 clinical study will evaluate evorpacept (ALX148) in combination with azacitidine for the treatment of patients with higher risk myelod...

Active, not recruiting
Higher Risk Myelodysplastic Syndromes
Drug: evorpacept
Drug: azacitidine

An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced...

Isocitrate Dehydrogenase Gene Mutation
Drug: HMPL-306

The purpose of this study is to evaluate the safety and efficacy of two parsaclisib treatment regimens in participants diagnosed with relapsed or ref...

Active, not recruiting
Drug: Parsaclisib

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