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Pinnacle Research Group | Anniston, AL

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Active trials

38 of 165 total trials

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus (AMETHYST)

In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with cutaneous lupus erythematosus (CLE)....

Active, not recruiting
Subacute Cutaneous Lupus Erythematosus
Chronic Cutaneous Lupus Erythematosus
Drug: Litifilimab
Drug: Placebo

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon like peptide-1 (GLP-1)/glucose-dependent insulinotropi...

Enrolling
Obesity or Overweight
Combination Product: Enicepatide
Combination Product: Placebo

This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3

Active, not recruiting
NASH - Nonalcoholic Steatohepatitis
Drug: Placebo
Drug: IVA337

The purpose of this study is to compare the safety and efficacy of risankizumab versus placebo in participants with moderately to severely active pso...

Active, not recruiting
Psoriatic Arthritis
Biological: Placebo
Biological: Risankizumab

The purpose of this study is to evaluate the safety and reactogenicity of mRNA-1195 in healthy participants.

Active, not recruiting
Epstein-Barr Virus Infection
Biological: Placebo
Biological: mRNA-1195.1

The purpose of this study is to evaluate how well LY4213663 is tolerated and what side effects may occur in healthy participants and participants wit...

Enrolling
Rheumatoid Arthritis (RA)
Drug: LY4213663
Drug: Placebo
New

This study will evaluate the efficacy and safety of orforglipron in participants with overweight and assess whether it helps reduce the future risk o...

Not yet enrolling
Prehypertension
Prediabetic State
Drug: Orforglipron
Drug: Placebo

This study is designed to determine the effect of ulonivirine (MK-8507) on methadone in the body. Participants will take methadone alone and then met...

Not yet enrolling
Healthy
Drug: Ulonivirine
Drug: Methadone

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease characterized by B cell hyperactivity.Rheumatoid Arthritis (RA) is a chr...

Enrolling
Systemic Lupus Erythematosus
Rheumatoid Arthritis
Drug: ABBV-519

The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe System...

Active, not recruiting
Systemic Lupus Erythematosus
Other: Placebo
Drug: Deucravacitinib

The main aim of the study is to assess the effect of RO7204239 in combination with tirzepatide, compared to placebo in combination with tirzepatide,...

Active, not recruiting
Overweight
Obesity
Drug: Tirzepatide
Drug: RO7204239 Matching Placebo

This study will evaluate the efficacy and safety of astegolimab compared with placebo in participants with chronic obstructive pulmonary disease (COP...

Active, not recruiting
Chronic Obstructive Pulmonary Disease (COPD)
Drug: Astegolimab
Drug: Placebo

This parallel-group, double-blind, placebo-controlled study will evaluate the efficacy and safety of obinutuzumab versus placebo in participants with...

Active, not recruiting
Systemic Lupus Erythematosus
Drug: Methylprednisolone
Drug: Acetaminophen/Paracetamol

The purpose of this study is to evaluate how well CD388 works in preventing symptomatic laboratory-confirmed influenza infections, as compared to pla...

Active, not recruiting
Influenza
Combination Product: CD388 Injection
Combination Product: Placebo

The primary objective of the study is to determine the relative efficacy of the investigational oral severe acute respiratory syndrome coronavirus 2...

Active, not recruiting
COVID-19
SARS-CoV2
Biological: VXA-CoV2-3.1
Biological: VXA-CoV2-3.3

The main purpose of this study is to evaluate the efficacy and safety of Bimagrumab and Tirzepatide, alone or in combination, in adults with obesity...

Active, not recruiting
Overweight
Obesity
Drug: Tirzepatide Placebo
Drug: Bimagrumab

This study is designed to find out how well the COVID-19 vaccine protects people 50 to 64, who don't have any serious health problems, compared to a...

Active, not recruiting
COVID-19
SARS-COV-2 Infection
Biological: Placebo
Biological: BNT162b2 Vaccine

This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the t...

Enrolling
Hypercholesterolemia
Drug: Alirocumab
Recently updated

This study is researching experimental drugs called trevogrumab and garetosmab (called "study drugs") in combination with another drug, semaglutide (...

Active, not recruiting
Obesity
Drug: Matching Placebo-Trevogrumab
Drug: Matching Placebo-Garetosmab

This study is open to adults aged 18 or above legal age with heart failure. People can join the study if they have heart failure symptoms and a left...

Enrolling
Heart Failure
Drug: empagliflozin
Drug: placebo

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