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Active trials

5 of 13 total trials

Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Rest...

Enrolling
Heart Failure with Reduced Ejection Fraction (HFrEF)
Dilated Cardiomyopathy
Device: AccuCinch Ventricular Restoration System
Drug: Guideline-Directed Medical Therapy

The purpose of this clinical study is to assess the safety and effectiveness of the Atrial Flow Regulator in the treatment of subjects, 18 years of a...

Active, not recruiting
Heart Failure With Preserved Ejection Fraction (HFpEF)
Heart Failure With Reduced Ejection Fraction (HFrEF)
Device: Atrial Flow Regulator
Device: Sham Comparator

The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve DMS system to Optimal Diuretic Therapy (ODT...

Active, not recruiting
Acute Decompensated Heart Failure
Device: Reprieve Decongestion Management System
Drug: Diuretic

The trial will evaluate efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneou...

Enrolling
Systemic Lupus Erythematosus
Drug: Placebo
Drug: Ianalumab

The purpose of this research study is to evaluate whether using the the IMPELLA® CP System temporary circulatory assist device for 30 minutes prior t...

Active, not recruiting
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Device: Impella CP® placement prior to reperfusion with Primary PCI

Trial sponsors

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