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Active trials

6 of 17 total trials

Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Rest...

Enrolling
Heart Failure with Reduced Ejection Fraction (HFrEF)
Dilated Cardiomyopathy
Device: AccuCinch Ventricular Restoration System
Drug: Guideline-Directed Medical Therapy

The purpose of this clinical study is to assess the safety and effectiveness of the Atrial Flow Regulator in the treatment of subjects, 18 years of a...

Active, not recruiting
Heart Failure With Preserved Ejection Fraction (HFpEF)
Heart Failure With Reduced Ejection Fraction (HFrEF)
Device: Atrial Flow Regulator
Device: Sham Comparator

The trial will evaluate efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneou...

Enrolling
Systemic Lupus Erythematosus
Drug: Placebo
Drug: Ianalumab

The purpose of this research study is to evaluate whether using the the IMPELLA® CP System temporary circulatory assist device for 30 minutes prior t...

Active, not recruiting
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Device: Impella CP® placement prior to reperfusion with Primary PCI
Locations recently updated

Multi-center, randomized, controlled, open-label Phase 2 feasibility trial. Subjects on mechanical ventilation (MV) for acute hypoxemic respiratory f...

Enrolling
ARDS (Moderate or Severe)
AHRF
Device: Phrenic Nerve Stimulation

A randomized, double-blind, placebo controlled, 2-arm multicenter phase 3 study to assess the efficacy and safety of ianalumab in patients with activ...

Active, not recruiting
Sjogren Syndrome
Biological: VAY736
Other: Placebo

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