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Rutgers Robert Wood Johnson Medical School | Internal Medicine/Gastroenterology Division - Advanced Endoscopy Research

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Active trials

14 of 53 total trials

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

The purpose of this clinical trial is to learn about the safety, extent of the side effects, and immune responses of the study vaccine (called varian...

Enrolling
COVID-19
SARS-CoV-2 Virus
Biological: Bivalent BNT162b2 (original/Omicron BA.4/BA.5) 10 microgram dose
Biological: Variant-adapted BNT162b2 (Omicron XBB.1.5) 3 microgram dose

Researchers are looking for a better way to treat hemophilia A. Hemophilia A is a genetic disorder where the body does not create enough of a protein...

Active, not recruiting
Prophylaxis of Bleeding
Treatment of Bleeding
Biological: Damoctocog alfa pegol (Jivi, BAY94-9027)

The objective of this study is to establish the safety and effectiveness of the Edwards SAPIEN X4 Transcatheter Heart Valve (THV) in subjects with sy...

Active, not recruiting
Aortic Stenosis, Severe
Device: SAPIEN X4 THV

The goal of this real-world, multi-center, randomized, outpatient study is to assess the effectiveness of the Biofourmis cloud based BiovitalsHF plat...

Active, not recruiting
Heart Failure
Device: BiovitalsHF

The objective of the study is to evaluate the safety and effectiveness of the HARPOON™ System in the treatment of patients with severe degenerative m...

Active, not recruiting
Mitral Regurgitation
Device: HARPOON™ Beating Heart Mitral Valve Repair System

Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Rest...

Enrolling
Heart Failure with Reduced Ejection Fraction (HFrEF)
Dilated Cardiomyopathy
Device: AccuCinch Ventricular Restoration System
Drug: Guideline-Directed Medical Therapy

To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Repair System in patients with symptomatic severe tricuspid regurgitati...

Enrolling
Tricuspid Valve Insufficiency
Tricuspid Valve Disease
Device: Edwards PASCAL System
Drug: Optimal Medical Therapy

The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical mea...

Active, not recruiting
Parkinson's Disease
Drug: Placebo
Drug: BIA 28-6156 60 mg

To assess the pharmacokinetics, pharmacodynamics and safety of Epeleuton capsules in adult SCD patients who are aged ≥18 years.

Enrolling
Sickle Cell Disease
Drug: Epeleuton

The purpose of this research study is to evaluate whether using the the IMPELLA® CP System temporary circulatory assist device for 30 minutes prior t...

Active, not recruiting
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Device: Impella CP® placement prior to reperfusion with Primary PCI

This study objective is to establish the safety and effectiveness of the Edwards SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA Transcatheter Hea...

Enrolling
Aortic Valve Stenosis
Aortic Stenosis, Calcific
Device: SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA

Randomized, open-label, multi-center, comparative trial to assess the efficacy and safety in immunocompromised subjects with acyclovir resistant or a...

Enrolling
HSV Infection
Drug: Investigator's choice
Drug: Pritelivir

Pivotal trial to evaluate the safety and effectiveness of the Edwards EVOQUE tricuspid valve replacement system

Active, not recruiting
Heart Valve Diseases
Tricuspid Valve Insufficiency
Device: Edwards EVOQUE System
Drug: Optimal Medical Therapy

The overall objective of the RESTORATiVE303 study is to evaluate the safety and the Clostridioides difficile infection (CDI) recurrence rate at Week...

Enrolling
CDI
C.Difficile Diarrhea
Biological: Placebo
Biological: VE303

Trial sponsors

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