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Rutgers Robert Wood Johnson Medical School | Internal Medicine/Gastroenterology Division - Advanced Endoscopy Research

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Active trials

15 of 49 total trials

A Study to Learn About the Amount of the Study Medicine (Sisunatovir) in Blood and Its Safety in Infants and Children With Pneumonia Caused by RSV

The purpose of the study is to learn about the safety and amount of sisunatovir in the blood of infants and children up to age 60 months. These child...

Enrolling
Respiratory Syncytial Virus Infections
Drug: Placebo
Drug: Active

The purpose of this clinical trial is to learn about the safety, extent of the side effects, and immune responses of the study vaccine (called varian...

Enrolling
COVID-19
SARS-CoV-2 Virus
Biological: Variant-adapted BNT162b2 (Omicron XBB.1.5) 3 microgram dose
Biological: Variant-adapted BNT162b2 (Omicron XBB.1.5) 10 microgram dose

Researchers are looking for a better way to treat hemophilia A. Hemophilia A is a genetic disorder where the body does not create enough of a protein...

Active, not recruiting
Prophylaxis of Bleeding
Treatment of Bleeding
Biological: Damoctocog alfa pegol (Jivi, BAY94-9027)

The objective of this study is to establish the safety and effectiveness of the Edwards SAPIEN X4 Transcatheter Heart Valve (THV) in subjects with sy...

Enrolling
Aortic Stenosis, Severe
Device: SAPIEN X4 THV

The goal of this real-world, multi-center, randomized, outpatient study is to assess the effectiveness of the Biofourmis cloud based BiovitalsHF plat...

Active, not recruiting
Heart Failure
Device: BiovitalsHF

The objective of the study is to evaluate the safety and effectiveness of the HARPOON™ System in the treatment of patients with severe degenerative m...

Active, not recruiting
Mitral Regurgitation
Device: HARPOON™ Beating Heart Mitral Valve Repair System

To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Repair System in patients with symptomatic severe tricuspid regurgitati...

Enrolling
Tricuspid Valve Insufficiency
Tricuspid Valve Disease
Drug: Optimal Medical Therapy
Device: Edwards PASCAL System

The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical mea...

Enrolling
Parkinson's Disease
Drug: Placebo
Drug: BIA 28-6156 60 mg

To assess the pharmacokinetics, pharmacodynamics and safety of Epeleuton capsules in adult SCD patients who are aged ≥18 years.

Enrolling
Sickle Cell Disease
Drug: Epeleuton

The purpose of this research study is to evaluate whether using the the IMPELLA® CP System temporary circulatory assist device for 30 minutes prior t...

Enrolling
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Device: Impella CP® placement prior to reperfusion with Primary PCI

This study objective is to establish the safety and effectiveness of the Edwards SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA Transcatheter Hea...

Enrolling
Aortic Valve Stenosis
Aortic Stenosis, Calcific
Device: SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA

Researchers are looking for a better way to treat people who have hemophilia A. Hemophilia A is a genetic bleeding disorder that is caused by the lac...

Enrolling
Prophylaxis of Bleeding
Hemophilia A
Biological: Damoctocog alfa-pegol is a recombinant B-domain deleted human coagulation FVIII variant site specifically conjugated with a 60 kDa, branched (30 kDa each) polyethylene glycol (PEG).

A phase 2, multi-center, double-blind, randomized, placebo-controlled study to evaluate the safety, phage kinetics, and efficacy of inhaled AP-PA02 a...

Enrolling
Lung Infection
Non-cystic Fibrosis Bronchiectasis
Other: Placebo
Biological: AP-PA02
Locations recently updated

Randomized, open-label, multi-center, comparative trial to assess the efficacy and safety in immunocompromised subjects with acyclovir resistant or a...

Enrolling
HSV Infection
Drug: Investigator's choice
Drug: Pritelivir

Pivotal trial to evaluate the safety and effectiveness of the Edwards EVOQUE tricuspid valve replacement system

Enrolling
Heart Valve Diseases
Tricuspid Valve Insufficiency
Drug: Optimal Medical Therapy
Device: Edwards EVOQUE System

Trial sponsors

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