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Seattle Cancer Care Alliance | Division of Medical Oncology - Hematologic Malignancies - UW Medicine

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Cyclophosphamide
Fludarabine
Dexamethasone
PDR001
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Active trials

10 of 91 total trials

A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

A Phase 1 Open-label, Multi-center Study of the Safety, Pharmacokinetics (PK), and Anti-tumor Activity of LYT- 200 in Patients with Relapsed/Refracto...

Enrolling
MDS
AML, Adult Recurrent
Drug: Azacitidine
Drug: Decitabine

The purpose of the study is to compare the efficacy of talquetamab subcutaneous(ly) (SC) in combination with daratumumab SC and pomalidomide (Tal-DP)...

Active, not recruiting
Relapsed or Refractory Multiple Myeloma
Drug: Talquetamab
Drug: Dexamethasone

This Phase III, randomized, double-blind, placebo-controlled study will compare the efficacy, safety, and pharmacokinetics of polatuzumab vedotin plu...

Active, not recruiting
Diffuse Large B-Cell Lymphoma
Drug: Vincristine Placebo
Drug: Polatuzumab vedotin Placebo

This is an open-label, multi-center Phase 1/2 study of oral LOXO-305 (pirtobrutinib) in patients with CLL/SLL and NHL who have failed or are intolera...

Active, not recruiting
Waldenstrom Macroglobulinemia
Marginal Zone Lymphoma
Drug: Venetoclax
Drug: Rituximab

The purpose of this study is to assess the safety profile of relatlimab plus nivolumab in combination with platinum doublet chemotherapy (PDCT) and t...

Active, not recruiting
Metastatic Non-small Cell Lung Cancer
Non-small Cell Lung Cancer
Drug: Nab-Paclitaxel
Drug: Cisplatin

This is a randomized study to compare the efficacy and safety of zanubrutinib plus rituximab versus bendamustine plus rituximab in previously untreat...

Active, not recruiting
Mantle Cell Lymphoma; Non-Hodgkin Lymphoma
Drug: rituximab
Drug: zanubrutinib

This randomized phase III trial studies how well avelumab works in treating patients with Merkel cell cancer that has spread to the lymph nodes and h...

Active, not recruiting
Stage IIIB Merkel Cell Carcinoma AJCC v8
Stage III Merkel Cell Carcinoma AJCC v8
Other: Placebo
Other: Peripheral Blood Collection

This is a study of the efficacy, pharmacokinetics, and safety of DS-1062a in participants with advanced or metastatic non-small cell lung cancer (NSC...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: DS-1062a

This study is a phase 2 / 3 prospective, double-blind, randomized, multicenter, placebo-controlled study for prevention of acute GVHD (aGVHD) in part...

Enrolling
Acute-graft-versus-host Disease
Biological: AAT
Biological: Placebo

A 10 week trial to assess the ability of Tempol to prevent and/or reduce toxicities associated with cisplatin and radiation treatment in head and nec...

Enrolling
Nephrotoxicity
Ototoxicity
Drug: Placebo Solution
Drug: Tempol

Trial sponsors

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University of Washington logo
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Janssen (J&J Innovative Medicine) logo

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