Universitätsklinikum Ulm | Innere Medizin III
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The primary objective of this study is to determine the safety and tolerability of multiple doses of QRL-201 in people living with ALS
Full description
This first-in-human, Phase 1 study will evaluate the safety, tolerability, and pharmacokinetics (PK) of QRL-201 administered intrathecal (IT) to participants with Amyotrophic Lateral Sclerosis. Two dose escalation cohorts of 8 participants each, followed by an additional 48 participants, receiving the study drug in a 6:2 ratio of QRL-201 to placebo.
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Interventional model
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64 participants in 4 patient groups, including a placebo group
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Central trial contact
QurAlis Corporation
Data sourced from clinicaltrials.gov
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