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Universitätsklinikum Ulm | Innere Medizin III

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Atezolizumab
Lenalidomide
Gemcitabine
Bevacizumab
Carboplatin
Obinutuzumab
Paclitaxel
LY2835219
Azacitidine
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Active trials

95 of 330 total trials

A Phase 3 Study of Obexelimab in Patients with IgG4-Related Disease (INDIGO)

This study aims to examine the efficacy and safety of obexelimab for the prevention of flare of IgG4-related disease (IgG4-RD)

Active, not recruiting
IgG4 Related Disease
Drug: Obexelimab
Other: Placebo

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal demen...

Active, not recruiting
Frontotemporal Dementia
Drug: Open label - AL001
Drug: AL001

This is a multi-site, open-label, Phase II, randomized, trial to compare the efficacy of RO7198457 versus watchful waiting in patients with circulati...

Enrolling
Colorectal Cancer Stage III
Colorectal Cancer Stage II
Drug: RO7198457 intravenous (IV)
Other: Observational group (no intervention)

The Alternative-C Trial is a prospective, multicenter Phase 2 Study to evaluate the efficacy of the chemotherapy-free combination of copanlisib and o...

Active, not recruiting
Follicular Lymphoma
Drug: Obinutuzumab
Drug: Copanlisib

This is a Phase IIIb, single-arm, multicenter, OLE study. Participants receiving ocrelizumab as an investigational medicinal product (IMP) in a Roche...

Active, not recruiting
Multiple Sclerosis
Drug: Ocrelizumab

The purpose of this study is to assess the efficacy and safety of tiragolumab, an anti-TIGIT monoclonal antibody, when administered in combination wi...

Active, not recruiting
Carcinoma, Hepatocellular
Drug: Tiragolumab
Other: Placebo

This open-label, exploratory study is designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or combina...

Enrolling
Metastatic Colorectal Cancer
Drug: Inavolisib
Drug: Bevacizumab

The primary objective of this study is to determine the safety and tolerability of multiple doses of QRL-201 in people living with ALS

Enrolling
Amyotrophic Lateral Sclerosis
Drug: Multiple ascending doses of QRL-201
Drug: QRL-201

This study will assess the safety, tolerability, pharmaokinetics, and preliminary efficacy of mosunetuzumab (Lunsumio) monotherapy in participants wi...

Enrolling
Chronic Lymphocytic Leukemia
Drug: Tocilizumab
Drug: Venetoclax

This is an open-label, multicenter, extension study. Patients who are receiving clinical benefit from atezolizumab monotherapy or atezolizumab in com...

Active, not recruiting
Cancer
Drug: Emactuzumab
Drug: Niraparib

This study has 2 parts. The first part of the study is done. The first part was open to adults with different types of advanced cancer (solid tumors)...

Active, not recruiting
Neoplasms
Drug: BI 907828
Drug: ezabenlimab

The main purpose of this study is to evaluate the safety and efficacy of abemaciclib plus tamoxifen or abemaciclib alone in women with previously tre...

Active, not recruiting
Metastatic Breast Cancer
Drug: Abemaciclib
Drug: Prophylactic Loperamide

This study will evaluate the efficacy and safety of adjuvant therapy with atezolizumab plus bevacizumab compared with active surveillance in particip...

Active, not recruiting
Carcinoma, Hepatocellular
Drug: Bevacizumab
Drug: Atezolizumab

This is a global Phase III, randomized, placebo-controlled, double-blind study designed to evaluate the efficacy and safety of adjuvant treatment wit...

Active, not recruiting
Muscle-invasive Bladder Cancer
Device: Signatera
Other: Placebo

This is a Phase III, open-label, multicenter, randomized, two-arm study designed to evaluate the efficacy and safety of atezolizumab plus either lenv...

Active, not recruiting
Unresectable Hepatocellular Carcinoma
Drug: Lenvatinib
Drug: Atezolizumab

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed therapies (...

Enrolling
Leukemia, Myeloid, Acute
Drug: Cytarabine
Drug: Bleximenib

The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severe...

Enrolling
Ulcerative Colitis Chronic
Ulcerative Colitis
Drug: Placebo
Drug: Eltrekibart

This study will evaluate the safety of tobemstomig (RO7247669) in combination with axitinib alone or with tiragolumab (anti-TIGIT) and axitinib as co...

Active, not recruiting
Renal Cell Carcinoma
Drug: Tobemstomig
Drug: Tiragolumab

The purpose of this study is to determine the recommended Phase 2 dose regimen or the maximum tolerated dose of JNJ-67856633 in participants with rel...

Active, not recruiting
Lymphoma, Non-Hodgkin
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: JNJ-67856633

The primary purpose of this study is to compare the efficacy of the study drug LY2875358, given together with erlotinib, against erlotinib, alone. Pa...

Active, not recruiting
Carcinoma, Non-Small-Cell Lung
Biological: LY2875358
Drug: Erlotinib

Trial sponsors

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