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Universitätsklinikum Ulm | Innere Medizin III

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Lenalidomide
Carboplatin
Paclitaxel
Obinutuzumab
Cytarabine
Idarubicin
Empagliflozin
Abemaciclib
Azacitidine
Gemcitabine

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Active trials

79 of 282 total trials

2nd-line Therapy With Nal-IRI After Gem/Nab-pac in Advanced Pancreatic Cancer - Predictive Role of 1st-line Therapy (PREDICT)

Second-line therapy with Nal-IRI after failure gemcitabine/nab-paclitaxel in advanced pancreatic cancer - predictive role of 1st-line therapy

Active, not recruiting
Locally Advanced Pancreatic Cancer
Metastatic Pancreatic Cancer
Drug: Irinotecan Liposomal Injection [Onivyde]

This study will evaluate the safety, tolerability, and preliminary antitumor activity of CAN04 both as a monotherapy and in combination with standard...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
Non Small Cell Lung Cancer
Drug: Pemetrexed
Drug: Gemcitabine

A phase 2 randomized, double blind, placebo controlled study evaluating the efficacy and safety of AL002 in participants with Early Alzheimer's Disea...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: AL002

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal demen...

Active, not recruiting
Frontotemporal Dementia
Drug: Open label - AL001
Drug: AL001

A Phase Ib/II multicentre open label study of bemcentinib (BGB324) as a single agent in participants with Acute Myeloid Leukemia (AML) or Myelodyspla...

Active, not recruiting
Myelodysplastic Syndromes
Acute Myeloid Leukemia
Drug: Cytarabine
Drug: Decitabine

This is a multi-site, open-label, Phase II, randomized, trial to compare the efficacy of RO7198457 versus watchful waiting in patients with circulati...

Enrolling
Colorectal Cancer Stage III
Colorectal Cancer Stage II
Drug: RO7198457 intravenous (IV)
Other: Observational group (no intervention)

The Alternative-C Trial is a prospective, multicenter Phase 2 Study to evaluate the efficacy of the chemotherapy-free combination of copanlisib and o...

Active, not recruiting
Follicular Lymphoma
Drug: Obinutuzumab
Drug: Copanlisib

he purpose of the study is to evaluate the efficacy, safety, and tolerability BGB-3111 plus obinutuzumab versus obinutuzumab alone in participants wi...

Active, not recruiting
Relapsed/Refractory Follicular Non-Hodgkin Lymphoma
Drug: Obinutuzumab
Drug: Zanubrutinib

The primary objective of this study is to determine the safety and tolerability of multiple doses of QRL-201 in people living with ALS

Enrolling
Amyotrophic Lateral Sclerosis
Drug: QRL-201 - Dose 3
Drug: QRL-201 - Dose 7

This study has 2 parts. The first part of the study is done. The first part was open to adults with different types of advanced cancer (solid tumors)...

Active, not recruiting
Neoplasms
Drug: BI 907828
Drug: ezabenlimab

The main purpose of this study is to measure how well abemaciclib works in participants with early breast cancer who are taking hormone therapy after...

Active, not recruiting
Breast Neoplasms
Drug: Placebo
Drug: Abemaciclib

The main purpose of this study is to evaluate the safety and efficacy of abemaciclib plus tamoxifen or abemaciclib alone in women with previously tre...

Active, not recruiting
Metastatic Breast Cancer
Drug: Abemaciclib
Drug: Prophylactic Loperamide

The purpose of this study is to determine the recommended Phase 2 dose regimen or the maximum tolerated dose of JNJ-67856633 in participants with rel...

Active, not recruiting
Lymphoma, Non-Hodgkin
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: JNJ-67856633

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of JNJ-75276617 in combination with AML directed therapies...

Enrolling
Leukemia, Myeloid, Acute
Drug: Azacitidine (AZA)
Drug: Cytarabine

The primary purpose of this study is to compare the efficacy of the study drug LY2875358, given together with erlotinib, against erlotinib, alone. Pa...

Active, not recruiting
Carcinoma, Non-Small-Cell Lung
Biological: LY2875358
Drug: Erlotinib

The purpose of this study is to evaluate the safety, tolerability, and efficacy of mavacamten compared with placebo in participants with symptomatic...

Active, not recruiting
Cardiomyopathy, Hypertrophic
Drug: Mavacamten
Other: Placebo

The purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravi...

Enrolling
Myasthenia Gravis
Drug: Nipocalimab
Drug: Placebo

The main purpose of this study is to evaluate how effective nonsteroidal aromatase inhibitors (NSAI) plus abemaciclib are in postmenopausal women wit...

Active, not recruiting
Breast Cancer
Drug: Letrozole
Drug: Placebo

The purpose of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL. Participants...

Enrolling
Leukemia, B-cell
Small Lymphocytic Lymphoma
Drug: Pirtobrutinib
Drug: Ibrutinib

The main purpose of this study is to evaluate the efficacy and safety of ramucirumab or merestinib or placebo plus cisplatin and gemcitabine in parti...

Active, not recruiting
Advanced Cancer
Metastatic Cancer
Drug: Ramucirumab
Drug: Gemcitabine

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