Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash Infestation

Eye Research Foundation, Inc.

Status and phase: Completed; Phase 4

Conditions: Blepharitis

Treatments: Drug: Moxidectin 2 MG Oral Tablet; Drug: Placebo

Study type: Interventional

Funder types: Industry

Identifiers

NCT06795165

MOX-001

Details and patient eligibility

About

A Single-Center, Investigator-Masked, Randomized, Placebo-Controlled, Investigator Initiated Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash Infestation

Enrollment: 24 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Active blepharitis with collarettes

Exclusion criteria

• Other clinically significant eye disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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24 participants in 3 patient groups, including a placebo group

Active

Active Comparator group

Treatment:

Drug: Moxidectin 2 MG Oral Tablet

Active and Placebo

Experimental group

Treatment:

Drug: Placebo

Drug: Moxidectin 2 MG Oral Tablet

Placebo

Placebo Comparator group

Treatment:

Drug: Placebo