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Find clinical trials for Adenocarcinoma in Toronto, ON

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Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Colorectal Cancer
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Esophageal Cancer
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Adenocarcinoma trials near Toronto, ON, CAN:

Locations recently updated

A Study to Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (AndroMETa-GEA)

participants to treat locally advanced unresectable or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma (mGEA).T...

Enrolling
Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Budigalimab
Drug: Oxaliplatin

Phase 2

AbbVie
AbbVie

Toronto, Ontario, Canada and 44 other locations

resectable gastric, gastroesophageal junction (GEJ), or esophageal adenocarcinoma who have not received previous treatment for the disease....

Enrolling
Gastroesophageal Adenocarcinoma
Drug: 5-Fluorouracil (5-FU)
Drug: Capecitabine

Phase 2

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 67 other locations

Recently updated

This study is being done to answer the following question:Can the chance of gastroesophageal cancer growing or spreading be lowered by adding a drug...

Enrolling
Gastroesophageal Adenocarcinoma
Drug: Zanidatamab
Drug: Paclitaxel

Phase 2

Canadian Cancer Trials Group

Toronto, Ontario, Canada and 17 other locations

The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Toronto, Canada and 124 other locations

This study is being done to answer the main question of: Do patients with colorectal cancer that cannot be removed by surgery, that is treated with t...

Begins enrollment this month
Colorectal Cancer
Drug: Balstilimab
Other: Best Supportive Care

Phase 3

Canadian Cancer Trials Group

Toronto, Ontario, Canada and 5 other locations

with chemotherapy in participants with previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma...

Begins enrollment in 1 month
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Drug: Nivolumab
Drug: Pumitamig

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Toronto, Ontario, Canada and 157 other locations

first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Active, not recruiting
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Drug: Domvanalimab
Drug: Zimberelimab

Phase 3

Arcus Biosciences
Arcus Biosciences

Toronto, Canada and 212 other locations

after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: Pemetrexed
Drug: Rilvegostomig

Phase 3

AstraZeneca
AstraZeneca

Oshawa, Ontario, Canada and 98 other locations

This study is being done to find out if zanidatamab, when given with chemotherapy plus or minus tislelizumab, is safe and works better than trastuzum...

Active, not recruiting
Gastroesophageal Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Tislelizumab
Drug: Capecitabine

Phase 3

Jazz Pharmaceuticals
Jazz Pharmaceuticals

Toronto, Canada and 229 other locations

and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: Docetaxel
Drug: Irinotecan

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 185 other locations

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