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Find clinical trials for Adenocarcinoma in Toronto, ON

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Carcinoma
Cancer
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Colorectal Cancer
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Esophageal Cancer

Adenocarcinoma trials near Toronto, ON, CAN:

Locations recently updated

Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma

This study is being done to answer the following question:Can the chance of gastroesophageal cancer growing or spreading be lowered by adding a drug...

Enrolling
Gastroesophageal Adenocarcinoma
Drug: Zanidatamab
Drug: Paclitaxel

Phase 2

Canadian Cancer Trials Group

Toronto, Ontario, Canada and 7 other locations

and placebo in first-line metastatic pancreatic ductal adenocarcinoma (mPDAC).This study aims to explore whether blockade of Transforming Gr...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Nab-paclitaxel
Drug: Gemcitabine

Phase 3

Novartis
Novartis

Toronto, Ontario, Canada and 113 other locations

mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior systemic anti-cancer tre...

Enrolling
Adenocarcinoma, Pancreatic Ductal
Drug: mFOLFIRINOX
Drug: Autogene cevumeran

Phase 2

Genentech
Genentech

Toronto, Ontario, Canada and 36 other locations

The standard or usual treatment for this disease consists of two chemotherapy drugs gemcitabine and nab-paclitaxel given together.

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Gemcitabine
Drug: Tremelimumab

Phase 2

Canadian Cancer Trials Group

Toronto, Ontario, Canada and 26 other locations

adenocarcinoma (GEA), biliary tract cancer (BTC), or colorectal cancer (CRC)....

Active, not recruiting
HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
Drug: Oxaliplatin
Drug: Fluorouracil

Phase 2

Jazz Pharmaceuticals
Jazz Pharmaceuticals

Toronto, Ontario, Canada and 20 other locations

first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Active, not recruiting
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Drug: Domvanalimab
Drug: Zimberelimab

Phase 3

Arcus Biosciences
Arcus Biosciences

Toronto, Canada and 212 other locations

and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: AZD0901
Drug: Docetaxel

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 157 other locations

The purpose of this study is to assess the efficacy and safety of lenvatinib (E7080/MK-7902) plus pembrolizumab (MK-3475) plus chemotherapy compared...

Active, not recruiting
Advanced/Metastatic Gastroesophageal Adenocarcinoma
Drug: 5-FU
Biological: Lenvatinib

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Hamilton, Ontario, Canada and 176 other locations

unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical st...

Active, not recruiting
Metastatic Gastric Adenocarcinoma or Cancer
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
Drug: fluorouracil
Drug: zolbetuximab

Phase 3

Astellas
Astellas

Toronto, Ontario, Canada and 219 other locations

This study is being done to find out if zanidatamab, when given with chemotherapy plus or minus tislelizumab, is safe and works better than trastuzum...

Enrolling
Gastroesophageal Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Tislelizumab
Drug: Capecitabine

Phase 3

Jazz Pharmaceuticals
Jazz Pharmaceuticals

Toronto, Canada and 316 other locations

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