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Find clinical trials for Adenocarcinoma in Toronto, ON

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Related conditions:

Pancreatic Cancer
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Stomach Cancer
Prostatic Cancer
Neoplasm Metastasis
Esophageal Cancer

Adenocarcinoma trials near Toronto, ON, CAN:

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma (RASolute 303)

The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combinatio...

Enrolling
Pancreatic Adenocarcinoma Metastatic
PDAC - Pancreatic Ductal Adenocarcinoma
Drug: daraxonrasib
Drug: nab-paclitaxel

Phase 3

Revolution Medicines
Revolution Medicines

Toronto, Ontario, Canada and 48 other locations

(CLDN18.2)-positive, human epidermal growth factor receptor 2 (HER2)-negative, gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Enrolling
Gastroesophageal Junction Adenocarcinoma
Esophageal Cancer
Drug: Sonesitatug vedotin
Drug: Nivolumab

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 308 other locations

participants to treat locally advanced unresectable or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma (mGEA).T...

Active, not recruiting
Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Budigalimab
Drug: Oxaliplatin

Phase 2

AbbVie
AbbVie

Toronto, Ontario, Canada and 48 other locations

This study will test a new personalized treatment approach for patients with stomach or esophageal cancer. It will take place in two stages and aims...

Enrolling
Gastroesophageal Adenocarcinoma
Drug: Oxaliplatin
Drug: Zolbetuximab

Phase 2

American Association for Cancer Research

Toronto, Ontario, Canada and 2 other locations

resectable gastric, gastroesophageal junction (GEJ), or esophageal adenocarcinoma who have not received previous treatment for the disease....

Enrolling
Gastroesophageal Adenocarcinoma
Drug: Sonesitatug Vedotin
Drug: Calcium folinate

Phase 2

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 69 other locations

The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Toronto, Canada and 118 other locations

This study is being done to answer the following question:Can the chance of gastroesophageal cancer growing or spreading be lowered by adding a drug...

Enrolling
Gastroesophageal Adenocarcinoma
Drug: Zanidatamab
Drug: Paclitaxel

Phase 2

Canadian Cancer Trials Group

Toronto, Ontario, Canada and 17 other locations

with chemotherapy in participants with previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma...

Enrolling
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Drug: Nivolumab
Drug: Pumitamig

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Toronto, Ontario, Canada and 160 other locations

after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: Pemetrexed
Drug: Rilvegostomig

Phase 3

AstraZeneca
AstraZeneca

Oshawa, Ontario, Canada and 89 other locations

This study is being done to find out if zanidatamab, when given with chemotherapy plus or minus tislelizumab, is safe and works better than trastuzum...

Active, not recruiting
Gastroesophageal Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Tislelizumab
Drug: Capecitabine

Phase 3

Jazz Pharmaceuticals
Jazz Pharmaceuticals

Toronto, Canada and 230 other locations

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