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Find clinical trials for Alzheimer's Disease in Charlotte, NC

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Psychotic Disorders
Brain Diseases
Neurodegenerative Diseases

Alzheimer's Disease trials near Charlotte, NC, USA:

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)

This is a randomized, double-blind, sham-controlled, adaptive-design pivotal study of sensory stimulation in subjects with mild to moderate Alzheimer's...

Enrolling
Alzheimer Disease 6
Dementia of Alzheimer Type
Device: Sensory Stimulation System (GS120) - Sham
Device: Sensory Stimulation System (GS120) - Active
Cognito Therapeutics
Cognito Therapeutics

Matthews, North Carolina, United States and 67 other locations

reason for this study is to collect safety and efficacy information regarding the study drug remternetug in participants with early symptomatic Alzheimer's...

Active, not recruiting
Alzheimer's Disease
Drug: Remternetug (SC)
Drug: Placebo

Phase 3

Lilly
Lilly

Matthews, North Carolina, United States and 75 other locations

on the change from baseline at 18 months in cerebrospinal fluid (CSF) microtubule-binding region (MTBR)-tau-243 in participants with early Alzheimer's...

Enrolling
Alzheimer's Disease
Drug: E2814
Drug: Lecanemab

Phase 2

Eisai
Eisai

Matthews, North Carolina, United States and 34 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Active, not recruiting
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Matthews, North Carolina, United States and 109 other locations

-323511 among adults with Agitation Associated with Dementia due to Alzheimer's Disease.Part A consists of a Screening Period (up t...

Enrolling
Alzheimer's Disease
Healthy Elderly
Drug: Placebo
Drug: NMRA-323511

Phase 1

Neumora Therapeutics

Charlotte, North Carolina, United States and 23 other locations

administered once every four weeks (Q4W) in slowing cognitive and functional decline as compared to placebo in participants with early Alzheimer's...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: sabirnetug

Phase 2

Acumen Pharmaceuticals

Matthews, North Carolina, United States and 96 other locations

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...

Active, not recruiting
Early Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Charlotte, North Carolina, United States and 246 other locations

The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (inclu...

Active, not recruiting
Alzheimer's Disease
Drug: GSK4527226
Other: Placebo

Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Matthews, North Carolina, United States and 98 other locations

Locations recently updated

The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: KarXT

Phase 3

Karuna Therapeutics
Karuna Therapeutics

Matthews, North Carolina, United States and 218 other locations

Randomized efficacy and safety study of piromelatine 20 mg versus placebo in participants with mild dementia due to Alzheimer's disease...

Active, not recruiting
Alzheimer's Disease
Drug: Piromelatine 20 mg
Drug: Placebo

Phase 2, Phase 3

Neurim Pharmaceuticals

Matthews, North Carolina, United States and 36 other locations

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